![1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F386020-okadaic-acid.webp&w=3840&q=75)
CAS 78111-17-8
:acido 1,7-diossaspirano[5.5]undec-10-ene-2-propanoico, α,5-diidrossi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-ottaidro-8'-idrossi-6'-[(1S,3S)-1-idrossi-3-[(2S,3R,6S)-3-metil-1,7-diossaspirano[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)-
Descrizione:
acido 1,7-diossaspirano[5.5]undec-10-ene-2-propanoico, α,5-diidrossi-α,10-dimetil-8-[(1R,2E)-1-metil-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-ottaidro-8'-idrossi-6'-[(1S,3S)-1-idrossi-3-[(2S,3R,6S)-3-metil-1,7-diossaspirano[5.5]undec-2-il]butil]-7'-metilenespiro[furan-2(3H),2'(3'H)-pirano[3,2-b]pirano]-5-il]-2-propenil]-, (αR,2S,5R,6R,8S)- è un composto organico complesso caratterizzato dalla sua intricatissima struttura molecolare, che include più gruppi funzionali come dioxaspiro, idrossile e moieties di acido propanoico. Questo composto presenta chiralità, indicata dai suoi descrittori stereochimici, suggerendo che può esistere in più forme enantiomeriche. La sua complessità strutturale può conferire proprietà chimiche uniche, influenzando potenzialmente la sua reattività e le interazioni con i sistemi biologici. La presenza di più anelli e centri stereogenici suggerisce che potrebbe avere applicazioni in ambito farmaceutico o come intermedio sintetico in chimica organica. Inoltre, il numero CAS del composto, 78111-17-8, consente una facile identificazione e riferimento nelle banche dati chimiche. In generale, questa sostanza rappresenta un esempio affascinante della sintesi organica moderna e della diversità strutturale nei composti chimici.
Formula:C44H68O13
InChI:InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1
InChI key:InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N
SMILES:O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1
Sinonimi:- (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
- 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
- 35-Demethyl-DTX 1
- 35-Demethyldinophysistoxin 1
- Acanthifolicin, 9,10-deepithio-9,10-didehydro-
- Nsc 677083
- Okadaic acid
- Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
- (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
- 78111-17-8
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
- OKADAIC ACID, 25 UG*
- 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
- Okadaic acid, free acid >98%
- Okadic acid
- OA
- OKADAIC ACID >95% PROTEIN PHOSPHATASE I
- 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
- 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
- OKADAIC ACID FREE ACID
- Okadaic acid,97%
- OKADAICACID,HIGHPURITY
- 9,10-deepithio-9,10-didehydro-acanthifolici
- OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
- OKADAIC ACID, 98+%
- OKADAIC ACID, PROROCENTRUM CONCAVUM
- Ocadaic Acid
- HALOCHONDRINE A
- Okadaic acid from Prorocentrum concavum,OA
- Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
- OKADAIC ACID SODIUM SALT 98+%
- Blue mussel, homogenized (Okadaic acid)
- 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
- OKADAIC ACID FROM PROROCENTRUM SP.
- 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
- Okadaicacid,Prorocentrumconcavum,highpurity
- Vedi altri sinonimi
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8 prodotti.
Okadaic acid, 98%
CAS:Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junctFormula:C44H68O13Purezza:98%Colore e forma:White, SolidPeso molecolare:805.02Okadaic acid, Prorocentrum concavum, high purity
CAS:Formula:C44H68O13Purezza:>98%Peso molecolare:805.015Okadaic acid
CAS:Formula:C44H68O13Purezza:≥ 97.0%Colore e forma:White crystalline powder or solidPeso molecolare:805.02Okadaic acid, free acid
CAS:Okadaic acid, free acidFormula:C44H68O13Purezza:>98%Colore e forma: white lyophilized solidPeso molecolare:805.00g/molOkadaic acid
CAS:Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.Formula:C44H68O13Purezza:98%Colore e forma:White Crystals Or PowderPeso molecolare:805Ref: TM-T16381
100μg (124.2μM*1mL in Ethanol)414,00€25μg (124.2μM*250μL in Ethanol)180,00€50μg (124.2μM*500μL in Ethanol)270,00€Okadaic Acid
CAS:Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);Formula:C44H68O13Colore e forma:NeatPeso molecolare:805.00Okadaic acid
CAS:Inhibitor of PP1 and PP2A protein phosphatasesFormula:C44H68O13Purezza:Min. 95%Peso molecolare:805 g/mol
