CAS 78628-80-5

Cloridrato di terbinafina

Descrizione:

Cloridrato di terbinafina è un farmaco antifungino utilizzato principalmente per trattare infezioni da dermatofiti, come il piede d'atleta, la tigna e il fungo delle unghie. Appartiene alla classe degli antifungini chiamati alilamine e agisce inibendo l'enzima squalene epossidasi, che è cruciale per la sintesi dell'ergosterolo, un componente essenziale delle membrane cellulari fungine. Questa interruzione porta alla morte cellulare ed elimina efficacemente l'infezione. Cloridrato di terbinafina viene tipicamente somministrato per via orale o topica, a seconda del tipo e della gravità dell'infezione. La sostanza è caratterizzata dalla sua forma di polvere cristallina bianca a bianco sporco, con una solubilità relativamente bassa in acqua, che può influenzare la sua assorbimento e biodisponibilità. Ha una formula molecolare che riflette la sua struttura complessa e la sua farmacocinetica comporta un ampio metabolismo epatico. Gli effetti collaterali possono includere disturbi gastrointestinali, reazioni cutanee e, in rari casi, tossicità epatica. In generale, Cloridrato di terbinafina è un agente potente e ampiamente utilizzato nel trattamento delle infezioni fungine, con un profilo di sicurezza ben stabilito quando usato come indicato.

Formula: C₂₁H₂₆ClN

InChI: InChI=1/C21H25N/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19/h5-7,9-14H,16-17H2,1-4H3/b9-5+

InChI key: InChIKey=BWMISRWJRUSYEX-SZKNIZGXSA-N

SMILES: C(N(C/C=C/C#CC(C)(C)C)C)C=1C2=C(C=CC1)C=CC=C2.Cl

Sinonimi:

• (2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine
• (E)-N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethylaminehydroc
• (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride
• (E)-N-(6,6-dimethyl-2-heptene-4-alkyne)-N-methyl-l-naphthalene methylamine hydrochloride
• 1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, hydrochloride, (E)-
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1)
• 1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-ynyl]-N-methyl-, hydrochloride
• Bramazil
• Bramizil
• Lamisil
• Lamisil Once
• Lamosil
• Muzonal
• N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethanamin(E)-1-
• N-(6,6-Dimethyl-2-Hepten-4-Ynyl)-N-Methyl-1-Naphthalenemethanamin(E)-1-Naphthalenemethanaminmon
• Naphthalenemethanaminmonohydrochloride
• Terbina
• Terbinafine HCl
• Terbinafine・HCL
• Terbine
• Terbutaline hydrochloride
• Terbinafine hydrochloride
• Terbinafine Hydrochloride
• TERNBINAFINEHCL
• N-[(2E)-6,6-DIMETHYL-2-HEPTEN-4-YNYL]-N-METHYL-1-NAPHTHALENEMETHANAMINE
• TRANS-N-(6,6-DIMETHYL-2-HEPTEN-4-YNYL)-N-METHYL-1-NAPHTHYLMETHYLAMINE HYDROCHLORIDE
• Terbinafine hdyrochloride
• Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine
• Trebinafine hydrochloride
• TerbutalineSulfateBase

Terbinafine

CAS: 78628-80-5, 91161-71-6

Formula: C₂₁H₂₅N

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 291.44

Ref: 3B-T3677

Terbinafine Hydrochloride

CAS: 78628-80-5, 91161-71-6

Formula: C₂₁H₂₅N·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 327.90

Ref: 3B-D2049

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride

Formula: C₂₁H₂₅N / C₂₁H₂₆CIN

Purezza: 88.6% / 99.7%

Colore e forma: White. To. Off-White

Peso molecolare: 291.1987 / 431.111

Ref: 47-1159

TERBINAFINE FOR SYSTEM SUITABILITY CRS

CAS: 78628-80-5

TERBINAFINE FOR SYSTEM SUITABILITY CRS

Formula: C₂₁H₂₆ClN

Peso molecolare: 327.8908

Ref: 41-Y0001143

TERBINAFINE HYDROCHLORIDE CRS

CAS: 78628-80-5

TERBINAFINE HYDROCHLORIDE CRS

Formula: C₂₁H₂₆ClN

Colore e forma: White. Powder.

Peso molecolare: 327.8908

Ref: 41-Y0000535

Terbinafine Hydrochloride

CAS: 78628-80-5

Aromatic monoamines and their derivatives, salts thereof, nesoi

Formula: C₂₁H₂₅N·HCl

Colore e forma: White Powder

Peso molecolare: 291.1987

Ref: 45-1643496

[(2E)-6,6-dimethylhept-2-en-4-yn-1-yl](methyl)(naphthalen-1-ylmethyl)amine hydrochloride

CAS: 78628-80-5

Formula: C₂₁H₂₆ClN

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 327.8908

Ref: IN-DA003UI5

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.

Formula: C₂₁H₂₆ClN

Purezza: 99.16% - 99.95%

Colore e forma: Crystalline Powder

Peso molecolare: 327.89

Ref: TM-T1411

({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride

CAS: 78628-80-5

({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride

Purezza: 98%

Peso molecolare: 327.89g/mol

Ref: 54-OR13685

Terbinafine hydrochloride

CAS: 78628-80-5

Formula: C₂₁H₂₅N·HCl

Purezza: 99.0 - 101.0 % (dried basis)

Colore e forma: White powder

Peso molecolare: 327.89

Ref: 7W-GA7211

Terbinafine hydrochloride

CAS: 78628-80-5

Terbinafine hydrochloride

Purezza: ≥98%

Peso molecolare: 327.89g/mol

Ref: 54-BUP16916

Terbinafine-d7 HCl

CAS: 78628-80-5

Formula: C₂₁H₁₈D₇N·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 298.48 36.46

Ref: 4Z-T-542

Terbinafine hydrochloride, EP grade

CAS: 78628-80-5

Formula: C₂₁H₂₅N·HCl

Purezza: ≤ 0.1%

Colore e forma: White or almost white powder

Peso molecolare: 327.89

Ref: 7W-GA9882

Terbinafine Hydrochloride

CAS: 78628-80-5

Colore e forma: Neat

Ref: 86-MM0696.00

Terbinafine hydrochloride

CAS: 78628-80-5

Formula: C₂₁H₂₅N·ClH

Colore e forma: Neat

Peso molecolare: 327.89

Ref: 04-C17255000

Terbinafine Hydrochloride

CAS: 78628-80-5

Applications An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Petranyi, G., et al.: Science, 224, 1239 (1984), Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985), Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999),

Formula: C₂₁H₂₅N·ClH

Colore e forma: Neat

Peso molecolare: 327.89

Ref: TR-T107500

Terbinafine hydrochloride

CAS: 78628-80-5

Activator of the two-pore domain potassium channel TASK3

Formula: C₂₁H₂₆ClN

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 327.89 g/mol

Ref: 3D-FT28039

Terbinafine HCl - Bio-X ™

CAS: 78628-80-5

Terbinafine is an antifungal drug that is used in the treatment of dermatophyte infections of the toenails and fingernails. Terbinafine also treats other skin infections. This drug works by inhibiting ergosterol synthesis which in return inhibits fungal squalene monooxygenase. This results in a disruption of fungal cell wall synthesis.

Formula: C₂₁H₂₅N•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 327.89 g/mol

Ref: 3D-BT164461

Terbinafine hydrochloride

CAS: 78628-80-5

Formula: C₂₁H₂₆ClN

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 327.9

Ref: 10-F332489

Terbinafine Hydrochloride

CAS: 78628-80-5

Formula: C₂₁H₂₅NHCl

Peso molecolare: 291.4 : 36.46

Ref: ST-EA-CP-T34010