CAS 76144-81-5

Meldonium

Descrizione:

Meldonium, noto anche come Mildronato, è un composto sintetico utilizzato principalmente come farmaco per trattare condizioni cardiache ischemiche e migliorare le prestazioni fisiche. È stato sviluppato negli anni '70 in Lettonia ed è classificato come un modulatore metabolico. La formula chimica di Meldonium è C5H13N1O2 e presenta una struttura unica che include un anello di 1,2,4-triazolo. Meldonium agisce inibendo l'enzima carnitina aciltransferasi, che gioca un ruolo nel metabolismo degli acidi grassi, promuovendo così l'utilizzo del glucosio rispetto agli acidi grassi per la produzione di energia. Questo cambiamento può migliorare la resistenza e ridurre la fatica durante lo sforzo fisico. La sostanza ha attirato l'attenzione nello sport a causa dei suoi effetti migliorativi delle prestazioni, portando alla sua inclusione nell'elenco delle sostanze proibite dell'Agenzia Mondiale Antidoping. Sebbene sia generalmente ben tollerata, gli effetti collaterali potenziali possono includere mal di testa, vertigini e disturbi gastrointestinali. Il suo uso deve essere monitorato, specialmente in individui con condizioni di salute preesistenti.

Formula: C₆H₁₄N₂O₂

InChI: InChI=1/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5?,6-,7-,8?/m1/s1

InChI key: InChIKey=PVBQYTCFVWZSJK-UHFFFAOYSA-N

SMILES: N(CCC([O-])=O)[N+](C)(C)C

Sinonimi:

• 1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion
• 2-(2-Carboxyethyl)-1,1,1-Trimethylhydrazinium Hydroxide Inner Salt
• 2-(2-Carboxyethyl)-1,1,1-trimethyl Hydrazinium Inner Salt
• 3-(2,2,2-Trimethylhydrazine)Propionate
• 3-(2,2,2-Trimethylhydrazinium)propionate
• 3-(Trimethylammonioamino)Propanoate
• 3-[(Trimethylazaniumyl)amino]propanoate
• Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, inner salt
• Hydrinol
• Idrinol
• Meldomiun
• Meldonium
• Met 88
• Met88
• Mildonate
• Quateri
• Quaterin
• Vasonat
• Mildronate
• N-Trimethyl-hydrazine-3-propionate
• 1,1,1-Trimethylhydrazinium 2-propionate
• 3-[(Trimethylaminio)amino]propionic acidanion
• 2-(2-Carboxylatoethyl)-1,1,1-trimethylhydrazinium

1,1,1-Trimethyl-2-(2-carboxyethyl)hydrazine zwitterion

CAS: 76144-81-5

Formula: C₆H₁₄N₂O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 146.1876

Ref: IN-DA00IKH3

Mildronate-d3

CAS: 76144-81-5

Formula: C₆H₁₁N₂O₂D₃

Colore e forma: White To Off-White Solid

Peso molecolare: 149.21

Ref: 4Z-M-511

Mildronate-d3 HCl

CAS: 76144-81-5

Formula: C₆H₁₁D₃N₂O₂·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 149.21 36.46

Ref: 4Z-M-515

Mildronate

CAS: 76144-81-5

Formula: C₆H₁₄N₂O₂

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 146.19

Ref: 7W-GP7996

Mildronate

CAS: 76144-81-5

Formula: C₆H₁₄N₂O₂

Peso molecolare: 146.19

Ref: 4Z-M-512

Mildronate

CAS: 76144-81-5

Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine

Formula: C₆H₁₄N₂O₂

Purezza: 99.94%

Colore e forma: White Crystalline Powder

Peso molecolare: 146.19

Ref: TM-T3268

Mildronate-d3

Prodotto controllato

CAS: 76144-81-5

Stability Very Hygroscopic
Applications Mildronate-d3 is the labeled analogue of Mildronate (M344450), a novel pharmaceutical composition based on a reverse transcriptase inhibitor and meldonium. May contain a significant amount of water.

Formula: C₆H₁₁D₃N₂O₂

Colore e forma: White To Off-White

Peso molecolare: 149.21

Ref: TR-M344452

Meldonium

Prodotto controllato

CAS: 76144-81-5

Mildronate is a drug with a matrix effect that has been shown to be effective in experimental models. Mildronate is used to treat cardiac arrhythmias and myocardial infarcts, as well as other cardiovascular diseases. Mildronate also has pharmacological effects on the brain, including protecting against brain toxicity and improving cognitive functions. The drug has been shown to have an effect on the blood pressure, energy metabolism, and pharmacological treatment of diseases. Mildronate was discovered during an analytical study of erythrocyte membranes and its effects were studied in detail. It was found that mildronate improved the membrane's stability and increased its resistance to hemolysis. This discovery led scientists to investigate mildronate as a possible treatment for heart conditions involving blood clots or low blood flow.

Formula: C₆H₁₄N₂O₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 146.19 g/mol

Ref: 3D-FM26003

Meldonium

Prodotto controllato

CAS: 76144-81-5

Meldonium is a cardiovascular drug, which is a synthetic compound originating from Latvia. It functions by modulating carnitine metabolism, leading to decreased fatty acid oxidation and augmented glucose oxidation. This shift in energy substrate helps to improve energy efficiency, particularly under conditions of ischemia, which can prevent ischemic damage by balancing oxygen supply and demand.

Formula: C₆H₁₄N₂O₂

Purezza: Min. 95 Area-%

Peso molecolare: 146.19 g/mol

Ref: 3D-Q-201406