CAS 79517-01-4

Octreotide

Descrizione:

Octreotide è un analogo sintetico di octapeptide della somatostatina, un ormone che si verifica naturalmente e inibisce la secrezione di diversi altri ormoni e sostanze nel corpo. È utilizzato principalmente nel campo medico per la sua capacità di ridurre i livelli di ormone della crescita e gestire condizioni come l'acromegalia, alcuni tipi di tumori e diarrea severa associata a tumori neuroendocrini. Octreotide mostra un'alta affinità per i recettori della somatostatina, in particolare il sottotipo 2, che contribuisce ai suoi effetti terapeutici. Il composto è tipicamente somministrato per via sottocutanea o endovenosa e ha una vita media più lunga rispetto alla somatostatina naturale, consentendo una somministrazione meno frequente. In termini di proprietà fisiche, Octreotide è una polvere bianca o bianco sporco che è solubile in acqua e mostra stabilità in condizioni di stoccaggio appropriate. La sua struttura molecolare include un legame disolfuro ciclico, che ne aumenta la resistenza alla degradazione enzimatica, rendendolo efficace per l'uso clinico. In generale, Octreotide rappresenta un significativo progresso nella gestione dei disturbi legati agli ormoni.

Formula: C₄₉H₆₆N₁₀O₁₀S₂

InChI: InChI=1/C49H66N10O10S2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64)/t28-,29?,34-,36+,37+,38-,39-,40+,41+,42+/m1/s1

Sinonimi:

• Ccris 8708
• D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide acetate (salt)
• D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2-7)-disulfide acetate (salt)
• L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2-7)-disulfide, (R-(R*,R*))-, acetate (salt)
• (Preservative Free)
• Sms 201-995
• Sandostatin
• Sandostatin LAR
• Sandostatin LAR Depot
• Unii-75R0U2568I
• (4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-19-(D-phenylalanylamino)-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carboxamide acetate (1:1)

Octreotide

CAS: 79517-01-4

Octreotide is a longer acting synthetic octapeptide analog of the naturally occurring hormone somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormones. Melacini et al. studied the conformation of the peptide in solution by NMR. CAS Number (net): 83150-76-9.

Formula: C₄₉H₆₆N₁₀O₁₀S₂

Purezza: ≥ 99.5%

Colore e forma: White

Peso molecolare: 1019.26

Ref: 01-4042822

OCTREOTIDE CRS

CAS: 79517-01-4

OCTREOTIDE CRS

Ref: 41-Y0002104

OCTREOTIDE FOR NMR IDENTIFICATION CRS

CAS: 79517-01-4

OCTREOTIDE FOR NMR IDENTIFICATION CRS

Ref: 41-Y0002105

Octreotide Acetate

CAS: 79517-01-4

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Formula: C₄₉H₆₆N₁₀O₁₀S₂·xC₂H₄O₂

Colore e forma: White Powder

Peso molecolare: 1018.44048

Ref: 45-1477604

Octreotide Acetate

CAS: 79517-01-4

Formula: C₅₁H₇₀N₁₀O₁₂S₂

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 1079.2913

Ref: IN-DA019FSF

Octreotide Acetate

CAS: 79517-01-4

Octreotide Acetate

Purezza: ≥98%

Peso molecolare: 1079.3g/mol

Ref: 54-BUP10206

Octreotide acetate

CAS: 79517-01-4

Formula: C₄₉H₆₆N₁₀O₁₀S₂·x(CH₃COOH)

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 1019.24 (free acid)

Ref: 7W-GP4360

Octreotide Acetate

CAS: 79517-01-4

Formula: C₄₉H₆₆N₁₀O₁₀S₂

Purezza: 95%~99%

Colore e forma: White to Off-white Powder

Peso molecolare: 1019.24

Ref: BP-BPPG052

Octreotide Acetate

CAS: 79517-01-4

Formula: C₄₉H₆₆N₁₀O₁₀S₂·2C₂H₄O₂

Peso molecolare: 1019.25 2 60.05

Ref: 4Z-PO-036002

Octreotide Acetate

CAS: 79517-01-4

Octreotide Acetate (Sandostatin) is a potent, long-acting synthetic somatostatin octapeptide analog that inhibits secretion of growth hormone.

Formula: C₅₁H₇₀N₁₀O₁₂S₂

Purezza: 99.03% - 99.87%

Colore e forma: Less To Off-White Lyophilised Solid Colourless To Off-White Lyophilised Solid

Peso molecolare: 1079.3

Ref: TM-T4119

Octreotide Acetate

CAS: 79517-01-4

Applications Octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly.
References Bauer, W., et al.: Life Sci., 31, 1133 (1982), Plewe, G., et al.: Lancet, 2, 782 (1984), Kraenzlin, M.E., et al.: Experientia, 41, 738 (1985), del Pozo, E., et al.: Acta Endocrinol., 111, 433 (1986),

Formula: C₄₉H₆₆N₁₀O₁₀S₂·C₂H₄O₂

Colore e forma: White To Off-White

Peso molecolare: 1079.29

Ref: TR-O239950

Octreotide acetate

CAS: 79517-01-4

Octapeptide analog of Somatostatin; inhibits insulin and growth hormones

Formula: C₄₉H₆₆N₁₀O₁₀S₂·xCH₃COOH

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 1,019.24 g/mol

Ref: 3D-FO26520

Octreotide Acetate

CAS: 79517-01-4

Purezza: 99%

Peso molecolare: 1079.300049

Ref: 10-F864034