CAS 76330-71-7

Altanserina

Descrizione:

Altanserina è un composto chimico riconosciuto principalmente per il suo ruolo di antagonista selettivo del recettore della serotonina 5-HT2A. Viene spesso utilizzato nella ricerca farmacologica, in particolare negli studi relativi alla neurofarmacologia e all'indagine dei disturbi psichiatrici. Il composto ha una struttura molecolare complessa, che contribuisce alla sua affinità di legame specifica per il recettore 5-HT2A, rendendolo uno strumento prezioso per comprendere le vie legate alla serotonina nel cervello. Altanserina è tipicamente caratterizzato dalla sua moderata lipofilia, che influisce sulla sua biodisponibilità e distribuzione all'interno dei sistemi biologici. Inoltre, è noto per le sue potenziali applicazioni negli studi di imaging, in particolare nella tomografia a emissione di positroni (PET) per visualizzare l'attività del recettore della serotonina. I profili di sicurezza e tossicità sono considerazioni essenziali nel suo utilizzo, come per qualsiasi agente farmacologico. In generale, Altanserina funge da composto importante sia in contesti terapeutici che di ricerca, contribuendo all'esplorazione del ruolo della serotonina in varie condizioni neurologiche e psichiatriche.

Formula: C₂₂H₂₂FN₃O₂S

InChI: InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)

InChI key: InChIKey=SMYALUSCZJXWHG-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(=S)N1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)=CC=CC2

Sinonimi:

• 278-422-1
• 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
• 3-{2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl}-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 4(1H)-quinazolinone, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-
• 76330-71-7
• Altanserin
• Altanserin hydrochloride hydrate
• 3-(2-(4-(4-Fluorobenzoyl)-1-piperidinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinonehydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrate hydrochloride
• AltanserineHCl
• ALTANSERIN HYDROCHLORIDE
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-2-THIOXO-4(1H)-QUINAZOLINONE HYDROCHLORIDE
• 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one
• Altanserin hydrate hydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride hydrate

altanserin hydrochloride

CAS: 76330-71-7

Formula: C₂₂H₂₂FN₃O₂S

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 411.4924

Ref: IN-DA0056E0

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

CAS: 76330-71-7

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

Purezza: 99%

Peso molecolare: 411.49g/mol

Ref: 54-PC108570

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Formula: C₂₂H₂₂FN₃O₂S·HCl·xH₂O

Peso molecolare: 447.95 (anhydrous)

Ref: 7W-GL6252

Altanserin

CAS: 76330-71-7

Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.

Formula: C₂₂H₂₂FN₃O₂S

Colore e forma: Solid

Peso molecolare: 411.49

Ref: TM-T29913

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Formula: C₂₂H₂₂FN₃O₂S•HCl•(H₂O)x

Purezza: Min. 95%

Ref: 3D-BA183187

Altanserin

Prodotto controllato

CAS: 76330-71-7

Formula: C₂₂H₂₂FN₃O₂S

Colore e forma: Neat

Peso molecolare: 411.492

Ref: TR-A585985

Altanserin

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Purezza: Min. 95%

Ref: 3D-FA41790