CAS 7640-51-9

10H-Fenotiazina-10-etanamina, N,N,α-trimetil-, 5-ossido

Descrizione:

10H-Fenotiazina-10-etanamina, N,N,α-trimetil-, 5-ossido, comunemente noto come un derivato della fenotiazina, è un composto chimico caratterizzato dalla sua struttura di base della fenotiazina, che consiste in una struttura eterociclica contenente zolfo e azoto. Questo composto tipicamente mostra proprietà come essere un solido a temperatura ambiente, con potenziali applicazioni in farmacologia, in particolare come agente antipsicotico o antistaminico grazie alla sua capacità di interagire con i sistemi di neurotrasmettitori. La presenza del gruppo trimetilammina migliora la sua solubilità e reattività, rendendolo utile in varie reazioni chimiche. Inoltre, la designazione 5-ossido indica la presenza di un atomo di azoto ossidato, che può influenzare le proprietà elettroniche e la reattività del composto. La sua struttura molecolare contribuisce alla sua attività biologica e può mostrare fluorescenza, rendendolo utile in chimica analitica. I dati di sicurezza devono essere consultati per la manipolazione e l'esposizione, come con tutte le sostanze chimiche, per garantire che vengano adottate le precauzioni appropriate.

Formula: C₁₇H₂₀N₂OS

InChI: InChI=1/C17H20N2OS/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)21(20)17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

InChI key: InChIKey=OWTCLFIFAFHQIX-UHFFFAOYSA-N

SMILES: C(C(N(C)C)C)N1C=2C(S(=O)C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• 10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide
• 10-(2-(Dimethylamino)propyl)-10H-phenothiazine5-oxide
• 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5-oxide
• 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, 5-oxide
• Diprazin sulfoxide
• N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine 5-oxide
• N-[2-(Dimethylamino)propyl]phenothiazine S-oxide
• Phenothiazine, 10-[2-(dimethylamino)propyl]-, 5-oxide
• Promethazine 5-oxide
• Promethazine 5-sulfoxide
• Promethazine sulfoxide
• Romergan sulfoxide
• ProMethazine EP IMpurity D
• N,N,α-TriMethyl-10H-phenothiazine-10-ethanaMine 5-Oxide
• Promethazine Impurity 4(Promethazine EP Impurity D)
• N,N,a-Trimethyl-10H-phenothiazine-10-ethanamine 5-Oxide
• Promethazine Impurity 4(EP Impurity D)
• Promethazine EP Impurity D Dihydrochloride
• PROMETHAZINE EP IMPURITY D (PROMETHAZINE SULFOXIDE)
• (2RS)-N,N-Dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine S-oxide
• N,N-dimethyl-1-(5-oxophenothiazin-10-yl)propan-2-amine

Promethazine EP Impurity D

CAS: 7640-51-9

Formula: C₁₇H₂₀N₂OS

Peso molecolare: 300.42

Ref: ST-EA-CP-P86004

Promethazine Sulphoxide 1.0 mg/ml in Methanol

CAS: 7640-51-9

Colore e forma: Single Solution

Ref: 61-AMP0412.04-01

Promethazine sulfoxide

CAS: 7640-51-9

Promethazine sulfoxide

Formula: C₁₇H₂₀N₂OS

Colore e forma: White Solid

Peso molecolare: 300.4185

Ref: 47-505

PROMETHAZINE IMPURITY D CRS

CAS: 7640-51-9

PROMETHAZINE IMPURITY D CRS

Ref: 41-Y0000769

Promethazine Sulfoxide

CAS: 7640-51-9

Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fused

Formula: C₁₇H₂₀N₂OS

Colore e forma: Grey Powder

Peso molecolare: 300.12963

Ref: 45-1A10030

10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide

CAS: 7640-51-9

Formula: C₁₇H₂₀N₂OS

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 300.4185

Ref: IN-DA008QHQ

Promethazine EP Impurity D (Promethazine Sulfoxide)

CAS: 7640-51-9

Formula: C₁₇H₂₀N₂OS

Colore e forma: White To Off-White Solid

Peso molecolare: 300.42

Ref: 4Z-P-181

10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide

CAS: 7640-51-9

10-(2-(Dimethylamino)propyl)-10H-phenothiazine 5-oxide

Purezza: 95%

Peso molecolare: 300.43g/mol

Ref: 54-OR1046044

Promethazine EP Impurity D

Prodotto controllato

CAS: 7640-51-9

Formula: C₁₇H₂₀N₂OS

Colore e forma: Neat

Peso molecolare: 300.42

Ref: 86-MM0412.04

Promethazine Sulfoxide

Prodotto controllato

CAS: 7640-51-9

Impurity Promethazine EP Impurity D
Applications Promethazine Sulfoxide (Promethazine EP Impurity D) is a metabolite of Promethazine (P757000).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gottschalk, L., et al.: J. Pharm. Sci., 67, 155 (1978), de Jongh, G., et al.: Drug Metab. Dispos., 9, 48 (1981), Hale, P., et al.: Toxicol. Appl. Pharmacol., 86, 44 (1986), Delbressine, L., et al.: Xenobiotica, 22, 227 (1992),

Formula: C₁₇H₂₀N₂OS

Colore e forma: Light Red To Purple

Peso molecolare: 300.42

Ref: TR-P757010

Promethazine sulfoxide

CAS: 7640-51-9

Promethazine sulfoxide is a phenothiazine derivative that is used in the treatment of allergies, colds, and motion sickness. It has been shown to inhibit peroxidases and reactions involving the production of hydrogen peroxide. Promethazine sulfoxide is metabolized by two pathways: one involving oxidation by cytochrome P450 enzymes and another involving hydrolysis by esterases or glucuronidases. The main metabolites are promethazine, promethazine sulfone, and N-methylpromethazine. When applied to urine samples, promethazine sulfoxide can be detected in concentrations of 1-10 ng/mL with an analytical method based on chromatography.

Formula: C₁₇H₂₀N₂OS

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 300.42 g/mol

Ref: 3D-FP27184

Promethazine Sulphoxide

CAS: 7640-51-9

Colore e forma: Neat

Ref: 61-FOR0412.04