CAS 769-42-6

Acido dimetilbarbiturico

Descrizione:

Acido dimetilbarbiturico, con il numero CAS 769-42-6, è un composto chimico che appartiene alla classe dei farmaci barbiturici, che sono derivati dell'acido barbiturico. È caratterizzato dalla sua struttura, che include due gruppi metilici attaccati agli atomi di azoto della struttura dell'acido barbiturico. Questo composto è tipicamente un solido cristallino bianco che è solubile in acqua ed espone proprietà debolmente acide a causa della presenza di gruppi funzionali di acido carbossilico. Acido dimetilbarbiturico è noto per i suoi effetti sedativi e ipnotici, sebbene sia meno comunemente usato in contesti clinici rispetto ad altri barbiturici. La sua attività farmacologica è attribuita alla sua capacità di modulare l'attività del neurotrasmettitore acido gamma-aminobutirrico (GABA) al recettore GABA-A, portando a una depressione del sistema nervoso centrale. Inoltre, ha applicazioni nella ricerca biochimica e come intermediario nella sintesi organica. Le precauzioni di sicurezza e gestione sono essenziali a causa del suo potenziale di tossicità e dipendenza.

Formula: C₆H₈N₂O₃

InChI: InChI=1/C6H8N2O3/c1-7-4(9)3-5(10)8(2)6(7)11/h3H2,1-2H3

InChI key: InChIKey=VVSASNKOFCZVES-UHFFFAOYSA-N

SMILES: CN1C(=O)N(C)C(=O)CC1=O

Sinonimi:

• 1,3-Dimethyl-1,3-diazacyclohexane-2,4,6-trione
• 1,3-Dimethyl-1,3-diazinane-2,4,6-trione
• 1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
• 1,3-Dimethyl-pyrimidine-2,4,6-trione
• 1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dimethyl-
• 6-Hydroxy-1,3-dimethyluracil
• Barbituric acid, 1,3-dimethyl-
• Dimethylbarbituric acid
• N,N'-Dimethylbarbituric acid
• N,N′-Dimethyl-2,4,6-pyrimidinetrione
• Nsc 61918
• 1,3-Dimethylbarbituric acid
• 1,3-Dimethylpyrimidine-2,4,6(1H,2H,5H)-trione
• 1,3-Dimethylhexahydropyrimidine-2,4,6-trione
• AKOS B029702
• 1,3-Dimethylbarbituric acid, 99% (dry wt.) water < 6%
• Hexahydro-1,3-dimethylpyrimidine-2,4,6-trione
• 1,3-dimethyl-4,6(1h,3h,5h)-pyrimidinetrione
• 1,3-Dimethyl-2,4,6-Trihydroxy-Pyrimidine
• 6(1h,3h,5h)-pyrimidinetrione,1,3-dimethyl-4

1,3-Dimethylbarbituric acid, 99% (dry wt.), water &lt;6%

CAS: 769-42-6

1,3-Dimethylbarbituric acid is used as a catalyst in the Knoevenagel condensation of a series of aromatic aldehydes. It is also used in the synthesis of 5-aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives and enantioselective synthesis of isochromene pyrimidinedione deriva

Formula: C₆H₈N₂O₃

Purezza: 99%

Colore e forma: White to cream or pale yellow, Crystals or powder or crystalline powder

Peso molecolare: 156.14

Ref: 02-A13692

1,3-Dimethylbarbituric acid

CAS: 769-42-6

Formula: C₆H₈N₂O₃

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 156.1393

Ref: IN-DA003DKC

1,3-Dimethylbarbituric acid

CAS: 769-42-6

Formula: C₆H₈N₂O₃

Purezza: ≥ 99.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 156.14

Ref: 7W-GX0205

1,3-Dimethylbarbituric acid

CAS: 769-42-6

1,3-Dimethylbarbituric acid

Purezza: 99%

Peso molecolare: 156.14g/mol

Ref: 54-OR1002579

Urapidil Impurity 4 (1,3-Dimethylbarbituric Acid)

CAS: 769-42-6

Formula: C₆H₈N₂O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 156.14

Ref: 4Z-U-0710

1,3-Dimethylbarbituric Acid

CAS: 769-42-6

Formula: C₆H₈N₂O₃

Purezza: >98.0%(GC)(T)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 156.14

Ref: 3B-D1618

1,3-Dimethylbarbituric Acid

CAS: 769-42-6

Colore e forma: Neat

Ref: 86-MM3980.05

1,3-Dimethyl Barbituric Acid

Prodotto controllato

CAS: 769-42-6

Applications 1,3-Dimethyl Barbituric Acid (Urapidil Impurity 4) is a derivative of Barbituric acid (B118650). All of the barbituric acid derivatives which have been reported to have pronounced hypnotic activity are disubstituted in the 5-position.
References Gupta, K., et al.: Eur. J. Med. Chem., 17, 448 (1982), Weber, L., et al.: Curr. Med. Chem., 9, 2085 (2002), Skiles, J., et al.: Curr. Med. Chem., 11, 2911 (2004),

Formula: C₆H₈N₂O₃

Colore e forma: Neat

Peso molecolare: 156.14

Ref: TR-D463650

1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione

Prodotto controllato

CAS: 769-42-6

1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione is a heterocyclic organic compound, which is synthesized via established chemical procedures involving catalytic methods or direct condensation reactions. This compound is well-known for its role in the biochemical field as a urease inhibitor. Urease, an enzyme that catalyzes the hydrolysis of urea, is targeted by this compound to potentially mitigate issues related to excessive ammonia production in agricultural and medical settings.In addition to its enzymatic inhibition properties, 1,3-Dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione serves as a pivotal intermediate in barbiturate synthesis. Barbiturates are psychoactive compounds used historically in medicine for their sedative and anesthetic properties. The compound's structure allows it to participate in the Knoevenagel condensation, facilitating the formation of complex molecules essential in pharmaceutical development. These multifunctional applications make it a valuable tool in various scientific research contexts, exploring both inhibitory mechanisms and synthetic pathways for drug discovery and development.

Formula: C₆H₈N₂O₃

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 156.14 g/mol

Ref: 3D-FD128015

1,3-Dimethylbarbituric acid

CAS: 769-42-6

Formula: C₆H₈N₂O₃

Purezza: 98.0%

Peso molecolare: 156.141

Ref: 10-F078986

Urapidil Impurity 4

CAS: 769-42-6

Formula: C₆H₈N₂O₃

Peso molecolare: 156.14

Ref: ST-EA-CP-U2004