CAS 79907-44-1

Procianidina B2 3,3′-di-O-gallato

Descrizione:

Procianidina B2 3,3′-di-O-gallato è un composto polifenolico appartenente alla famiglia dei flavonoidi, specificamente un tipo di proantocianidina. È caratterizzato dalla sua struttura complessa, che include più anelli fenolici e gruppi galoyl, contribuendo alle sue proprietà antiossidanti. Questo composto è noto per la sua presenza in varie fonti vegetali, in particolare in frutta, semi e alcuni tipi di tè. Procianidina B2 3,3′-di-O-gallato mostra significative attività biologiche, inclusi effetti anti-infiammatori, anti-cancro e cardioprotettivi, rendendolo di interesse nella ricerca nutrizionale e farmaceutica. La sua solubilità può variare a seconda del solvente, ed è generalmente più solubile nei solventi organici che in acqua. La stabilità del composto può essere influenzata da fattori come pH e temperatura, che sono considerazioni importanti sia nella scienza alimentare che nella farmacologia. In generale, Procianidina B2 3,3′-di-O-gallato è un composto prezioso per i suoi potenziali benefici per la salute e il suo ruolo nello studio degli antiossidanti naturali.

Formula: C₄₄H₃₄O₂₀

InChI: InChI=1/C44H34O20/c45-19-11-26(51)34-32(12-19)61-40(16-2-4-22(47)25(50)6-16)42(64-44(60)18-9-30(55)38(58)31(56)10-18)36(34)35-27(52)14-23(48)20-13-33(62-43(59)17-7-28(53)37(57)29(54)8-17)39(63-41(20)35)15-1-3-21(46)24(49)5-15/h1-12,14,33,36,39-40,42,45-58H,13H2/t33-,36-,39-,40-,42-/m1/s1

InChI key: InChIKey=KTLUHRSHFRODPS-RIQPQZJCSA-N

SMILES: O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@H](C=3C(O[C@@H]2C4=CC(O)=C(O)C=C4)=CC(O)=CC3O)C5=C6C(C[C@@H](OC(=O)C7=CC(O)=C(O)C(O)=C7)[C@H](O6)C8=CC(O)=C(O)C=C8)=C(O)C=C5O

Sinonimi:

• (-)-Epicatechin-3-O-galloyl-(4β,8)-(-)-epicatechin-3-O-gallate
• (2R,3R)-3-O-Galloylepicatechin-4β,8-[(2R,3R)-3-O-galloylepicatechin]
• 3,3′-Digalloylprocyanidin B2
• Benzoic acid, 3,4,5-trihydroxy-, (2R,2′R,3R,3′R,4R)-2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-5,5′,7,7′-tetrahydroxy[4,8′-bi-2H-1-benzopyran]-3,3′-diyl ester
• Benzoic acid, 3,4,5-trihydroxy-, 2,2′-bis(3,4-dihydroxyphenyl)-3,3′,4,4′-tetrahydro-5,5′,7,7′-tetrahydroxy[4,8′-bi-2H-1-benzopyran]-3,3′-diyl ester, [2R-[2α,3α,4β(2′R*,3′R*)]]-
• Proanthocyanidin B2 3,3′-O-gallate
• Procyanidin B₂ 3,3′-di-O-gallate
• [3-O-Galloyl]-(-)-epicatechin-(4β,8)-(+)-epicatechin-3-O-gallate
• benzoic acid, 3,4,5-trihydroxy-, (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-5,5',7,7'-tetrahydroxy[4,8'-bi-2H-1-benzopyran]-3,3'-diyl ester
• Procyanidin B2 3,3′-di-O-gallate
• Benzoic acid, 3,4,5-trihydroxy-, 2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-5,5',7,7'-tetrahydroxy[4,8'-bi-2H-1-benzopyran]-3,3'-diyl ester, [2R-[2.alpha.,3.alpha.,4.beta.(2'R*,3'R*)]]-
• Aids-082250
• (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-5,5',7,7'-tetrahydroxy-[4,8'-bichroman]-3,3'-diyl bis(3,4,5-trihydroxybenzoate)
• (2R,3R)-3-o-Galloylepicatechin-4.beta.,8-[(2R,3R)-3-o-galloylepicatechin]
• Aids082250
• [(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-4-[(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-chroman-8-yl]-5,7-dihydroxy-chroman-3-yl] 3,4,5-trihydroxybenzoate
• Procyanidin B2 3,3'-di-O-gallate (&gt

2-[(2r,3r,4s,5r,6s)-6-[(1s)-1-[(2s,5r,7s,8r,9s)-2-[(5s)-5-[(2r,3s,4r,5r)-5-[(3s,4s,5r,6s)-6-hydroxy-4-methoxy-3,5,6-trimethyl-tetrahydropyran-2-yl]-4-methoxy-3-methyl-tetrahydrofuran-2-yl]-5-methyl-tetrahydrofuran-2-yl]-9-methoxy-2,8-dimethyl-1,6-dioxaspi

CAS: 79907-44-1

Formula: C₄₄H₃₄O₂₀

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 882.7288

Ref: IN-DA0054WP

Procyanidin B2 3,3'-di-O-gallate (>80%)

Prodotto controllato

CAS: 79907-44-1

Applications Procyanidin B2 3,3'-di-O-gallate is an important compound whose activity results in the inhibition of growth pertaining to human prostate carcinoma cell lines. Coming from the group of compounds known as flavonoids, Procyanidin B2 3,3'-di-O-gallate shows interesting biological activities relating to various human cancer diseases.
References Saito, A. et al.: Heterocycles, 80, 1081 (2010); Shrestha, S.P. et al.: Pharm. Res., 29, 856 (2012);

Formula: C₄₄H₃₄O₂₀

Purezza: >80%

Colore e forma: Neat

Peso molecolare: 882.73

Ref: TR-P755825

Procyanidin B2 3,3'-di-o-gallate

CAS: 79907-44-1

Procyanidin B2 3,3'-di-o-gallate (PB2DOG) is a gallotannin that can be found in the leaves of the dogwood tree. It has dose-dependent effects on the serine protease activity of butanol, which is used as a model for pancreatic lipase. PB2DOG also inhibits the activity of viruses such as hepatitis C and herpes simplex virus type 1, and cancer cells such as du145 and japonica. PB2DOG has been shown to induce apoptosis in cancer cells by reducing DNA synthesis and inhibiting protein synthesis. The mechanism behind this effect is not fully understood, but it may be related to its ability to inhibit cCAAT/enhancer binding protein (C/EBP), an important transcription factor for cell proliferation.

Formula: C₄₄H₃₄O₂₀

Purezza: Min. 95%

Peso molecolare: 882.7 g/mol

Ref: 3D-EDA90744