CAS 77307-50-7

Kaempferol 3-O-(3′′,4′′-di-O-acetil-α-L-ramnopiranoside)

Descrizione:

Kaempferol 3-O-(3′′,4′′-di-O-acetil-α-L-ramnopiranoside) è un glicoside flavonoide, una sottoclasse di flavonoidi nota per le sue proprietà antiossidanti. Questo composto presenta una struttura di base di kaempferolo, che è un flavonolo, ed è modificato dalla presenza di un moiety di zucchero rhamnosio che è ulteriormente acetilato in due posizioni. L'acetilazione migliora la sua solubilità e stabilità, influenzando potenzialmente la sua attività biologica. I derivati del kaempferolo sono spesso studiati per i loro potenziali benefici per la salute, inclusi effetti anti-infiammatori, anticancerogeni e cardioprotettivi. La presenza dell'unità rhamnopyranoside può anche contribuire alla sua bioattività e interazione con i sistemi biologici. Questo composto si trova tipicamente in varie piante, in particolare in frutta e verdura, ed è di interesse nella farmacognosia e nella chimica dei prodotti naturali. Il suo numero CAS, 77307-50-7, consente un'identificazione precisa in banche dati chimiche e nella letteratura. In generale, Kaempferol 3-O-(3′′,4′′-di-O-acetil-α-L-ramnopiranoside) esemplifica l'interazione complessa tra struttura e funzione nei prodotti naturali.

Formula: C₂₅H₂₄O₁₂

InChI: InChI=1/C25H24O12/c1-10-21(34-11(2)26)24(35-12(3)27)20(32)25(33-10)37-23-19(31)18-16(30)8-15(29)9-17(18)36-22(23)13-4-6-14(28)7-5-13/h4-10,20-21,24-25,28-30,32H,1-3H3/t10-,20+,21?,24?,25?/m0/s1

InChI key: InChIKey=SXOZSDJHGMAEGZ-IGKKHSBFSA-N

SMILES: O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC=C(O)C=C3)[C@H]4[C@H](O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](C)O4

Sinonimi:

• 3-[(3,4-Di-O-acetyl-6-deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• 3′′,4′′-Di-O-acetylafzelin
• 4H-1-Benzopyran-4-one, 3-[(3,4-di-O-acetyl-6-deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-
• Kaempferol 3-O-(3′′,4′′-di-O-acetyl-α-<span class="text-smallcaps">L</span>-rhamnopyranoside)
• Sl 0101
• Sl 0101-1
• Sl0101
• 4H-1-Benzopyran-4-one, 3-[(3,4-di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-
• 3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
• Kaempferol 3-O-(3′′,4′′-di-O-acetyl-α-L-rhamnopyranoside)
• 2-(4-Hydroxyphenyl)-4-oxo-5,7-dihydroxy-4H-1-benzopyran-3-yl 3-O,4-O-diacetyl-α-L-rhamnopyranoside
• 2-(4-Hydroxyphenyl)-3-(3-O,4-O-diacetyl-α-L-rhamnopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one
• 3'',4''-Di-O-acetylafzelin
• Kaempferol 3-O-(3'',4''-di-O-acetyl-alpha-L-rhamnopyranoside)
• 3-[(3,4-Di-O-acetyl-6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydro-2-(4-hydroxyphenyl)-4H-1benzopyran-4-one
• 3-[(3-O,4-O-Diacetyl-6-deoxy-α-L-mannopyranosyl)oxy]4',5,7-trihydroxyflavone

SL 0101-1

CAS: 77307-50-7

SL0101: selective, reversible ATP-competitive RSK inhibitor, membrane-permeable, IC50=89nM, potent RSK1/2 inhibitor, Ki=1μM.

Formula: C₂₅H₂₄O₁₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 516.45

Ref: TM-T16896

Sl0101

CAS: 77307-50-7

Sl0101

Peso molecolare: 516.45085g/mol

Ref: 54-BISN0307

SL0101

Prodotto controllato

CAS: 77307-50-7

Applications SL 0101 is a potent and selective inhibitor of p90 Rsk, without inhibiting the function of upstream kinases such as MEK, Raf, or PKC.
References Maloney, D.J. and Hecht, S.M.: Organic Letters, 7, 6, 1097 (2005)

Formula: C₂₅H₂₄O₁₂

Colore e forma: Neat

Peso molecolare: 516.45

Ref: TR-S560000

SL 0101-1

CAS: 77307-50-7

SL 0101-1 is a transcriptional regulator that regulates the expression of genes and proteins. It belongs to the family of inhibitors, which are pharmacological agents that inhibit the activity of other drugs or enzymes. This compound is an inhibitor of protein kinase A (PKA) and protein kinase C (PKC). These enzymes regulate cellular processes such as cell growth, differentiation, and survival. SL 0101-1 has been shown to induce mitochondrial membrane depolarization, neuronal death, and inhibition of DNA polymerase activity in cancer tissues. In addition, it inhibits the binding of a nuclear factor to DNA and phosphorylation in neuronal cells.
SL 0101-1 also has anti-inflammatory properties by inhibiting cyclooxygenase-2 (COX-2), which is responsible for production of prostaglandins.

Formula: C₂₅H₂₄O₁₂

Purezza: Min. 95%

Peso molecolare: 516.46 g/mol

Ref: 3D-CDA30750