CAS 78214-33-2

Ginsenoside Rh2

Descrizione:

Ginsenoside Rh2 è un composto naturale classificato come una saponina triterpenoide, derivato principalmente dalle radici di Panax ginseng, una pianta nota per le sue proprietà medicinali. È caratterizzato dalla sua complessa struttura molecolare, che include uno scheletro simile a uno steroide con moieties di zucchero attaccate, contribuendo alla sua attività biologica. Ginsenoside Rh2 è riconosciuto per i suoi potenziali effetti farmacologici, comprese le proprietà antitumorali, antinfiammatorie e neuroprotettive. È stato studiato per la sua capacità di modulare varie vie di segnalazione, influenzando la proliferazione cellulare e l'apoptosi nelle cellule tumorali. Inoltre, Ginsenoside Rh2 mostra attività antiossidante, che può aiutare a ridurre lo stress ossidativo. Il composto si trova tipicamente in basse concentrazioni negli estratti di ginseng, richiedendo tecniche avanzate di estrazione e purificazione per applicazioni di ricerca e terapeutiche. Il suo profilo di sicurezza e efficacia sono oggetto di ricerche in corso, evidenziando la necessità di ulteriori studi per comprendere appieno i suoi meccanismi e potenziali benefici per la salute.

Formula: C₃₆H₆₂O₈

InChI: InChI=1S/C36H62O8/c1-20(2)10-9-14-36(8,42)21-11-16-35(7)27(21)22(38)18-25-33(5)15-13-26(32(3,4)24(33)12-17-34(25,35)6)44-31-30(41)29(40)28(39)23(19-37)43-31/h10,21-31,37-42H,9,11-19H2,1-8H3/t21-,22+,23+,24-,25+,26-,27-,28+,29-,30+,31-,33-,34+,35+,36-/m0/s1

InChI key: InChIKey=CKUVNOCSBYYHIS-IRFFNABBSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)CC4)[H])[H])[H]

Sinonimi:

• (3beta,12beta)-12,20-Dihydroxydammar-24-en-3-yl beta-D-glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• 20(S)-Ginsenoside Rh₂
• 20(S)-Rh2
• 3-O-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-20(S)-protopanaxadiol
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside 20-Rh2
• Ginsenoside Rh₂
• Ginsenoside rh2(S)
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
• Dammarane, β-D-glucopyranoside deriv.
• Ginsenoside Rh2
• β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl
• 3-O-β-D-Glucopyranosyl-20(S)-protopanaxadiol
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside
• β-D-Glucopyranoside, (3β,12β)-12,20-
• 12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside
• R-form-Ginsenoside Rh2
• dihydroxydammar-24-en-3-yl

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₆H₆₂O₈

Purezza: (HPLC) ≥98%

Colore e forma: Powder

Peso molecolare: 622.89

Ref: 11-0154S

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2

Purezza: ≥98%

Peso molecolare: 622.87g/mol

Ref: 54-BUP06318

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 is one of the most active components of red ginseng, controlling cancer and other metabolic diseases including osteoclast differentiation; ginsenoside Rh2 can suppress RANKL-induced osteoclast differentiation in vitro and in vivo through the regulation of c-Fos and NFATc1 expressions, not excluding the involvement of NF-κB and ERK, it is also suggested to be developed as a therapeutic drug for prevention and treatment of osteoporosis.

Formula: C₃₆H₆₂O₈

Purezza: 95%~99%

Colore e forma: White powder

Peso molecolare: 622.884

Ref: BP-BP0668

20(s)-Ginsenoside Rh2

CAS: 78214-33-2

Formula: C₃₆H₆₂O₈

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 622.87

Ref: 7W-GC1836

Ginsenoside Rh2

CAS: 78214-33-2

Formula: C₃₆H₆₂O₈

Peso molecolare: 622.88

Ref: 4Z-G-157005

Ginsenoside Rh2-d6

CAS: 78214-33-2

Formula: C₃₆H₅₆D₆O₈

Peso molecolare: 628.92

Ref: 4Z-G-157007

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.

Formula: C₃₆H₆₂O₈

Purezza: 99.20% - 99.76%

Colore e forma: White Powder

Peso molecolare: 622.87

Ref: TM-T2959

Ginsenoside rh2

CAS: 78214-33-2

Natural glycoside

Formula: C₃₆H₆₂O₈

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 622.89

Ref: 5G-89683

20(S)-Ginsenoside Rh2

Prodotto controllato

CAS: 78214-33-2

Applications 20(S)-Ginsenoside Rh2 is a bioactive metabolite of the ginsenoside component of Panax ginseng that has been shown to exhibit antibacterial effects in vitro.
References Zhang, J. et al.: Eur. J. Pharm., 740, 277 (2014);

Formula: C₃₆H₆₂O₈

Colore e forma: Neat

Peso molecolare: 622.87

Ref: TR-G387585

20(s)-Ginsenoside Rh2

CAS: 78214-33-2

20(s)-Ginsenoside Rh2 is a bioactive compound classified as a saponin, which is derived from the root of the Panax ginseng plant. This compound exhibits a wide range of pharmacological activities attributed to its ability to modulate cellular pathways. It exerts its mode of action primarily through the regulation of apoptosis, modulation of immune responses, and inhibition of tumor growth. Mechanistically, it interacts with cellular receptors and signaling molecules, influencing pathways such as NF-κB and MAPK, which are crucial in cell proliferation and apoptosis.

Formula: C₃₆H₆₂O₈

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 622.89 g/mol

Ref: 3D-OG09293

20(S)-Ginsenoside Rh2-d6

Prodotto controllato

CAS: 78214-33-2

Formula: C₃₆D₆H₅₆O₈

Colore e forma: Neat

Peso molecolare: 628.91

Ref: TR-G410290

Ginsenoside Rh2

CAS: 78214-33-2

Ginsenoside Rh2 is a bioactive compound, which is a triterpenoid saponin derived from the root of the Panax ginseng plant. It operates through multiple biochemical pathways, including the modulation of cell signaling cascades such as the inhibition of cell proliferation and the induction of apoptosis in cancer cells. These actions are primarily mediated through mitochondrial pathways and involve the regulation of pro-apoptotic and anti-apoptotic proteins.

Formula: C₃₆H₆₂O₈

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 622.87 g/mol

Ref: 3D-FG65764

(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside

CAS: 78214-33-2

Formula: C₃₆H₆₂O₈

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 622.8727

Ref: IN-DA00393A