CAS 78858-44-3

(2R)-3-(esadecilossi)-2-metossipropil 2-(trimetilammonio)etil fosfato

Descrizione:

La sostanza chimica nota come (2R)-3-(esadecilossi)-2-metossipropil 2-(trimetilammonio)etil fosfato, con il numero CAS 78858-44-3, è un composto di ammonio quaternario che presenta proprietà anfifiliche grazie alle sue caratteristiche idrofili e idrofobiche duali. Questo composto presenta un gruppo esadecilico a catena lunga, che contribuisce alla sua lipofilia, mentre il gruppo trimetilammonio fornisce una carica positiva, migliorando la sua solubilità in solventi polari. La presenza del gruppo fosfato aumenta ulteriormente la sua idrofilia, rendendolo adatto per varie applicazioni nei campi biochimici e farmaceutici, in particolare nei sistemi di rilascio di farmaci e come tensioattivo. La sua configurazione strutturale gli consente di interagire con le membrane biologiche, facilitando potenzialmente il trasporto di molecole attraverso le membrane lipidiche. Inoltre, questo composto può presentare proprietà antimicrobiche, rendendolo di interesse nello sviluppo di agenti antimicrobici. In generale, le sue caratteristiche strutturali uniche consentono una gamma di funzionalità sia nella ricerca che nelle applicazioni industriali.

Formula: C₂₅H₅₄NO₆P

InChI: InChI=1/C25H54NO6P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-30-23-25(29-5)24-32-33(27,28)31-22-20-26(2,3)4/h25H,6-24H2,1-5H3/t25-/m1/s1

SMILES: CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC

Sinonimi:

• ethanaminium, 2-[[[[(2R)-3-(hexadecyloxy)-2-methoxypropyl]oxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine is a useful scaffold, versatile building block, and useful intermediate that can be used in the synthesis of complex compounds. It is a high quality reagent and research chemical that can be used as a reaction component for speciality chemicals. 1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine has CAS number 788584443.

Formula: C₂₅H₅₄NO₆P

Purezza: Min. 95 Area-%

Peso molecolare: 495.67 g/mol

Ref: 3D-H-1844

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine

CAS: 78858-44-3

1-O-Hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine (HPC) is a phospholipid that is synthesized from the essential fatty acid linoleic acid. It has been shown to have an inhibitory effect on leukemia cells, which may be due to its ability to induce apoptosis by inducing the death of tumor cells and inhibiting protein synthesis. HPC also interacts synergistically with other agents such as phorbol esters, which can lead to increased cell death. This drug has been shown to have immunomodulatory effects in fibrosarcoma cells, where it inhibits tumor growth and induces apoptotic cell death. HPC binds to specific antigens and modulates immune responses through the inhibition of diacylglycerol production.

Formula: C₂₅H₅₄NO₆P

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 495.68 g/mol

Ref: 3D-FH177698

2-O-methyl PAF C-16

CAS: 78858-44-3

2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).

Formula: C₂₅H₅₄NO₆P

Colore e forma: Solid

Peso molecolare: 495.7

Ref: TM-T84610