CAS 78110-38-0
:Aztreonam
Descrizione:
Aztreonam è un antibiotico monobattamico sintetico utilizzato principalmente per trattare infezioni causate da batteri Gram-negativi. È caratterizzato dalla sua struttura beta-lattamica, essenziale per la sua attività antibatterica. Aztreonam è particolarmente efficace contro Pseudomonas aeruginosa e altre Enterobacteriaceae, rendendolo un'opzione preziosa per i pazienti con allergie alla penicillina, poiché ha una bassa reattività crociata con le penicilline. Il composto viene tipicamente somministrato per via endovenosa o intramuscolare, poiché non viene ben assorbito se assunto per via orale. Aztreonam presenta un meccanismo d'azione unico inibendo la sintesi della parete cellulare batterica, portando alla lisi cellulare e alla morte. La sua stabilità contro alcune beta-lattamasi, enzimi prodotti dai batteri per conferire resistenza, ne aumenta l'efficacia nel trattamento di infezioni resistenti. Inoltre, Aztreonam ha un profilo farmacocinetico favorevole, con una emivita relativamente breve e una buona penetrazione nei tessuti, consentendo un trattamento efficace di varie infezioni. Tuttavia, come tutti gli antibiotici, può causare effetti collaterali, inclusi disturbi gastrointestinali e potenziali reazioni allergiche.
Formula:C13H17N5O8S2
InChI:InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
InChI key:InChIKey=WZPBZJONDBGPKJ-VEHQQRBSSA-N
SMILES:N(C(/C(=N\OC(C(O)=O)(C)C)/C1=CSC(N)=N1)=O)[C@H]2[C@H](C)N(S(=O)(=O)O)C2=O
Sinonimi:- (2S,3S)-3-({(2E)-2-(2-ammonio-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-2-methyl-4-oxoazetidine-1-sulfonate
- (2S-(2-Alpha,3-Beta(Z)))-Dinyl)Amino)-2-Oxoethylidene)Amino)Oxy)-2-Methyl
- 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
- 2-({[1-(2-amino-1,3-thiazol-4-yl)-2-{[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino}-2-oxoethylidene]amino}oxy)-2-methylpropanoic acid
- 2-[({(1E)-1-(2-amino-1,3-thiazol-4-yl)-2-[(2-methyl-4-oxo-1-sulfoazetidin-3-yl)amino]-2-oxoethylidene}amino)oxy]-2-methylpropanoic acid
- 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
- Antibiotic Squibb 26,776
- Azonam
- Azthreonam
- Aztreon
- Aztreonamo
- Monobactam
- Nebactam
- Primbactam
- Propanoic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-
- Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2R-[2α,3α(Z)]]-
- Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2S-[2α,3β(Z)]]-
- Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2α,3β(Z)]-
- Sq 26776
- Squibb 26776
- Vedi altri sinonimi
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15 prodotti.
Aztreonam
CAS:Formula:C13H17N5O8S2Purezza:>98.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:435.43Aztreonam
CAS:<p>Aztreonam is used to treat severe infections of the urinary tract, lower respiratory tract, skin, stomach, female reproductive organs, and other body systems. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label informat</p>Formula:C13H17N5O8S2Colore e forma:White to yellow crystalline powderPeso molecolare:435.43Aztreonam
CAS:Antibiotics nesoiFormula:C13H17N5O8S2Colore e forma:White Off-White Crystalline PowderPeso molecolare:435.051852-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxy-2-methylpropanoic acid
CAS:Formula:C13H17N5O8S2Purezza:90%Colore e forma:SolidPeso molecolare:435.4328Aztreonam
CAS:Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.Formula:C13H17N5O8S2Purezza:97.6% - >99.99%Colore e forma:SolidPeso molecolare:435.43Aztreonam
CAS:Formula:C13H17N5O8S2Purezza:95.0 - 105.0 % (dried basis)Colore e forma:White to off-white crystalline powderPeso molecolare:435.43Aztreonam, USP grade
CAS:Formula:C13H17N5O8S2Purezza:≤ 1.5%Colore e forma:White to off-white crystalline powderPeso molecolare:435.43Aztreonam
CAS:Prodotto controllato<p>Applications The first totally synthetic monocyclic β-lactam antibiotic.<br>References Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982), Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988),<br></p>Formula:C13H17N5O8S2Colore e forma:WhitePeso molecolare:435.43Aztreonam
CAS:<p>A β-lactam antibiotic of monobactam subclass, which targets peptidoglycan synthesis in bacterial cell wall. Aztreonam is effective against Gram-negative aerobic bacteria and is more resistant to β-lactamases than other β-lactam antibiotics.</p>Formula:C13H17N5O8S2Purezza:Min. 97 Area-%Colore e forma:White Off-White PowderPeso molecolare:435.43 g/molAztreonam (AZN), 96%
CAS:Formula:C13H17N5O8S2Purezza:min. 96.0%Colore e forma:White to light yellow, Powder, Clear, Colourless to pale yellowPeso molecolare:435.43Aztreonam, Antibiotic for Culture Media Use Only
CAS:<p>Please enquire for more information about Aztreonam, Antibiotic for Culture Media Use Only including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C13H17N5O8S2Purezza:94 To 102%Peso molecolare:435.43 g/molRef: 3D-A-9950
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![2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethy…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IKH2.jpg&w=3840&q=75)
