CAS 7681-93-8

Natamicina

Descrizione:

Natamicina, noto anche come pimaricina, è un antibiotico macrolide polieno utilizzato principalmente come conservante naturale negli alimenti e come agente antifungino in varie applicazioni. È prodotto mediante fermentazione di alcune specie di Streptomyces. Natamicina è caratterizzato dalla sua capacità di inibire la crescita di un'ampia gamma di funghi e lieviti, rendendolo particolarmente efficace nel prevenire il deterioramento di prodotti lattiero-caseari, carni e prodotti da forno. Il composto agisce legandosi agli steroli nella membrana cellulare fungina, interrompendo l'integrità della membrana e portando alla morte cellulare. Natamicina è generalmente riconosciuto come sicuro (GRAS) per l'uso negli alimenti, e la sua efficacia è potenziata dalla sua bassa solubilità in acqua, che consente un'azione prolungata. Oltre alle sue applicazioni nella conservazione degli alimenti, Natamicina è utilizzato anche in ambito farmaceutico, in particolare nel trattamento delle infezioni fungine negli esseri umani e negli animali. La sua struttura chimica presenta un grande anello di lattone e più doppi legami coniugati, contribuendo alla sua attività biologica e stabilità in diverse condizioni.

Formula: C₃₃H₄₇NO₁₃

InChI: InChI=1/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6-,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32?,33-/m1/s1

InChI key: InChIKey=NCXMLFZGDNKEPB-FFPOYIOWSA-N

SMILES: C(O)(=O)[C@H]1[C@]2(O[C@@](O)(C[C@@H]1O)C[C@@H](O)C[C@@]3([C@](O3)(/C=C/C(=O)O[C@H](C)C\C=C\C=C\C=C\C=C\[C@H](O[C@H]4[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O4)C2)[H])[H])[H]

Sinonimi:

• (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-Amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• (1R,3S,5R,7R,8E,12R,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• (8Z,14Z,16Z,18Z,20Z)-22-[(3-amino-3,6-dideoxyhexopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• 22-[(3-amino-3,6-dideoxy-beta-D-glycero-hexopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-
• 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-
• 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-
• 6,11,28-Trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-
• 6,11,28-Trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-
• 6,11,28-Trioxatricyclo[22.3.1.0^5,7]octacosane, pimaricin deriv.
• Antibiotic A 5283
• Cl 12625
• Delvocid
• E 235
• Mycophyt
• Myprozine
• Myuprozine
• Natacyn
• Natajen
• Natamatrix
• Natamax
• Natamax SF
• Natamax lactose
• Natamicina
• Natamycin
• Natamycin Sterile
• Natamycine
• Pimaricin
• Pimaricin, Streptomyces chattanoogensis (1.07360)
• Synogil
• Tennecetin
• [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• δ-Natamycin

Natamycin, 95%

CAS: 7681-93-8

Natamycin, 7681-93-8, also known as pimaricin, is a polyene macrolide antibiotic isolated from Streptomyces natalensis which exhibits antifungal properties. Learn more.

Formula: C₃₃H₄₇NO₁₃

Purezza: 95%

Colore e forma: White to pale yellow to pale brown, Powder or crystals

Peso molecolare: 665.73

Ref: 02-J66468

Natamycin

CAS: 7681-93-8

Antibiotics nesoi

Formula: C₃₃H₄₇NO₁₃

Colore e forma: Off-White Cream Powder

Peso molecolare: 665.30474

Ref: 45-1457505

Natamycin

CAS: 7681-93-8

Natamycin (Pimaricin) is a Polyene Antimicrobial.

Formula: C₃₃H₄₇NO₁₃

Purezza: 98.73%

Colore e forma: White To Creamy-White Crystalline Powder

Peso molecolare: 665.73

Ref: TM-T0709

6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid,22-[(3-amino-3,6-dideoxy-b-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-,(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-

CAS: 7681-93-8

Formula: C₃₃H₄₇NO₁₃

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 665.7252

Ref: IN-DA00IKIX

Pimaricin

CAS: 7681-93-8

Pimaricin

Formula: C₃₃H₄₇NO₁₃

Colore e forma: off white to faint yellow powder

Peso molecolare: 665.73g/mol

Ref: 54-BIP0144

Natamycin

CAS: 7681-93-8

Natamycin

Purezza: ≥95%

Peso molecolare: 665.73g/mol

Ref: 54-BUP15815

Natamycin

CAS: 7681-93-8

Formula: C₃₃H₄₇NO₁₃

Peso molecolare: 665.73

Ref: 4Z-N-158001

Pimaricin

CAS: 7681-93-8

Formula: C₃₃H₄₇NO₁₃

Purezza: ≥ 95.0% (dried basis)

Colore e forma: White to yellow powder

Peso molecolare: 665.7

Ref: 7W-GA5100

Pimaricin

Prodotto controllato

CAS: 7681-93-8

Formula: C₃₃H₄₇NO₁₃

Colore e forma: Neat

Peso molecolare: 665.73

Ref: 04-C16208400

Natamycin RS

CAS: 7681-93-8

Colore e forma: White To Yellow-White Solid Crystalline Powder

Ref: 2K-5015000021

Natamycin

CAS: 7681-93-8

Stability Hygroscopic, Light Sensitive
Applications Polyene antifungal antibiotic.
References Levinskas, G.J., et al.: Toxicol. Appl. Pharmacol., 8, 97 (1966), Pandey, R.C., et al.: J. Antibiot., 29, 1035 (1976), Brik, H., et al.: Anal. Profiles Drug Subs. Excip., 23, 399 (1994),

Formula: C₃₃H₄₇NO₁₃

Colore e forma: White To Light Beige

Peso molecolare: 665.73

Ref: TR-N379100

Natamycin (NAT) extrapure, 90-102%

CAS: 7681-93-8

Formula: C₃₃H₄₇NO₁₃

Peso molecolare: 665.73

Ref: SR-36059

NATAMYCIN

CAS: 7681-93-8

Purezza: 96%

Peso molecolare: 665.7329712

Ref: 10-F806751

Natamycin

CAS: 7681-93-8

Natamycin is a polyene macrolide antifungal agent with action on fungal cell membranes by binding to sterols and is used for treating fungal infections and as a food preservative.

Formula: C₃₃H₄₇NO₁₃

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 665.73 g/mol

Ref: 3D-AN26164