CAS 78111-17-8

acido 1,7-diossaspirano[5.5]undec-10-ene-2-propanoico, α,5-diidrossi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-ottaidro-8'-idrossi-6'-[(1S,3S)-1-idrossi-3-[(2S,3R,6S)-3-metil-1,7-diossaspirano[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)-

Descrizione:

acido 1,7-diossaspirano[5.5]undec-10-ene-2-propanoico, α,5-diidrossi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-ottaidro-8'-idrossi-6'-[(1S,3S)-1-idrossi-3-[(2S,3R,6S)-3-metil-1,7-diossaspirano[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)- è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come dioxaspiro, idrossile e moieties di acido propanoico. Questo composto presenta chiralità, indicata dai suoi descrittori stereochimici, suggerendo che può esistere in più forme enantiomeriche. La sua complessità strutturale può conferire proprietà chimiche uniche, influenzando potenzialmente la sua reattività e le interazioni con i sistemi biologici. La presenza di più anelli e centri stereogenici suggerisce che potrebbe avere applicazioni in ambito farmaceutico o come intermedio sintetico in chimica organica. Inoltre, il numero CAS del composto, 78111-17-8, consente una facile identificazione e riferimento nelle banche dati chimiche. In generale, questa sostanza rappresenta un esempio affascinante della sintesi organica moderna e della diversità strutturale nei composti chimici.

Formula: C₄₄H₆₈O₁₃

InChI: InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1

InChI key: InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N

SMILES: O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1

Sinonimi:

• (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
• 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
• 35-Demethyl-DTX 1
• 35-Demethyldinophysistoxin 1
• Acanthifolicin, 9,10-deepithio-9,10-didehydro-
• Nsc 677083
• Okadaic acid
• Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
• (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
• 78111-17-8
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
• OKADAIC ACID, 25 UG*
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
• Okadaic acid, free acid >98%
• Okadic acid
• OA
• OKADAIC ACID >95% PROTEIN PHOSPHATASE I
• 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
• OKADAIC ACID FREE ACID
• Okadaic acid,97%
• OKADAICACID,HIGHPURITY
• 9,10-deepithio-9,10-didehydro-acanthifolici
• OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
• OKADAIC ACID, 98+%
• OKADAIC ACID, PROROCENTRUM CONCAVUM
• Ocadaic Acid
• HALOCHONDRINE A
• Okadaic acid from Prorocentrum concavum,OA
• Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
• OKADAIC ACID SODIUM SALT 98+%
• Blue mussel, homogenized (Okadaic acid)
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
• OKADAIC ACID FROM PROROCENTRUM SP.
• 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
• Okadaicacid,Prorocentrumconcavum,highpurity

Okadaic acid, 98%

CAS: 78111-17-8

Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junct

Formula: C₄₄H₆₈O₁₃

Purezza: 98%

Colore e forma: White, Solid

Peso molecolare: 805.02

Ref: 02-J60155

Okadaic acid

CAS: 78111-17-8

Formula: C₄₄H₆₈O₁₃

Colore e forma: Solid

Peso molecolare: 805.0029

Ref: IN-DA003AXF

Okadaic acid, Prorocentrum concavum, high purity

CAS: 78111-17-8

Formula: C₄₄H₆₈O₁₃

Purezza: >98%

Peso molecolare: 805.015

Ref: 10-M02211

Okadaic acid

CAS: 78111-17-8

Formula: C₄₄H₆₈O₁₃

Purezza: ≥ 97.0%

Colore e forma: White crystalline powder or solid

Peso molecolare: 805.02

Ref: 7W-GL7691

Okadaic acid, free acid

CAS: 78111-17-8

Okadaic acid, free acid

Formula: C₄₄H₆₈O₁₃

Purezza: >98%

Colore e forma: white lyophilized solid

Peso molecolare: 805.00g/mol

Ref: 54-BIM1576

Okadaic Acid

CAS: 78111-17-8

Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);

Formula: C₄₄H₆₈O₁₃

Colore e forma: Neat

Peso molecolare: 805.00

Ref: TR-O515500

Okadaic acid

CAS: 78111-17-8

Inhibitor of PP1 and PP2A protein phosphatases

Formula: C₄₄H₆₈O₁₃

Purezza: Min. 95%

Peso molecolare: 805 g/mol

Ref: 3D-FO73140

Okadaic acid

CAS: 78111-17-8

Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.

Formula: C₄₄H₆₈O₁₃

Purezza: 98%

Colore e forma: White Crystals Or Powder

Peso molecolare: 805

Ref: TM-T16381