CAS 83432-20-6

3-Amino-4-hydroxy-6-methyl-2H-pyran-2-one

CAS: 83432-20-6

3-Amino-4-hydroxy-6-methyl-2H-pyran-2-one is a metabotropic glutamate receptor ligand that has a chemical structure similar to 7-amino-4,7 -dimethylcoumarin. It binds to the metabotropic glutamate receptor and blocks the binding of glutamate in synapses, inhibiting its normal activity. 3AAMC is an allosteric modulator of the metabotropic glutamate receptor because it binds at a site different from that which binds glutamate. This type of modulation leads to changes in the sensitivity of the receptor to other ligands such as AMPA. 3AAMC also inhibits amine uptake and dielectrophile alkylation by chloride ions, which may lead to neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.

Formula: C₆H₇NO₃

Purezza: Min. 95%

Peso molecolare: 141.12 g/mol

Ref: 3D-IDA43220