CAS 76684-89-4

Acido loxistatinico

Descrizione:

Acido loxistatinico, con il numero CAS 76684-89-4, è un composto chimico che appartiene alla classe delle statine, conosciute principalmente per il loro ruolo nei farmaci per la riduzione del colesterolo. È caratterizzato dalla sua capacità di inibire la HMG-CoA reduttasi, un enzima cruciale nella biosintesi del colesterolo. Questa inibizione porta a una diminuzione dei livelli di colesterolo nel flusso sanguigno, rendendolo benefico per la gestione dell'iperlipidemia e per ridurre il rischio di malattie cardiovascolari. Acido loxistatinico è tipicamente un solido bianco o bianco sporco ed è solubile in solventi organici, ma la sua solubilità in acqua è limitata. Il composto può mostrare varie attività biologiche, comprese proprietà anti-infiammatorie e antiossidanti, che contribuiscono al suo potenziale terapeutico. Come molte statine, può avere effetti collaterali, tra cui dolore muscolare e alterazioni degli enzimi epatici, richiedendo monitoraggio durante l'uso. In generale, Acido loxistatinico rappresenta un significativo progresso nella farmacologia per la gestione della salute cardiovascolare.

Formula: C₁₅H₂₆N₂O₅

InChI: InChI=1/C15H26N2O5/c1-8(2)5-6-16-13(18)10(7-9(3)4)17-14(19)11-12(22-11)15(20)21/h8-12H,5-7H2,1-4H3,(H,16,18)(H,17,19)(H,20,21)/t10-,11-,12-/m0/s1

InChI key: InChIKey=SCMSYZJDIQPSDI-SRVKXCTJSA-N

SMILES: C(N[C@H](C(NCCC(C)C)=O)CC(C)C)(=O)[C@@H]1[C@@H](C(O)=O)O1

Sinonimi:

• (+)-(2S,3S)-3-((S)-3-Methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxiranecarboxylic acid
• (2S,3S)-3-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}carbamoyl)oxirane-2-carboxylic acid
• (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic acid
• 2-Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
• Brn 6688621
• E 64c
• EP 475 (Enzyme inhibitor)
• Ep 475
• Loxistatin acid
• NSC 694279
• Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2-alpha,3-beta(R*)))-
• Oxiranecarboxylic acid, 3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)amino)carbonyl)-, (2S-(2alpha,3beta(R*)))-
• Oxiranecarboxylic acid, 3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, (2S,3S)-
• Oxiranecarboxylic acid, 3-[[[3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-, [2S-[2α,3β(R*)]]-
• (2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
• (1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic
• anecarboxylicacid
• (2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE
• Loxistatin Acid (E-64C)
• (2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid
• E-64-c Loxistatin acid NSC 694279
• (L-3-TRANS-CARBOXYOXIRANE-2-CARBONYL)-L-LEUCINE (3-METHYLBUTYL)AMIDE
• (2S,3S)-3-[[(1S)-1-(3-Methylbutylcarbamoyl)-3-methylbutyl]carbamoyl]oxirane-2-carboxylic acid
• NSC 694279 Loxistatin Acid
• NSC 694279 LOXISTATIN ACID; EP 475;E64C;E 64C
• (2s-(2-alpha,3-beta(r*)))-mino)carbonyl)
• ep475(enzymeinhibitor)
• L-TRANS-EPOXYSUCCINYL-LEU-3-METHYLBUTYLAMIDE
• (+)-(2s,3s)-3-((s)-3-methyl-1-(3-methylbutylcarbamoyl)butylcarbamoyl)-2-oxir
• (2S,3S)-TRANS-EPOXYSUCCINYL-L-*LEUCYLAMI DO-3-METHYL
• oxiranecarboxylicacid,3-(((3-methyl-1-(((3-methylbutyl)amino)carbonyl)butyl)a
• Inhibitorforthiolprotease
• 2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-
• E-64c, EP 475

E-64c

CAS: 76684-89-4

Formula: C₁₅H₂₆N₂O₅

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 314.3773

Ref: IN-DA00G359

E 64c

CAS: 76684-89-4

E 64c

Purezza: ≥98%

Peso molecolare: 314.38g/mol

Ref: 54-BUP02992

E-64c Calpain Inhibitor

CAS: 76684-89-4

Formula: C₁₅H₂₆N₂O₅

Peso molecolare: 314.38

Ref: 7W-GL8757

E-64c

CAS: 76684-89-4

E-64c

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 314.38g/mol

Ref: 54-BIE1004

E 64c

CAS: 76684-89-4

E 64c (EP 475) , a derivative of E-64, is an irreversible and membrane-permeant cysteine protease inhibitor.

Formula: C₁₅H₂₆N₂O₅

Purezza: 98.73%

Colore e forma: Solid

Peso molecolare: 314.38

Ref: TM-T6573

(2S,3S)-3-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)oxirane-2-carboxylic acid

CAS: 76684-89-4

Purezza: ≥98%

Peso molecolare: 314.3819885

Ref: 10-F869543

E-64-c

CAS: 76684-89-4

E-64-c is a research tool that is used to activate the receptor of a cell. This ligand can bind to the receptor and form a complex, which will then be able to interact with other proteins in the cell. This process can lead to changes in ion channel activity, protein synthesis, or gene expression. E-64-c has been shown to inhibit the activity of ion channels such as calcium channels and potassium channels, as well as protein synthesis. It also binds to antibodies and blocks their binding sites on cells.br>
E-64-c is a high purity ligand that can be used for studying protein interactions or pharmacological purposes. The potency of this ligand has been tested by measuring its ability to inhibit the binding of various peptides such as vasopressin and angiotensin II.

Formula: C₁₅H₂₆N₂O₅

Purezza: Min. 95%

Peso molecolare: 314.38 g/mol

Ref: 3D-IEC-4320-V