CAS 78439-06-2

Ceftazidima pentaidrato

Descrizione:

Ceftazidima pentaidrato è un antibiotico cefalosporinico ad ampio spettro utilizzato principalmente nel trattamento di infezioni causate da batteri Gram-negativi. È caratterizzato dalla sua capacità di inibire la sintesi della parete cellulare batterica, rendendolo efficace contro una varietà di patogeni, inclusa Pseudomonas aeruginosa. La forma pentaidratata indica che il composto contiene cinque molecole d'acqua, il che può influenzare la sua solubilità e stabilità. Il ceftazidime è tipicamente somministrato per iniezione ed è spesso utilizzato in contesti ospedalieri per infezioni gravi, comprese quelle in pazienti immunocompromessi. La sua struttura chimica presenta un anello beta-lattamico, essenziale per la sua attività antibatterica. Il composto è generalmente ben tollerato, ma come tutti gli antibiotici, può causare effetti collaterali, comprese reazioni allergiche e disturbi gastrointestinali. A causa dell'emergere della resistenza agli antibiotici, il suo uso è spesso guidato da test di suscettibilità per garantire l'efficacia contro ceppi batterici specifici.

Formula: C₂₂H₂₂N₆O₇S₂·5H₂O

InChI: InChI=1S/C22H22N6O7S2.5H2O/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27;;;;;/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34);5*1H2/b26-13-;;;;;/t14-,18-;;;;;/m1...../s1

InChI key: InChIKey=NMVPEQXCMGEDNH-TZVUEUGBSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(O)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]=4C=CC=CC4)[H].O

Sinonimi:

• (6R,7R)-7-({(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-({(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
• Cefidime
• Ceftadizim
• Glazidim
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, hydrate (1:5)
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, pentahydrate
• Pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, pentahydrate, [6R-[6α,7β(Z)]]-
• Starcef 1
• pentahydrate (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxyiminoacetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftazidime pentahydrate

Ceftazidime pentahydrate, 95%

CAS: 78439-06-2

Ceftazidime pentahydrate is an antibacterial agent. It is used especially for Pseudomonas and other gram-negative infections in debilitated patients. It is used in the treatment of patients with infections caused by susceptible strains of organisms in the following diseases: lower respiratory tract

Formula: C₂₂H₃₂N₆O₁₂S₂

Purezza: 95%

Colore e forma: Powder or crystals or crystalline powder, White to off-white

Peso molecolare: 636.65

Ref: 02-J66460

CEFTAZIDIME CRS

CAS: 78439-06-2

CEFTAZIDIME CRS

Ref: 41-C0690500

Ceftazidime Pentahydrate

CAS: 78439-06-2

Antibiotics nesoi

Formula: C₂₂H₂₂N₆O₇S₂·5H₂O

Colore e forma: White Cream Crystalline Powder

Peso molecolare: 636.15196

Ref: 45-1098130

Ceftazidime pentahydrate

CAS: 78439-06-2

Formula: C₂₂H₃₂N₆O₁₂S₂

Purezza: %

Colore e forma: Solid

Peso molecolare: 636.6525

Ref: IN-DA005B3Q

Ceftazidime hydrate, contains approx. 10% sodium carbonate

CAS: 78439-06-2

Formula: C₂₂H₂₂N₆O₇S₂·xH₂O

Purezza: 95.0 - 102.0 % (on dried basis)

Colore e forma: White to off-white crystalline powder

Peso molecolare: 546.58

Ref: 7W-GA1898

Ceftazidime Pentahydrate

CAS: 78439-06-2

Ceftazidime Pentahydrate

Purezza: ≥98%

Peso molecolare: 636.65g/mol

Ref: 54-BUP18349

Ceftazidime hydrate

CAS: 78439-06-2

Formula: C₂₂H₂₂N₆O₇S₂·xH₂O

Purezza: 95.0 - 102.0 % (anhydrous basis)

Colore e forma: White to off-white crystalline powder

Peso molecolare: 546.58 (anhydrous)

Ref: 7W-GA6002

Ceftazidime Pentahydrate

CAS: 78439-06-2

Ceftazidime Pentahydrate

Purezza: 95%

Peso molecolare: 636.65g/mol

Ref: 54-OR1024612

Ceftazidime hydrate, USP grade

CAS: 78439-06-2

Formula: C₂₂H₂₂N₆O₇S₂·xH₂O

Purezza: (HPLC) 95.0 - 102.0 % (dried basis)

Colore e forma: White to off-white powder or crystals

Peso molecolare: 546.58 (anhydrous)

Ref: 7W-GP7286

Ceftazidime RS

CAS: 78439-06-2

Colore e forma: White To Light Yellow-White Solid Crystalline Powder

Ref: 2K-7000560021

Ceftazidime Pentahydrate

CAS: 78439-06-2

Ceftazidime Pentahydrate is a cephalosporin antibiotic with activity against gram-negative bacilli and may be used to study infectious diseases.

Formula: C₂₂H₃₂N₆O₁₂S₂

Purezza: 99.39%

Colore e forma: White To Cream-Colored Crystalline Powder

Peso molecolare: 636.65

Ref: TM-T8261

Ceftazidime Pentahydrate(Contain 1 equivalent of Na2CO3 as stabilizer)

CAS: 78439-06-2

Applications Third generation cephalosporin antibiotic. Antibacterial.
References Brodie, A., et al.: Antimicrob. Agents Chemother., 17, 876 (1980), Richards, D.M., et al.: Drugs, 29, 105 (1985), Abounassif, M.A., et al.: Anal. Profiles Drug Subs., 19, 95 (1990),

Formula: C₂₂H₂₂N₆O₇S₂·5H₂O

Colore e forma: White

Peso molecolare: 636.65

Ref: TR-C244100

Ceftazidime-d5 (>90%)

Prodotto controllato

CAS: 78439-06-2

Stability Light, Moisture and temperature sensitive
Applications Third generation cephalosporin antibiotic. Antibacterial.
References Brodie, A., et al.: Antimicrob. Agents Chemother., 17, 876 (1980), Richards, D.M., et al.: Drugs, 29, 105 (1985), Abounassif, M.A., et al.: Anal. Profiles Drug Subs., 19, 95 (1990),

Formula: C₂₂H₁₇D₅N₆O₇S₂

Purezza: 90%

Colore e forma: Neat

Peso molecolare: 551.61

Ref: TR-C244102

Ceftazidime impurity B

CAS: 78439-06-2

Ceftazidime impurity B is a ceftazidime impurity that is found in the drug Ceftazidime. Ceftazidime is an antibiotic that belongs to the group of cephalosporin antibiotics and inhibits bacterial growth by inhibiting cell wall synthesis. Ceftazidime impurity B has been shown to be toxic to gram-positive bacteria, such as Enterococcus faecium and Staphylococcus aureus, but not to gram-negative bacteria, such as Escherichia coli. In addition, it has been shown to have no effect on the IL-2 receptor of T cells or the binding of penicillin-binding protein. It has also been shown to be safe for injection into mice and rats in toxicity studies.

Formula: C₂₂H₂₂N₆O₇S₂

Purezza: Min. 95%

Peso molecolare: 546.58 g/mol

Ref: 3D-IC63717

Ceftazidime pentahydrate

CAS: 78439-06-2

A broad-spectrum antibiotic of cephalosporin class, which inhibits bacterial cell wall synthesis by targeting the penicillin-binding protein, involved in peptidoglycan synthesis. This third-generation cephalosporin is very active against Pseudomonas species and can also be used to treat bacterial meningitis as it penetrates in the cerebrospinal fluid.

Formula: C₂₂H₃₂N₆O₁₂S₂

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 636.65 g/mol

Ref: 3D-AC19871