CAS 84-36-6

Sirocingopina

Descrizione:

Sirocingopina è un composto organico classificato come un alcaloide, derivato principalmente dalla specie vegetale *Sirocingopina* e piante correlate. È noto per la sua complessità strutturale, caratterizzata da un quadro biciclico che include un anello di piperidina. Il composto mostra una gamma di attività biologiche, inclusi potenziali effetti analgesici e antipertensivi, rendendolo di interesse nella ricerca farmacologica. Sirocingopina è tipicamente caratterizzato dalla sua solubilità in solventi organici, mentre la sua solubilità in acqua è limitata. Il composto ha un peso molecolare relativamente basso ed è spesso studiato per le sue interazioni con vari obiettivi biologici, inclusi recettori ed enzimi. Le sue proprietà chimiche, come il punto di fusione e il punto di ebollizione, sono influenzate dalla sua struttura molecolare e dai gruppi funzionali. Come molti alcaloidi, Sirocingopina può anche mostrare proprietà chirali, portando a diverse attività biologiche a seconda della sua stereochimica. In generale, Sirocingopina rappresenta un'area significativa di studio nella chimica medicinale e nella ricerca di prodotti naturali.

Formula: C₃₅H₄₂N₂O₁₁

InChI: InChI=1S/C35H42N2O11/c1-7-46-35(40)48-31-26(42-3)12-18(13-27(31)43-4)33(38)47-28-14-19-17-37-11-10-22-21-9-8-20(41-2)15-24(21)36-30(22)25(37)16-23(19)29(32(28)44-5)34(39)45-6/h8-9,12-13,15,19,23,25,28-29,32,36H,7,10-11,14,16-17H2,1-6H3/t19-,23+,25-,28-,29+,32+/m1/s1

InChI key: InChIKey=ZCDNRPPFBQDQHR-SSYATKPKSA-N

SMILES: C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)[C@@H]1OC)[H])[H])[H]

Sinonimi:

• (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(éthoxycarbonyl)oxy]-3,5-diméthoxybenzoyl}oxy)-2,11-diméthoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodécahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoléine-1-carboxylate de méthyle
• (3Bêta,16Bêta,17Alpha,18Bêta,20Alpha)-18-({4-[(Éthoxycarbonyl)Oxy]-3,5-Diméthoxybenzoyl}Oxy)-11,17-Diméthoxyyohimban-16-Carboxylate De Méthyle
• (3b,16b,17a,18b,20a)-18-[[4-[(Ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxyyohimban-16-carboxylic Acid Methyl Ester
• 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester)
• Carbethoxysyringoyl Methyl Reserpate
• Carbethoxysyringoyl methylreserpate
• Hf 41T
• Isotense
• Londomin
• Methyl (1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-({[4-{[(Ethyloxy)Carbonyl]Oxy}-3,5-Bis(Methyloxy)Phenyl]Carbonyl}Oxy)-11,17-Bis(Methyloxy)Yohimban-16-Carboxylate
• Methyl (3Beta,16Beta,17Alpha,18Beta,20Alpha)-18-[({4-[(Ethoxycarbonyl)Oxy]-3,5-Dimethoxyphenyl}Carbonyl)Oxy]-11,17-Dimethoxyyohimban-16-Carboxylate
• Methyl (3beta,16beta,17alpha,18beta,20alpha)-18-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-11,17-dimethoxyyohimban-16-carboxylate
• Methyl carbethoxysyringoyl reserpate
• Methyl reserpate ester of syringic acid ethyl carbonate
• Methyl-(1S,2R,3R,4aS,13bR,14aS)-3-({4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl}oxy)-2,11-dimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isochinolin-1-carboxylat
• NSC 77030
• Raunova
• Reserpic acid, methyl ester, ester with syringic acid, ethyl carbonate
• Seniramin
• Singoserp
• Siringina
• Sml 1908
• Su 3118
• Syringic acid ethyl carbonate ester with methyl reserpate
• Syringopine
• Syrosingopin

Syrosingopine

CAS: 84-36-6

Syrosingopine analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₃₅H₄₂N₂O₁₁

Purezza: (HPLC) ≥90%

Colore e forma: Powder

Peso molecolare: 666.73

Ref: 11-1691

Syrosingopine

CAS: 84-36-6

Syrosingopine

Purezza: ≥98%

Peso molecolare: 666.71g/mol

Ref: 54-BUP07583

Syrosingopine

CAS: 84-36-6

Syrosingopine is a dual inhibitor of MCT1 and MCT4, 60 times more potent against MCT4, preventing lactate and H+ efflux.Cost-effective and quality-assured.

Formula: C₃₅H₄₂N₂O₁₁

Purezza: 99.25% - 99.78%

Colore e forma: Solid

Peso molecolare: 666.71

Ref: TM-TN2252

Syrosingopine

Prodotto controllato

CAS: 84-36-6

Applications Syrosingopine (CAS# 84-36-6) is a pharmaceutical used to treat hypertension.
References Woods, J. W.; et al.: Journal of Clinical Investigation, 39, 1813 (1960).

Formula: C₃₅H₄₂N₂O₁₁

Purezza: >90%

Colore e forma: Neat

Peso molecolare: 666.71

Ref: TR-S920068

Syrosingopine

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Formula: C₃₅H₄₂N₂O₁₁

Purezza: Min. 90 Area-%

Colore e forma: White Powder

Peso molecolare: 666.71 g/mol

Ref: 3D-FS65931

Syrosingopine - Bio-X ™

CAS: 84-36-6

Inhibitor of vesicular monoamine transporters with anti-hypertensive properties. Syrosingopine is also inhibitor of monocarboxylate transporters MCT1 and MCT4 and has 60-fold higher potency on MCT4. Syrosingopine inhibits lactate export from cells, causing glycolytic blockade, ATP depletion and cell death. Syrosingopine was shown to sensitise cancer cells to metformin treatment and potentiate its anti-cancer activity.

Formula: C₃₅H₄₂N₂O₁₁

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 666.72 g/mol

Ref: 3D-BS300129

SYROSINGOPINE

CAS: 84-36-6

Formula: C₃₅H₄₂N₂O₁₁

Purezza: %

Colore e forma: Solid

Peso molecolare: 666.7148

Ref: IN-DA00G2SK

Syrosingopine

CAS: 84-36-6

Colore e forma: Neat

Ref: 61-FOR1970.00