CAS 82586-52-5

Cloridrato di moexipril

Descrizione:

Cloridrato di moexipril è un inibitore dell'enzima di conversione dell'angiotensina (ACE) utilizzato principalmente nel trattamento dell'ipertensione. È un pro-farmaco che viene convertito nel corpo nella sua forma attiva, moexiprilato, che esercita i suoi effetti farmacologici inibendo la conversione dell'angiotensina I in angiotensina II, portando a vasodilatazione e riduzione della pressione sanguigna. La formula chimica di Cloridrato di moexipril include una struttura complessa con un derivato della prolina, che contribuisce alla sua efficacia e specificità. Viene tipicamente somministrato per via orale ed è noto per la sua emivita relativamente lunga, consentendo una somministrazione una volta al giorno. Gli effetti collaterali comuni possono includere vertigini, tosse e livelli elevati di potassio, tra gli altri. Come altri inibitori dell'ACE, è controindicato in pazienti con una storia di angioedema correlato a precedenti terapie con inibitori dell'ACE e deve essere usato con cautela in individui con compromissione renale. In generale, Cloridrato di moexipril è un importante agente terapeutico nella gestione della salute cardiovascolare.

Formula: C₂₇H₃₄N₂O₇·ClH

InChI: InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1

InChI key: InChIKey=JXRAXHBVZQZSIC-JKVLGAQCSA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2CC=3C(C[C@H]2C(O)=O)=CC(OC)=C(OC)C3.Cl

Sinonimi:

• (3S)-2-[(2S)-2-{[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisochinolin-3-carbons?urehydrochlorid
• (3S)-2-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• (3S)-2-{N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
• (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride (1:1)
• (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)
• (3S-(2(R*(R*)),3R*))-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-3-isoquinolinecarboxylic acid monohydrochloride
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, hydrochloride (1:1)
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1), (3S)-
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, monohydrochloride, (3S)-
• 3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, monohydrochloride, [3S-[2[R*(R*)],3R*]]-
• 3-isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, monohydrochloride
• Ci 925
• Moexipril HCl
• Primox
• Rs 10085-197
• Spm 925
• Univasc

Moexipril Hydrochloride

CAS: 82586-52-5

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₂₇H₃₄N₂O₇·HCl

Colore e forma: Powder

Peso molecolare: 498.2366

Ref: 45-1445426

Moexipril hydrochloride

CAS: 82586-52-5

Formula: C₂₇H₃₅N₂O₇Cl

Purezza: ≥ 98.0%

Colore e forma: Conflicting attributes defined

Peso molecolare: 535.03

Ref: 7W-GP1850

Moexipril HCl

CAS: 82586-52-5

Formula: C₂₇H₃₄N₂O₇·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 498.58 36.46

Ref: 4Z-M-311

Moexipril-d5 HCl

CAS: 1356929-49-1, 82586-52-5

Formula: C₂₇H₂₉D₅N₂O₇·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 503.61 36.46

Ref: 4Z-M-312

Moexipril hydrochloride

CAS: 82586-52-5

Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of

Formula: C₂₇H₃₄N₂O₇·HCl

Purezza: 97.8%

Colore e forma: A Fine White To Off-White Powder

Peso molecolare: 535.03

Ref: TM-T6595

Moexipril Hydrochloride

Prodotto controllato

CAS: 82586-52-5

Applications Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril.
References Edling, O., et al.: J. Pharmacol. Exp. Ther., 275, 854 (1995), White, W.B., et al.: J. Hum. Hypertens., 8, 917 (1994), Stimpel, M., et al.: Cardiology 87, 313 (1996)

Formula: C₂₇H₃₄N₂O₇·ClH

Colore e forma: Neat

Peso molecolare: 535.03

Ref: TR-M485350

Moexipril HCl

CAS: 82586-52-5

Inhibitor of angiotensin converting enzyme

Formula: C₂₇H₃₅ClN₂O₇

Purezza: Min. 95%

Colore e forma: Off-White Powder

Peso molecolare: 535.03 g/mol

Ref: 3D-FM26040

Moexipril HCl - Bio-X ™

CAS: 82586-52-5

Moexipril is an angiotensin converting enzyme inhibitor that is used for the treatment of hypertension. This drug is a prodrug for moexiprilat and works by relaxing the blood vessels causing them to widen and lowering blood pressure. Moexipril has been shown to be effective in treating metabolic disorders such as congestive heart failure.

Formula: C₂₇H₃₄N₂O₇

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 498.57 g/mol

Ref: 3D-BM164604