CAS 77377-52-7

N-Metil-N-(tert-butil-dimetilsilil)trifluoroacetamide

Descrizione:

N-Metil-N-(tert-butil-dimetilsilil)trifluoroacetamide, con il numero CAS 77377-52-7, è un composto chimico comunemente utilizzato nella sintesi organica e nella chimica analitica, in particolare nella derivatizzazione di ammine e alcoli per la cromatografia gascromatografica. Questo composto presenta un gruppo funzionale trifluoroacetamide, che migliora la volatilità e la stabilità termica, rendendolo adatto per l'analisi in fase gassosa. La presenza del gruppo tert-butyldimethylsilyl fornisce protezione sterica e aumenta la lipofilia della molecola, facilitando la separazione e la rilevazione degli analiti target. N-Metil-N-(tert-butil-dimetilsilil)trifluoroacetamide è tipicamente un liquido incolore o giallo pallido con un odore caratteristico. È solubile in solventi organici ed è stabile in condizioni di laboratorio standard. Tuttavia, come molti derivati del silyl, può idrolizzarsi in presenza di umidità, rilasciando alcoli di silyl. Devono essere adottate precauzioni di sicurezza quando si maneggia questo composto, poiché può comportare rischi per la salute se inalato o ingerito. Si raccomanda di conservarlo in un luogo fresco e asciutto per mantenere la sua integrità.

Formula: C₉H₁₈F₃NOSi

InChI: InChI=1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

InChI key: InChIKey=QRKUHYFDBWGLHJ-UHFFFAOYSA-N

SMILES: N([Si](C(C)(C)C)(C)C)(C(C(F)(F)F)=O)C

Sinonimi:

• Acetamide, N-[(1,1-dimethylethyl)dimethylsilyl]-2,2,2-trifluoro-N-methyl-
• N-(Tertbutyldimethylsilyl)-N-methyltrifluoroacetamide
• N-(t-butyldimethylsilyl)-N-Methyl-trifluoroacetamide
• N-Methyl-N-(tert-butyldimethylsilyl)-1,1,1-trifluoroacetamide
• N-Methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide
• N-Methyl-N-(tert-butyltdimethylsilyl)trifluoroacetamide
• N-[(1,1-Dimethylethyl)dimethylsilyl]-2,2,2-trifluoro-N-methylacetamide
• N-[butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
• N-methyl-N-(t-butyldimethylsilyl)trifluoroacetamide
• N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide

N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide

CAS: 77377-52-7

Formula: C₉H₁₈F₃NOSi

Purezza: >95.0%(GC)

Colore e forma: Colorless to Almost colorless clear liquid

Peso molecolare: 241.33

Ref: 3B-B1150

N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide, 97%

CAS: 77377-52-7

It finds its application in the preparation of N-tert-butyldimethylsilyl ethanolamines resulting from hydrolysis of nitrogen mustards and a silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatography-mass spectrometry (GC-MS) analysis and sel

Formula: C₉H₁₈F₃NOSi

Purezza: 97%

Colore e forma: Clear colorless to pale yellow, Liquid

Peso molecolare: 241.33

Ref: 02-B23760

N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide

CAS: 77377-52-7

Formula: C₉H₁₈F₃NOSi

Purezza: 95%

Colore e forma: Liquid

Peso molecolare: 241.3260

Ref: IN-DA0036J3

N-[(tert-Butyl)dimethylsilyl]-N-methyltrifluoroacetamide

CAS: 77377-52-7

N-[(tert-Butyl)dimethylsilyl]-N-methyltrifluoroacetamide

Formula: C₉H₁₈F₃NOSi

Purezza: 98%

Colore e forma: clear. colourless liquid

Peso molecolare: 241.33g/mol

Ref: 54-PC5157

N-(tert-Butyldimethylsilyl)-N-methyl trifluoroacetamide

CAS: 77377-52-7

Formula: C₉H₁₈F₃NOSi

Purezza: ≥ 96.0%

Colore e forma: Clear, colourless liquid

Peso molecolare: 241.33

Ref: 7W-GK4999

N-[(tert-Butyl)dimethylsilyl]-N-methyltrifluoroacetamide

CAS: 77377-52-7

N-[(tert-Butyl)dimethylsilyl]-N-methyltrifluoroacetamide

Formula: C₉H₁₈F₃NOSi

Purezza: 95%

Colore e forma: clear. almost colourless liquid

Peso molecolare: 241.32602g/mol

Ref: 54-PC0406

N-Methyl-N-(tert-butyldimethylsilyl)trifluoro-acetamide

CAS: 77377-52-7

S11050 - N-Methyl-N-(tert-butyldimethylsilyl)trifluoro-acetamide

Formula: C₉H₁₈F₃NOSi

Purezza: 95%

Colore e forma: Liquid, Clear

Peso molecolare: 241.329

Ref: 10-S11050

N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide (Technical Grade)

CAS: 77377-52-7

Applications A silylating agent used in the derivatization of various organic compounds (such as amino acids) for gas chromatogography-mass spectrometry (GC-MS) analysis.
References Pleasance, S. et al.: Biomed. Env. Mass Spec., 19, 420 (1990); Paik, M. et al.: BMB Rep., 41, 23 (2008);

Formula: C₉H₁₈F₃NOSi

Colore e forma: Neat

Peso molecolare: 241.33

Ref: TR-B691310

N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide

CAS: 77377-52-7

N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide is an analytical method for measuring the concentration of hydrogen fluoride in human serum. It is used as a reagent to extract metabolic compounds from wastewater and to measure the quantity of chlorogenic acids in plant leaves. This compound is also used as a reagent for gas chromatography/mass spectrometry analysis of the aromatic amines, which are carcinogens. N-(tert-Butyldimethylsilyl)-N-methyltrifluoroacetamide has been shown to inhibit proliferation of HL-60 cells, which are derived from a myeloid leukemia cell line, and colon cancer cell lines. This compound has been shown to be effective against colon cancer cells through its ability to induce apoptosis.

Formula: C₉H₁₈F₃NOSi

Purezza: Min. 97%

Colore e forma: Colorless Clear Liquid

Peso molecolare: 241.33 g/mol

Ref: 3D-FB19530