CAS 83905-01-5

Azitromicina

Descrizione:

Azitromicina è un antibiotico macrolide caratterizzato dalla sua attività ad ampio spettro contro varie infezioni batteriche. È derivato dall'eritromicina ed è noto per la sua struttura unica, che include un grande anello di lattone e diversi moieties di zucchero. Azitromicina viene tipicamente somministrato per via orale ed è notevole per la sua lunga emivita, che consente una somministrazione una volta al giorno e corsi di trattamento più brevi rispetto ad altri antibiotici. Agisce inibendo la sintesi proteica batterica legandosi alla subunità ribosomiale 50S, prevenendo efficacemente la crescita dei batteri. Azitromicina è efficace contro una gamma di patogeni, inclusi quelli responsabili di infezioni respiratorie, infezioni cutanee e malattie sessualmente trasmissibili. È generalmente ben tollerato, con effetti collaterali comuni che includono disturbi gastrointestinali. Inoltre, ha proprietà anti-infiammatorie, che possono essere utili nel trattamento di alcune condizioni oltre alle infezioni batteriche. La sua farmacocinetica, che include una buona penetrazione nei tessuti e accumulo nelle cellule, contribuisce alla sua efficacia nel trattamento delle infezioni. Azitromicina è anche incluso nei regimi di trattamento per alcune infezioni atipiche ed è spesso utilizzato in terapie combinate.

Formula: C₃₈H₇₂N₂O₁₂

InChI: InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

InChI key: InChIKey=MQTOSJVFKKJCRP-BICOPXKESA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3

Sinonimi:

• (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
• (2R,3S,4R,5S,6R,8R,11S,12R,13R,14S)-5-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-6,12,13-trihydroxy-3-[(2S,4R,5S,6R)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-2,4,6,8,10,11,13-heptamethyl-15-oxa-10-azacyclopentadecan-1-one
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-
• 1-Oxa-6-azacyclopentadecan-15-one,13-((2,6-dideoxy-3-C-methyl-1-3-O-methyl-alpha-L-ribo-hexopyranosyl)-oxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-((3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy)
• 11-(4-Dimethylamino-3-Hydroxy-6-Methyl-Oxan-2-Yl)Oxy-2-Ethyl-3,4,10-Tr
• 9-Deoxo-9-methyl-9a-aza-9-homoerythromycin A
• 9-Deoxo-9a-methyl-9a-aza-9a-homoetrythromycin A
• 9-deoxo-9a-methyl-9a-aza-homoerythromycin A
• Aruzilina
• Arzomicin
• Auricin
• Auricin (polyketide antibiotic)
• AzaSite
• Azadose
• Azatril
• Azee
• Azenil
• Azimin
• Aziromycin
• Azisara
• Azithral
• Azithrocin
• Azithromycin A
• Azithromycine
• Azitrocin
• Azitromax
• Aziwin
• Aziwok
• Azomycin
• Azomycin (macrolide)
• Aztrin
• Cp 62993
• Durasite
• Hemomycin
• Macromycin
• Macrozit
• N-methyl-11-aza-10-deoxo-10-dihydroerythromycin A
• Sanhe
• Setron
• Shimen
• Sumamed
• Sumazid
• Tobil
• Tridosil
• Tromix
• Trozocina
• Ultreon
• Xithron
• Xithrone
• Xz 405
• Xz 450
• Zeto
• Zi-Factor
• Zifin
• Zistic
• Zithromac
• Zithromax
• Zithromax IV
• Zitrim
• Zitrocin
• Zitromax
• Zythromax

Azithromycin Dihydrate

CAS: 117772-70-0, 83905-01-5

Formula: C₃₈H₇₂N₂O₁₂·2H₂O

Purezza: >98.0%(N)

Colore e forma: White powder to crystal

Peso molecolare: 785.03

Ref: 3B-A2076

Azithromycin

CAS: 83905-01-5

Colore e forma: Neat

Ref: 61-FOR1075.00

1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

CAS: 83905-01-5

Formula: C₃₈H₇₆N₂O₁₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 785.0150

Ref: IN-DA0036GY

Azithromycin

CAS: 83905-01-5

Azithromycin

Purezza: ≥98%

Peso molecolare: 748.98g/mol

Ref: 54-BUP15115

Azithromycin

CAS: 83905-01-5

Formula: C₃₈H₇₂N₂O₁₂

Colore e forma: White To Off-White Solid

Peso molecolare: 749.00

Ref: 4Z-A-2617

Azithromycin

CAS: 83905-01-5

Azithromycin

Formula: C₃₈H₇₂N₂O₁₂

Purezza: By hplc: 97.7% by area (Typical Value in Batch COA)

Colore e forma: white crystalline powder

Peso molecolare: 748.98g/mol

Ref: 54-BIA0165

Azithromycin-13C-d3

CAS: 83905-01-5

Formula: C₃₇₁₃CH₆₉D₃N₂O₁₂

Colore e forma: White To Off-White Solid

Peso molecolare: 753.01

Ref: 4Z-A-261

Azithromycin

Prodotto controllato

CAS: 83905-01-5

Formula: C₃₈H₇₂N₂O₁₂

Colore e forma: Neat

Peso molecolare: 748.98

Ref: 04-C10385990

Azithromycin

Prodotto controllato

CAS: 83905-01-5

Formula: C₃₈H₇₂N₂O₁₂

Colore e forma: Neat

Peso molecolare: 748.98

Ref: 86-MM1075.00

GB 31660.1-2019 Macrolide Antibiotics Mixture 167 100 µg/mL in Methanol

Prodotto controllato

CAS: 114-07-8, 1401-69-0, 16846-24-5, 2751-09-9, 69-23-8, 8025-81-8, 81103-11-9, 83905-01-5, 93952-07-9

Colore e forma: Mixture

Ref: 04-A50000167ME

Azithromycin

CAS: 83905-01-5

Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!

Formula: C₃₈H₇₂N₂O₁₂

Purezza: 99.9% - 99.97%

Colore e forma: White To Off-White Solid Crystalline

Peso molecolare: 748.98

Ref: TM-T6401

Azithromycin

CAS: 83905-01-5

Applications Azithromycin is an azalide macrolide antibiotic.
References Hunter, R., et al.: J. Vet. Pharmacol. Ther., 26, 117 (2003);

Formula: C₃₈H₇₂N₂O₁₂

Colore e forma: Neat

Peso molecolare: 748.98

Ref: TR-A927018

Azithromycin-d5

Prodotto controllato

CAS: 83905-01-5

Applications Azithromycin-d5, is the labeled analogue Azithromycin (A927000), a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
References Langtry, H.D., et al.: Drugs, 56, 273 (1998),

Formula: C₃₈H₆₇D₅N₂O₁₂

Colore e forma: Neat

Peso molecolare: 754.02

Ref: TR-A927004

Azithromycin-13CD3

Prodotto controllato

CAS: 83905-01-5

Applications Labelled Azithromycin, a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.
References Langtry, H.D., et al.: Drugs, 56, 273 (1998),

Formula: C₃₇₁₃CH₆₉D₃N₂O₁₂

Colore e forma: Neat

Peso molecolare: 753.0

Ref: TR-A927003

Azithromycin

CAS: 83905-01-5

A broad-spectrum antibiotic of macrolide class which targets 50S ribosome subunit and inhibits protein synthesis. Azithromycin is a semi-synthetic acid-stable derivative of erythromycin. In vitro, azithromycin is more efficient than erythromycin in some Gram-negative organisms such as Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, Neisseria gonorrhoeae and Borrelia burgdorferi.

Formula: C₃₈H₇₂N₂O₁₂

Purezza: 945.0 To 1030.0 U/Mg

Colore e forma: White Powder

Peso molecolare: 748.98 g/mol

Ref: 3D-AD29657

Azithromycin, Antibiotic for Culture Media Use Only

CAS: 83905-01-5

Azithromycin is a fine chemical that is useful as a scaffold, building block, and intermediate. Azithromycin has been used in research to study the structure of enzymes and other proteins. It is also useful as a reaction component in organic synthesis. This compound has many uses including as a reagent and as a speciality chemical. Azithromycin is used to produce high-quality laboratory chemicals for use in research.

Formula: C₃₈H₇₂N₂O₁₂

Purezza: Min. 97.0 Area-%

Peso molecolare: 748.98 g/mol

Ref: 3D-A-9941