CAS 83881-51-0

Cetirizina

Descrizione:

Cetirizina è un antistaminico comunemente usato per alleviare i sintomi allergici come starnuti, naso che cola e occhi pruriginosi. È classificato come un antistaminico di seconda generazione, il che significa che è meno probabile che causi sedazione rispetto agli antistaminici di prima generazione. Cetirizina agisce inibendo selettivamente il recettore H1 dell'istamina, riducendo così gli effetti dell'istamina nel corpo. La sua formula chimica è C21H25ClN2O3S e ha un peso molecolare di circa 388,96 g/mol. Cetirizina viene tipicamente somministrato per via orale ed è noto per la sua durata d'azione relativamente lunga, rendendolo efficace per una somministrazione una volta al giorno. La sostanza è generalmente ben tollerata, anche se alcune persone possono sperimentare effetti collaterali come sonnolenza, bocca secca o disturbi gastrointestinali. Cetirizina è anche usato nella gestione dell'orticaria cronica (ponfi) ed è disponibile in varie formulazioni, tra cui compresse, sciroppo e forme masticabili. Il suo profilo di sicurezza ed efficacia lo rende una scelta popolare per il trattamento delle condizioni allergiche.

Formula: C₂₁H₂₅ClN₂O₃

InChI: InChI=1/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)

InChI key: InChIKey=ZKLPARSLTMPFCP-UHFFFAOYSA-N

SMILES: C(N1CCN(CCOCC(O)=O)CC1)(C2=CC=C(Cl)C=C2)C3=CC=CC=C3

Sinonimi:

• 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid
• Acetic acid, 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
• Acetic acid, [2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
• 2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid
• Cetirizine
• (±)-Cetirizine
• (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)aceticacid
• Zirtek
• Zyrlex
• (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-aceticaci
• Cetirizine Hydrochloride BP
• vidix
• CERTIRIZINE 2HCL
• Cetrizinehydrochloride
• 2-[2-[4-(4-Chlorobenzhydryl)-1-piperazinyl]ethoxy]acetic acid
• (2-(4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL)-ETHOXY)-ACETIC ACID
• Reactine
• 2-[4-(4-Chlorobenzhydryl)-1-piperazinyl]ethoxyacetic acid
• Cetirizine (Cetrizine) Di HCl
• Formistin
• CETIRIZINE IMPURITY A(RS)-1-[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE EPC(CRM STANDARD)
• (RS)-2-[2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride

Cetirizine Dihydrochloride

CAS: 83881-51-0, 83881-52-1

Formula: C₂₁H₂₅ClN₂O₃·2HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 461.81

Ref: 3B-C2316

2-[2-[4-[(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrichloride

CAS: 83881-51-0

Formula: C₂₁H₂₅ClN₂O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 388.8878

Ref: IN-DA019CL1

2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid

CAS: 83881-51-0

2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid

Purezza: 98%

Peso molecolare: 388.9g/mol

Ref: 54-OR1059435

Cetirizine

CAS: 83881-51-0

Cetirizine is a non-sedating h1 antagonist that is used to treat allergic rhinitis and other allergic conditions. Cetirizine has been shown to produce statistically significant reductions in eosinophil cationic protein (ECP) in experimental models of allergic inflammation. The clinical significance of this finding remains unclear, but the results suggest that cetirizine may have anti-inflammatory effects. Cetirizine is metabolized by cytochrome P450 enzymes, including CYP3A4, which can lead to drug interactions with other pharmaceuticals. Low doses of cetirizine were found to inhibit 5-ht2 receptors in rats, which may be responsible for its sedative effects. Cetirizine was also found to be an effective wastewater treatment agent because it inhibits the growth of bacteria such as Escherichia coli and Pseudomonas aeruginosa.

Formula: C₂₁H₂₅ClN₂O₃

Purezza: Min. 95%

Peso molecolare: 388.89 g/mol

Ref: 3D-IDA88151

Levocetirizine Impurity 20

CAS: 83881-51-0

Formula: C₂₁H₂₅ClN₂O₃

Peso molecolare: 388.89

Ref: ST-EA-CP-L15038