CAS 849214-04-6

c-GpAp

CAS: 849214-04-6

Formula: C₂₀H₂₄N₁₀O₁₃P₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 674.4113

Ref: IN-DA00G3D7

2-Amino-9-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecin-2-yl)-3,9-dihy

CAS: 849214-04-6

2-Amino-9-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecin-2-yl)-3,9-dihy

Purezza: 98%

Peso molecolare: 674.42g/mol

Ref: 54-OR1067119

cGAMP

CAS: 849214-04-6

cGAMP is an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. It also is a STING ligand.

Formula: C₂₀H₂₄N₁₀O₁₃P₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 674.41

Ref: TM-T13606

cGAMP disodium salt

CAS: 849214-04-6

Formula: C₂₀H₂₄N₁₀O₁₃P₂·2Na

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 693.4

Ref: 7W-GL2101

c-GpAp

Prodotto controllato

CAS: 849214-04-6

Applications c-GpAp induces the production of interferons, a usual response to triggers in the cytoplasm of mammalian cells by the presence of DNA.
References Sun, L. et al.: Science, 339, 786 (2013);

Formula: C₂₀H₂₄N₁₀O₁₃P₂

Colore e forma: Neat

Peso molecolare: 674.41

Ref: TR-G110500

3',3'-Cyclic guanosine monophosphate-adenosine monophosphate

CAS: 849214-04-6

3',3'-Cyclic guanosine monophosphate-adenosine monophosphate is a molecule that is a stimulator of lymphocytic leukemia. It has been shown to induce chronic lymphocytic leukemia in mice and humans, which is an indication of its clinical relevance. 3',3'-Cyclic guanosine monophosphate-adenosine monophosphate induces cancer by inhibiting the production of cyclic nucleotide phosphodiesterases, which are enzymes that break down cyclic nucleotides. This leads to elevated levels of cyclic nucleotides and an increase in intracellular cAMP levels. The anticancer effect of 3',3'-cyclic guanosine monophosphate-adenosine monophosphate may also be due to its ability to inhibit the growth factor activity of staphylococcus aureus.

Formula: C₂₀H₂₂N₁₀O₁₃P₂·2Na

Purezza: Min. 95%

Peso molecolare: 718.38 g/mol

Ref: 3D-NC137624