CAS 84676-89-1

Astragaloside II

Descrizione:

Astragaloside II, con il numero CAS 84676-89-1, è un glicoside naturale derivato principalmente dalla radice di Astragalus membranaceus, una pianta comunemente utilizzata nella medicina tradizionale. Questo composto è caratterizzato dalla sua composizione strutturale, che include una porzione di zucchero legata a un aglicone steroideo. Astragaloside II è noto per le sue potenziali proprietà farmacologiche, inclusi effetti immunomodulatori, anti-infiammatori e antiossidanti. È stato studiato per il suo ruolo nel migliorare la funzione immunitaria e promuovere la salute cellulare. Inoltre, la ricerca suggerisce che potrebbe avere effetti protettivi contro lo stress ossidativo e potrebbe supportare la salute cardiovascolare. Il composto è tipicamente solubile in solventi polari e la sua stabilità può essere influenzata da fattori come pH e temperatura. Come composto bioattivo, Astragaloside II è di interesse sia nella ricerca farmacologica che nella medicina erboristica, sebbene siano necessari ulteriori studi per chiarire completamente i suoi meccanismi d'azione e il potenziale terapeutico.

Formula: C₄₃H₇₀O₁₅

InChI: InChI=1/C43H70O15/c1-21(45)54-29-28(48)23(47)19-53-34(29)58-43(52)32(49)25(18-44)56-35(33(43)50)55-24-16-26-39(7)17-22(46)30(40(8)13-10-27(57-40)37(4,5)51)38(39,6)14-15-41(26)20-42(41)12-9-11-36(2,3)31(24)42/h22-35,44,46-52H,9-20H2,1-8H3/t22-,23+,24-,25+,26?,27-,28-,29+,30-,31?,32+,33-,34-,35+,38+,39-,40+,41?,42+,43+/m0/s1

InChI key: InChIKey=AYWNHWGQTMCQIV-PENCHUSISA-N

SMILES: C[C@]12[C@]3([C@]4([C@]5(C4)[C@@]([C@@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C3)(C(C)(C)[C@@H](O[C@H]7[C@H](OC(C)=O)[C@@H](O)[C@H](O)CO7)CC5)[H])CC[C@]1(C)[C@]([C@@H](O)C2)([C@]8(C)O[C@H](C(C)(C)O)CC8)[H])[H]

Sinonimi:

• (2S,3R,4S,5R)-4,5-dihydroxy-2-{[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-2-({(1R,2S,3aS,5S,9aR,12aR)-2-hydroxy-1-[(2R,5S)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl]-3a,6,6,12a-tetramethyltetradecahydro-1H-cyclopenta[a]cyclopropa[e]phenanthren-5-yl}oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}tetrahydro-2H-pyran-3-yl acetate (non-preferred name)
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-<span class="text-smallcaps">D</smallcap>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-<smallcap>D</span>-glucopyranoside
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• 9,19-Cyclolanostane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Astrasieversianin VIII
• NSC 641295
• astragalosideⅡ
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-<smallcap>D</span>-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, β-D-glucopyranoside deriv.
• (3β,6α,16β,20R,24S)-3-[(2-O-Acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl β-D-glucopyranoside
• Astragaloside II
• 9,19-Cyclolanostane, β-D-glucopyranoside deriv.
• β-D-Glucopyranoside, (3β,6α,16β,20R,24S)-3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragaloside II
• (3b,6a,16b,20r,24s)-3-((2-o-acetyl-beta-d-xylopyranosyl)oxy)-20,24-epoxy-16,25-dihydroxy-9,19-cyclolanostan-6-yl beta-d-glucopyranoside
• Astragaloside II USP/EP/BP
• Cyclosiversioside D
• Astragaloside II 84676-89-1
• Astragaloside II (Astrasieversianin VIII)
• Astragaloside B
• 16,25-dihydroxy-9,19-cyclolanostan-6-yl
• Astragalin Astragaloside II
• Cyclosieversioside D
• ASTRAGALOSIDE II(SH)
• 3-[(2-O-acetyl-β-D-xylopyranosyl)oxy]-20,24-epoxy-

β-​D-​Glucopyranoside, (3β,​6α,​16β,​20R,​24S)​-​3-​[(2-​O-​acetyl-​β-​D-​xylopyranosyl)​oxy]​-​20,​24-​epoxy-​16,​25-​dihydroxy-​9,​19-​cyclolanostan-​6-​yl

CAS: 84676-89-1

Formula: C₄₃H₇₀O₁₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 827.0069

Ref: IN-DA003NXK

Astragaloside II

CAS: 84676-89-1

Astragaloside II

Purezza: ≥98%

Peso molecolare: 827.01g/mol

Ref: 54-BUP02941

Astragaloside II

CAS: 84676-89-1

Ref: 7W-GC0586

Astragaloside II

CAS: 84676-89-1

Astragaloside II can downregulate the expression of the P-gp and mdr1 gene, suppress phosphorylation of extracellular signal regulated kinase 1/2, p38 and c-Jun N-terminal kinase, suggests that Astragaloside II is a potent multidrug resistance (MDR) reversal agent and may be a potential adjunctive agent for hepatic cancer chemotherapy.

Formula: C₄₃H₇₀O₁₅

Purezza: 95%~99%

Colore e forma: Powder

Peso molecolare: 827.018

Ref: BP-BP0211

Astragaloside II

CAS: 84676-89-1

Astragaloside II: Potent for MDR, hepatic cancer therapy; boosts osteogenesis via BMP-2/MAPK, Smad1/5/8 pathways.

Formula: C₄₃H₇₀O₁₅

Purezza: 98.54% - 99.7%

Colore e forma: Solid

Peso molecolare: 827.01

Ref: TM-T3924

Astragaloside ii

CAS: 84676-89-1

Natural glycoside

Formula: C₄₃H₇₀O₁₅

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 827.02

Ref: 5G-89573

Astragaloside II

Prodotto controllato

CAS: 84676-89-1

Applications Astragaloside II has cardioprotective effects as well as causing improvement in cognitive function. Used in the prevention of cardio-cerebral vascular diseases.
References Shaw, L et al.: PLoS One, 7, e3848 (2012); Kong, X. et al.: Int. J. Mol. Med., 29, 1090 (2012);

Formula: C₄₃H₇₀O₁₅

Colore e forma: Neat

Peso molecolare: 827.01

Ref: TR-A790140

Astragaloside II

CAS: 84676-89-1

Astragaloside II is a natural compound that has been shown to have anti-inflammatory effects in vitro and in vivo. Astragaloside II inhibits the production of inflammatory mediators by inhibiting phosphodiesterase and cyclooxygenase pathways. It also has a matrix effect on the cells, which may be due to its ability to activate protein kinase C. This compound also has an analytical method, which consists of HPLC with UV detection at 210 nm.

Formula: C₄₃H₇₀O₁₅

Purezza: Min. 95%

Colore e forma: White To Off-White Solid

Peso molecolare: 827.01 g/mol

Ref: 3D-MA09407