CAS 82911-69-1

N-(9-Fluorenilmetossicarbonilossi)succinimide

Descrizione:

N-(9-Fluorenilmetossicarbonilossi)succinimide, comunemente noto come FMOC-succinimide, è un composto chimico ampiamente utilizzato nella sintesi organica, in particolare nella chimica dei peptidi. Funziona come un gruppo protettivo per gli amminoacidi, consentendo reazioni selettive senza interferire con altri gruppi funzionali. La struttura presenta un moiety di succinimide legato a un gruppo 9-fluorenilmetossicarbonile (FMOC), noto per la sua stabilità in condizioni basiche e facilità di rimozione in condizioni acide leggere. Questo composto è tipicamente un solido bianco a bianco sporco ed è solubile in solventi organici come il diclorometano e il dimetilformamide. Le sue applicazioni si estendono oltre la sintesi dei peptidi per includere l'uso in varie reazioni di accoppiamento e come reagente nelle trasformazioni organiche. Il gruppo FMOC è preferito per la sua capacità di fornire un ambiente protettivo stabile mentre facilita le reazioni successive, rendendolo uno strumento prezioso nella chimica organica sintetica. Devono essere osservate precauzioni di sicurezza quando si maneggia questo composto, poiché può comportare rischi per la salute se inalato o ingerito.

Formula: C₁₉H₁₅NO₅

InChI: InChI=1/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2

InChI key: InChIKey=WMSUFWLPZLCIHP-UHFFFAOYSA-N

SMILES: C(OC(ON1C(=O)CCC1=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinonimi:

• (2,5-Dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
• (9H-Fluoren-9-yl)methyl succinimidyl carbonate
• (Fluorenylmethoxycarbonyl)hydroxysuccinimide ester
• 1-(9H-Fluorenylmethoxycarbonyloxy)-2,5-pyrrolidinedione
• 1-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]oxy]pyrrolidine-2,5-dione
• 1-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}pyrrolidine-2,5-dione
• 2,5-Dioxopyrrolidin-1-yl (9H-fluoren-9-yl)methyl carbonate
• 2,5-Pyrrolidinedione, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-
• 9-Fluorenylmethyl N-succinimidyl carbonate
• 9-Fluorenylmethyl succinimidyl carbonate
• 9-Fluorenylmethyl-N-hydroxysuccinimide
• Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 9H-fluoren-9-ylmethyl ester
• FMOC-ONSu
• Fluorenylmethoxycarbonyl N-hydroxysuccinimide
• Fmoc-N-hydroxysuccinimide
• Fmoc-N-hydroxysuccinimide ester
• Fmoc-Osu
• N-(9-Fluorenylmethoxy Carbonyloxy) succinimide
• N-(9-Fluorenylmethyloxycarbonyl) oxysuccinimide
• N-(9H-Fluoren-2-ylmethoxycarbonyloxy)succinimide
• N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide
• N-Fmoc-succinimide
• Succinimidyl (9-fluorenyl)methyl carbonate
• N-(9-FluorenylmethoxyCarbonyloxy) Succinimide
• N-(9-fluorenylmethoxycarbonyloxy)-succinimide
• N-(9-Fluorenylmethoxycarbonyloxy)succinimide
• N-(9-FLUORENYLMETHOXYCARBONYL)SUCCINIMIDE
• 9-FLUORENYLMETHYLOXYCARBONYL-N-HYDROXYSUCCINIMIDE
• 9-FLUORENYLMETHYL N-HYDROXYSUCCINIMIDYL CARBONATE
• CARBONIC ACID FLUORENYLMETHYL SUCCIN-N-YL-ESTER
• N-(9-FLUORENEMETHOXYCARBONYLOXY)-SUCCINIMIDE
• CARBONIC ACID 2,5-DIOXO-PYRROLIDIN-1-YL ESTER 9H-FLUOREN-9-YLMETHYL ESTER
• N-(9-FLUORENYLMETHYLOXYCARBONYLOXY)-SUCCINIMIDE
• FMOC-SU
• FLUORENYLMETHYL SUCCINIMIDYL CARBONATE
• 9-FLUORENMETHYL SUCCINIMIDYL CARBONATE

N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 98%

CAS: 82911-69-1

N-(9-Fluorenylmethoxycarbonyloxy)succinimide is the most efficient reagent for the selective preparation of N-(9-fluorenylmethoxycarbonyl) derivatives of hydroxy-amino acids. Dipeptide formation is lower than with the chloroformate, Fmoc-Cl. It is also employed in the synthesis of glycopeptides. Thi

Formula: C₁₉H₁₅NO₅

Purezza: 98%

Colore e forma: White, Powder

Peso molecolare: 337.33

Ref: 02-A13143

Fmoc-ONSU

CAS: 82911-69-1

Formula: C₁₉H₁₅NO₅

Purezza: 97%

Colore e forma: Powder or Crystalline Powder

Peso molecolare: 337.331

Ref: 10-F011742

Fmoc-OSu

CAS: 82911-69-1

Most efficient reagent for the selective preparation of Fmoc-derivatives of hydroxy amino acids in high yield. The advantage of Fmoc-OSu is that little or no oligopeptides are formed when amino acid derivatives are prepared. The use of this reagent in the synthesis of glycopeptides has been reported as well.

Formula: C₁₉H₁₅NO₅

Purezza: 99.8%

Colore e forma: White

Peso molecolare: 337.33

Ref: 01-4006805

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

CAS: 82911-69-1

Formula: C₁₉H₁₅NO₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 337.3261

Ref: IN-DA0034XN

Fmoc N-hydroxysuccinimide ester

CAS: 82911-69-1

Formula: C₁₉H₁₅NO₅

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 337.34

Ref: 7W-GM5706

N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide

CAS: 82911-69-1

Formula: C₁₉H₁₅NO₅

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 337.33

Ref: 3B-F0239

1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}oxy)pyrrolidine-2,5-dione

CAS: 82911-69-1

1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}oxy)pyrrolidine-2,5-dione

Formula: C₁₉H₁₅NO₅

Purezza: ≥95%

Colore e forma: white solid

Peso molecolare: 337.32609g/mol

Ref: 54-OR18352

Fmoc-Osu (N-Fmoc-succinimide)

CAS: 82911-69-1

Formula: C₁₉H₁₅NO₅

Peso molecolare: 337.33

Ref: 4Z-S-131003

Fmoc N-Hydroxysuccinimide Ester

CAS: 82911-69-1

Stability Moisture Sensitive
Applications Used in conjunction with Isothiocyanate to conduct partial Edman Degradation on biologically active peptides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Heidenreich, O., et al.: J. Biol. Chem., 269, 2131 (1994), Kothe, U., et al.: Anal. Biochem., 356, 148 (2006), Thakkar, A., et al.: Anal. Chem., 78, 5935 (2006),

Formula: C₁₉H₁₅NO₅

Colore e forma: Neat

Peso molecolare: 337.33

Ref: TR-F634000

Fmoc-OSu

CAS: 82911-69-1

Fmoc-OSu is a matrix that can be used as an absorption enhancer in biological and biochemical studies. The ester hydrochloride form of Fmoc-OSu is soluble in water and methanol, but not in organic solvents such as chloroform or ether. Fmoc-OSu is also a fluorescent derivative that can be used to label glycan structures in primary cells. The reaction solution with anhydrous sodium carbonate and glycan produces a cyclic peptide. This reaction is carried out at room temperature with analytical methods using a spectrophotometer or high performance liquid chromatography (HPLC).

Formula: C₁₉H₁₅NO₅

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 337.33 g/mol

Ref: 3D-FF10663

FMOC-OSu extrapure AR, 99%

CAS: 82911-69-1

Formula: C₁₉H₁₅NO₅

Purezza: min. 99.0%

Colore e forma: White to off - white, Powder

Peso molecolare: 337.33

Ref: SR-79235

Fmoc-OSu

CAS: 82911-69-1

Fmoc-OSu is a synthetic amino acid that is used in the synthesis of peptides and other biomolecules. It can be synthesized by solid-phase peptide synthesis using Fmoc chemistry, which involves an acid-labile protecting group. Fmoc-OSu has been shown to inhibit cancer cell growth, although its mechanism is not known.
Fmoc-OSu has been shown to have anti-inflammatory effects by inhibiting the proinflammatory cytokine TNFα.
Fmoc-OSu has also been shown to have glycan binding properties, which may be due to its ability to bind with sialic acid residues on glycoproteins or glycolipids.

Formula: C₁₉H₁₅NO₅

Purezza: Min. 98.0 Area-%

Peso molecolare: 337.33 g/mol

Ref: 3D-KFS-1042-PI