CAS 804-30-8

Fursultiamina

Descrizione:

Fursultiamina, noto anche come disolfuro di propile di tiamina, è un derivato sintetico della tiamina (vitamina B1) che viene utilizzato principalmente come integratore alimentare e nel trattamento della carenza di tiamina. È caratterizzato dalla sua capacità di migliorare la biodisponibilità della tiamina, rendendola più efficace nel corpo. Fursultiamina è solubile nei lipidi, il che consente una migliore assorbimento rispetto alla tiamina solubile in acqua. Il composto è spesso utilizzato in formulazioni destinate a migliorare la funzione neurologica e il metabolismo energetico, poiché la tiamina svolge un ruolo cruciale nel metabolismo dei carboidrati e nella funzione nervosa. La sua struttura chimica include un legame disolfuro, che contribuisce alle sue proprietà ed efficacia uniche. Fursultiamina è generalmente considerato sicuro se usato come indicato, ma come qualsiasi integratore, può avere effetti collaterali potenziali o interazioni con altri farmaci. Come con qualsiasi agente terapeutico, è importante consultare professionisti sanitari prima dell'uso, specialmente in individui con condizioni di salute sottostanti o quelli che assumono altri farmaci.

Formula: C₁₇H₂₆N₄O₃S₂

InChI: InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)

InChI key: InChIKey=JTLXCMOFVBXEKD-UHFFFAOYSA-N

SMILES: C(N(C(=C(SSCC1CCCO1)CCO)C)C=O)C=2C(N)=NC(C)=NC2

Sinonimi:

• Adventan
• Alinamin F
• Diteftin
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-
• Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-
• Fursultiamin
• Fursultiamine
• Judolor
• Linamin
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide
• N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]formamide
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{(1Z)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide
• N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{5-hydroxy-3-[(tetrahydrofuran-2-ylmethyl)disulfanyl]pent-2-en-2-yl}formamide
• Retar B₁
• Tetrahydrofurfuryl thiamine disulfide
• Thiamin tetrahydrofurfuryl disulfide

Formamide,N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-

CAS: 804-30-8

Formula: C₁₇H₂₆N₄O₃S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 398.5433

Ref: IN-DA01CBCQ

Fursultiamine, 10mM (in DMSO)

CAS: 804-30-8

Fursultiamine, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 398.54g/mol

Ref: 54-BUP19966

Fursultiamine

CAS: 804-30-8

Fursultiamine

Purezza: ≥98%

Peso molecolare: 398.54g/mol

Ref: 54-BUP06909

Fursultiamine

CAS: 804-30-8

Formula: C₁₇H₂₆N₄O₃S₂

Purezza: ≥ 98.0%

Colore e forma: White to off-white or pale yellow powder

Peso molecolare: 398.54

Ref: 7W-GX9422

Fursultiamine

CAS: 804-30-8

Formula: C₁₇H₂₆N₄O₃S₂

Purezza: >95.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 398.54

Ref: 3B-F1364

Fursultiamine

CAS: 804-30-8

Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.

Formula: C₁₇H₂₆N₄O₃S₂

Purezza: 99.63% - 99.90%

Colore e forma: Solid

Peso molecolare: 398.54

Ref: TM-T4552

Fursultiamine

Prodotto controllato

CAS: 804-30-8

Applications Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases.
References Park, W., et al.: Clin. Ther., 38, 2277 (2016); Kosaka, T., et al.: Cancer Sci., 104, 1017 (2013); Lonsdale, D., et al.: Med. Sci. Monit., 10, 199 (2004)

Formula: C₁₇H₂₆N₄O₃S₂

Colore e forma: Neat

Peso molecolare: 398.54

Ref: TR-F865235

Thiamine tetrahydrofurfuryl disulfide

CAS: 804-30-8

Thiamine tetrahydrofurfuryl disulfide is a thiamine derivative that has been shown to serve as a cofactor for enzymes such as peptidyl-prolyl cis-trans isomerase, which catalyzes the formation of peptide hormones. It also plays a role in the synthesis of polymers such as cellulose. Thiamine tetrahydrofurfuryl disulfide can be found in crystalline cellulose and is an important component of two-way crossover studies on peptide hormones. This drug has been shown to stimulate oxidative metabolism in cells and may have therapeutic potential for treating conditions associated with oxidative injury, such as stroke, head trauma, and heart attack.
Thiamine tetrahydrofurfuryl disulfide may also have a role in the development of inflammatory responses through its interaction with toll-like receptor 4 (TLR4).

Formula: C₁₇H₂₆N₄O₃S₂

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 398.55 g/mol

Ref: 3D-FT40945

FURSULTIAMINE

CAS: 804-30-8

Purezza: 98%

Peso molecolare: 398.5400085

Ref: 10-F806208