CAS 80-49-9

Metobromuro di omatropina

Descrizione:

Metobromuro di omatropina è un agente anticolinergico sintetico utilizzato principalmente in oftalmologia per indurre midriasi (dilatazione della pupilla) e cicloplegia (paralisi del muscolo ciliare). È un composto di ammonio quaternario, il che significa che porta una carica positiva, migliorando la sua solubilità in acqua e limitando la sua capacità di attraversare la barriera ematoencefalica. Questa caratteristica riduce gli effetti collaterali sul sistema nervoso centrale rispetto ad altri anticolinergici. La sostanza viene tipicamente somministrata come collirio ed è nota per il suo inizio d'azione relativamente rapido e la durata moderata dell'effetto. Oltre alle sue applicazioni oftalmiche, può essere utilizzata anche in altri contesti medici in cui sono desiderati effetti anticolinergici. Gli effetti collaterali comuni possono includere secchezza delle fauci, visione offuscata e aumento della pressione intraoculare. Grazie al suo profilo farmacologico specifico, Metobromuro di omatropina è uno strumento prezioso sia in contesti diagnostici che terapeutici nella cura degli occhi.

Formula: C₁₇H₂₄BrNO₃

InChI: InChI=1/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3/t12-,13+,14+,15?

InChI key: InChIKey=FUFVKLQESJNNAN-RIMUKSHENA-M

SMILES: C[N+]1(C)[C@]2(C[C@H](OC(C(O)C3=CC=CC=C3)=O)C[C@@]1(CC2)[H])[H].[Br-]

Sinonimi:

• 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
• 1αH,5αH-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate
• 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-
• 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, endo-
• 8-Methylhomatropinium bromide
• Arkitropin
• Camatropine
• Esopin
• Helbatropin
• Homapin
• Homatrocel
• Homatromide
• Homatropil
• Homatropine Methylbromide
• Homatropine methobromide
• Homatropinmethylbromid
• Homolone
• Malcotran
• Mesopin
• Methatropin
• Methatropine
• Methylbromure d'homatropine
• Methylhomatropine bromide
• Methylhomatropine hydrobromide
• Methylhomatropinium bromide
• Metilbromuro De Homatropina
• Novatrin
• Novatrine
• Novatropin
• Novatropine
• Nsc 34399
• Sed-Tems
• Sethyl
• Tropinium methobromide mandelate
• 3-{[hydroxy(phenyl)acetyl]oxy}-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
• N-methylhomatropinium bromide
• dl-homatropine methyl bromide
• 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, (3-endo)-
• (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate - bromomethane (1:1)
• (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate
• Homatropine methyl bromide
• dl-methylbromide
• methylhomatropine
• 3-alpha-hydroxy-8-methyl-1-alpha-h,5-alpha-h-tropaniumbromidemandelate
• 3-((hydroxyphenylacetyl)oxy)-8,8-dimethyl-8-azoniabicyclo(3.2.1)octanbro
• endo-mid
• 8-methyl-homatropiniubromide

Homatropine Methyl Bromide

CAS: 80-49-9

Formula: C₁₇H₂₄BrNO₃

Purezza: >99.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 370.29

Ref: 3B-H0448

HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS

CAS: 80-49-9

HOMATROPINE METHYLBROMIDE FOR SYSTEM SUITABILITY CRS

Formula: C₁₆H₂₁NO₃

Colore e forma: Powder

Peso molecolare: 275.3428

Ref: 41-Y0001383

HOMATROPINE METHYLBROMIDE CRS

CAS: 80-49-9

HOMATROPINE METHYLBROMIDE CRS

Formula: C₁₆H₂₁NO₃

Colore e forma: Powder

Peso molecolare: 275.3428

Ref: 41-H0830000

Homatropine Methylbromide

CAS: 80-49-9

Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi

Formula: C₁₇H₂₄BrNO₃

Colore e forma: White Colorless Powder

Peso molecolare: 370.28

Ref: 45-1311000

Methylhomatropine (bromide)

CAS: 80-49-9

Formula: C₁₇H₂₄BrNO₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 370.2814

Ref: IN-DA0052J6

Homatropine Methylbromide

CAS: 80-49-9

Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.

Formula: C₁₇H₂₄BrNO₃

Purezza: 98.97%

Colore e forma: Solid

Peso molecolare: 370.29

Ref: TM-T0427

Homatropine Methylbromide

CAS: 80-49-9

Homatropine Methylbromide

Purezza: ≥98%

Peso molecolare: 370.29g/mol

Ref: 54-BUP14155

Homatropine Methylbromide

Prodotto controllato

CAS: 80-49-9

Formula: C₁₇H₂₄NO₃·Br

Colore e forma: Neat

Peso molecolare: 370.28

Ref: 86-MM0792.00

Homatropine methylbromide

Prodotto controllato

CAS: 80-49-9

Formula: C₁₇H₂₄NO₃·Br

Colore e forma: Neat

Peso molecolare: 370.28

Ref: 04-C14213400

Homatropine methyl bromide

CAS: 80-49-9

Homatropine methyl bromide is a drug that belongs to the class of anticholinergic drugs. It is used as a pharmaceutical preparation and is used in the treatment of glaucoma, diagnosis of myasthenia gravis, and as an antidote for organophosphate poisoning. Homatropine methyl bromide can be used to control diastolic pressure. This drug binds to acetylcholine receptors and increases the time needed for hydrochloric acid to break down propranolol hydrochloride. The binding constants for this drug are high, which means it has a strong affinity for acetylcholine receptors. Homatropine methyl bromide is chemically stable and does not react with fatty acids or other chemicals.

Formula: C₁₇H₂₄NO₃•Br

Purezza: Min. 95%

Peso molecolare: 370.28 g/mol

Ref: 3D-FH33973

Homatropine Methylbromide

Prodotto controllato

CAS: 80-49-9

Applications Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.
References Schroeder, F., et al.: Biochemistry, 34, 11919 (1995); Krungkrai, J., et al.: Bioorg. Med. Chem., 15, 483 (2005); Zeng, B., et al.: Microbiology, 152, 2355 (2006); Hongmanee, P., et al.: Antimicrob. Agents Chemother., 51, 1105 (2007);

Formula: C₁₇H₂₄NO₃·Br

Colore e forma: White To Off-White

Peso molecolare: 370.28

Ref: TR-H459225

Homatropine Methylbromide

CAS: 80-49-9

Formula: C₁₇H₂₄NO₃Br

Peso molecolare: 290.4 : 79.9

Ref: ST-EA-CP-H5005

Homatropine Methylbromide

CAS: 80-49-9

Colore e forma: Neat

Ref: 61-FOR0792.00