CAS 765875-58-9

N-Deacylvaline Ritonavir (Thiazol-5-ylmethyl (2S,3S,5S)-5-[(S)-2-amino-3-methylbutanamido]-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate)

CAS: 765875-58-9

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

Formula: C₂₈H₃₆N₄O₄S

Peso molecolare: 524.24573

Ref: 45-1A13050

Ritonavir EP Impurity B HCl (Monoacyl Valine HCl)

CAS: 765875-58-9

Formula: C₂₈H₃₆N₄O₄S·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 524.68 36.46

Ref: 4Z-R-2712

[4-[(2-Amino-3-methyl-1-oxobutyl)amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic Acid 5-Thiazolylmethyl Ester

Prodotto controllato

CAS: 765875-58-9

Impurity Ritonavir EP Impurity D
Applications [4-[(2-Amino-3-methyl-1-oxobutyl)amino]-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-carbamic Acid 5-Thiazolylmethyl Ester, is an intermediate that can be used for the synthesis of Ritonavir (R535000), which is a selective HIV protease inhibitor.
References Daluge, S., et al.: Antimicrob. Agents Chemother., 38, 1590 (1994), Ammaranond, P., et al.: J. Clin. Virol., 26, 153 (2003), Harrigan, P., et al.: J. Infect. Dis., 191, 339 (2005), Miller, J., et al.: Bioorg. Med. Chem. Lett., 16, 1788(2006); Kempf, D., et al.: J. Med. Chem., 41, 602 (1998),

Formula: C₂₈H₃₆N₄O₄S

Colore e forma: Neat

Peso molecolare: 524.68

Ref: TR-A617010

Ritonavir EP Impurity B

CAS: 765875-58-9

Formula: C₂₈H₃₆N₄O₄S

Peso molecolare: 524.68

Ref: ST-EA-CP-R16002