CAS 82586-55-8

Cloridrato di quinapril

Descrizione:

Cloridrato di quinapril è un inibitore dell'enzima di conversione dell'angiotensina (ACE) utilizzato principalmente nel trattamento dell'ipertensione e dell'insufficienza cardiaca. È una polvere cristallina bianca o bianco sporco solubile in acqua e presenta una formula molecolare che riflette la sua struttura complessa. La sostanza agisce inibendo la conversione dell'angiotensina I in angiotensina II, portando a vasodilatazione e riduzione della pressione sanguigna. Cloridrato di quinapril viene tipicamente somministrato per via orale ed è spesso prescritto in combinazione con altri agenti antipertensivi per migliorare l'efficacia terapeutica. La sua farmacocinetica prevede un'assorbimento rapido, con concentrazioni plasmatiche massime che si verificano entro poche ore dopo la somministrazione. Il farmaco viene metabolizzato nel fegato nella sua forma attiva, quinaprilato, che contribuisce ai suoi effetti antipertensivi. Gli effetti collaterali comuni possono includere vertigini, affaticamento e tosse, mentre effetti avversi gravi possono comportare compromissione renale e iperkaliemia. Come con qualsiasi farmaco, è essenziale che i pazienti consultino professionisti sanitari per una corretta dosaggio e monitoraggio.

Formula: C₂₅H₃₀N₂O₅·ClH

InChI: InChI=1S/C25H30N2O5.ClH/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30;/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30);1H/t17-,21-,22-;/m0./s1

InChI key: InChIKey=IBBLRJGOOANPTQ-JKVLGAQCSA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2[C@H](C(O)=O)CC=3C(C2)=CC=CC3.Cl

Sinonimi:

• (3S)-2-{N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, hydrochloride (1:1), (3S)-
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, (3S)-
• 3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, [3S-[2[R*(R*)],3R*]]-
• Accupril
• Accuprin
• Accupro
• Accupro 20
• Accupron
• Acequide
• Acequin
• Acuitel
• Acuprel
• Acupril
• Ci 906
• Korec
• Korectic
• Pd 109452-2
• Quinapril
• Quinapril hcl
• Quinazil
• Quinopril
• Quinapril hydrochloride
• QUINAPRIL HYDROCHLORIDE, RELATED COMPOUND B3-ISOQUINOLINECARBOXYLIC ACID, 2-[2-[(1-CARBOXY-3-PHENYLPROPYL)AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-,[3S-[2[R*(R*)],3R*]]-USP STANDARD
• QUINAPRIL HYDROCHLORIDE, RELATED COMPOUND A ETHYL[3S-[2(R*),3A,11A BETA]]-1,3,4,6,11,11A-HEXAHYDRO-3-METHYL-1,4-DIOXO-ALPHA-(2-PHENYLETHYL)-2H-PYRAZINO[1,2-B]ISOQUINOLINE-2-ACETATE USP STANDARD
• QuinaprilHclC25H30N205.HC1
• 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-, monohydrochloride, (3S)-(9CI)
• monohydrochloride,(3s-(2(r*(r*)),3r*))-henylpropyl)amino)-1-oxopropyl)
• CI-906, PD-109452-2, Accupril, Accuprin, Accupro
• (3S)-2-[(2S)-2-[[(1S)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-1-OXOPROPYL]-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID HYDROCHLORIDE

Quinapril hydrochloride, 98%

CAS: 82586-55-8

Angiotensin-converting enzyme inhibitor

Formula: C₂₅H₃₀N₂O₅•HCl

Purezza: 98%

Peso molecolare: 474.99

Ref: 02-J61913

Quinapril Hydrochloride

CAS: 82586-55-8

Colore e forma: Neat

Ref: 61-FOR0628.00

QUINAPRIL FOR SYSTEM SUITABILITY CRS

CAS: 82586-55-8

QUINAPRIL FOR SYSTEM SUITABILITY CRS

Formula: C₂₅H₃₁ClN₂O₅

Colore e forma: Powder

Peso molecolare: 474.977

Ref: 41-Y0001503

QUINAPRIL FOR PEAK IDENTIFICATION CRS

CAS: 82586-55-8

QUINAPRIL FOR PEAK IDENTIFICATION CRS

Formula: C₂₅H₃₁ClN₂O₅

Colore e forma: Powder

Peso molecolare: 474.977

Ref: 41-Y0001502

QUINAPRIL HYDROCHLORIDE CRS

CAS: 82586-55-8

QUINAPRIL HYDROCHLORIDE CRS

Formula: C₂₅H₃₁ClN₂O₅

Colore e forma: Powder

Peso molecolare: 474.977

Ref: 41-Y0001491

Quinapril hydrochloride

CAS: 82586-55-8

Quinapril hydrochloride

Formula: C₂₅H₃₀N₂O₅HCl

Purezza: 99.3%

Colore e forma: White

Peso molecolare: 474.19215

Ref: 47-1193

Quinapril Hydrochloride

CAS: 82586-55-8

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₂₅H₃₀N₂O₅·HCl

Colore e forma: Off-White Powder

Peso molecolare: 474.98

Ref: 45-1593401

Quinapril hydrochloride

CAS: 82586-55-8

Formula: C₂₅H₃₁ClN₂O₅

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 474.9770

Ref: IN-DA01BD2N

Quinapril hydrochloride

CAS: 82586-55-8

Quinapril HCl (PD-109452-2) treats hypertension and heart failure; low risk of liver enzyme elevations.

Formula: C₂₅H₃₁ClN₂O₅

Purezza: 98.05%

Colore e forma: White Crystalline Solid

Peso molecolare: 474.98

Ref: TM-T0805

Quinapril hydrochloride

CAS: 82586-55-8

Formula: C₂₅H₃₀N₂O₅HCl

Peso molecolare: 474.99

Ref: 7W-GP2644

Quinapril HCl

CAS: 82586-55-8

Formula: C₂₅H₃₀N₂O₅·HCl

Colore e forma: Pale Yellow Solid

Peso molecolare: 438.52 36.46

Ref: 4Z-Q-021

(S)-2-(((S)-1-Ethoxy-1-Oxo-4-Phenylbutan-2-Yl)-L-Alanyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride

CAS: 82586-55-8

(S)-2-(((S)-1-Ethoxy-1-Oxo-4-Phenylbutan-2-Yl)-L-Alanyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid Hydrochloride

Purezza: 99%

Peso molecolare: 474.98g/mol

Ref: 54-OR1008625

Quinapril-d5

CAS: 82586-55-8

Formula: C₂₅H₂₅D₅N₂O₅

Peso molecolare: 443.56

Ref: 4Z-Q-022

Quinapril Hydrochloride

Prodotto controllato

CAS: 82586-55-8

Formula: C₂₅H₃₀N₂O₅·ClH

Colore e forma: Neat

Peso molecolare: 474.98

Ref: 86-MM0628.00

Quinapril Hydrochloride

CAS: 82586-55-8

Formula: C₂₅H₃₀N₂O₅·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 474.98

Ref: 3B-Q0082

Quinapril Hydrochloride

Prodotto controllato

CAS: 82586-55-8

Applications Quinapril is an angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Klutchko, S., et al.: J. Med. Chem., 29, 1953 (1986), Holt, P., et al.: Eur. J. Clin. Pharmacol., 31, 9 (1986),

Formula: C₂₅H₃₀N₂O₅·ClH

Colore e forma: Neat

Peso molecolare: 474.98

Ref: TR-Q670000

Quinapril hydrochloride

CAS: 82586-55-8

Angiotensin-converting enzyme inhibitor

Formula: C₂₅H₃₁ClN₂O₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 474.98 g/mol

Ref: 3D-FQ27372

Quinapril HCl - Bio-X ™

CAS: 82586-55-8

Quinapril is an angiotensin-converting enzyme (ACE) inhibitor prodrug that is used to treat hypertension and congestive heart failure. It blocks the conversion of angiotensin I to angiotensin II, resulting in vasodilation which lowers blood pressure.

Formula: C₂₅H₃₀N₂O₅•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 474.98 g/mol

Ref: 3D-BQ164301