CAS 85622-93-1
:Temozolomide
Descrizione:
Temozolomide è un agente alchilante orale utilizzato principalmente nel trattamento di alcuni tipi di tumori cerebrali, in particolare il glioblastoma multiforme e l'astrocitoma anaplastico. La sua formula chimica è C6H6N4O2 ed è classificato come un profarmaco, il che significa che viene metabolizzato nel corpo nella sua forma attiva, che poi esercita i suoi effetti terapeutici. Temozolomide agisce metilando il DNA, portando all'interruzione della replicazione del DNA e, infine, inducendo l'apoptosi nelle cellule cancerose a rapida divisione. La sostanza viene tipicamente somministrata in forma di capsule ed è nota per la sua capacità di attraversare la barriera ematoencefalica, rendendola efficace per i tumori del sistema nervoso centrale. Temozolomide è generalmente ben tollerato, ma può causare effetti collaterali come nausea, vomito e mielosoppressione. La sua farmacocinetica implica un rapido assorbimento e metabolismo, con una emivita che consente schemi di dosaggio convenienti. In generale, Temozolomide rappresenta un significativo progresso nella gestione chemioterapica dei tumori cerebrali maligni.
Formula:C6H6N6O2
InChI:InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)
InChI key:InChIKey=BPEGJWRSRHCHSN-UHFFFAOYSA-N
SMILES:C(N)(=O)C1=C2N(C(=O)N(C)N=N2)C=N1
Sinonimi:- 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide
- 3-Methyl-4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazine-8-carboxylic acid amide
- 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
- 3-Methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide
- 3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxamide
- 3-Methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
- 3-Methyl-8-carbamoylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
- 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide
- 8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
- Ccrg 81045
- Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
- M and B 39831
- Mb 39831
- Methazolastone
- NSC 362856
- Sch 52365
- T 2577
- Temodal
- Temodar
- Temomedac
- Vedi altri sinonimi
Ordinare per
Purezza (%)
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100
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90
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95
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14 prodotti.
Temozolomide
CAS:Formula:C6H6N6O2Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light red powder to crystalPeso molecolare:194.15Temozolomide
CAS:TemozolomideFormula:C6H6N6O2Purezza:99.5%Colore e forma:WhitePeso molecolare:194.05522Temozolomide
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, excluding aromatic or modified aromaticFormula:C6H6N6O2Colore e forma:PowderPeso molecolare:194.055223-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carboxamide
CAS:Formula:C6H6N6O2Purezza:98%Colore e forma:SolidPeso molecolare:194.1508Temozolomide
CAS:Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity.Formula:C6H6N6O2Purezza:98% - 99.87%Colore e forma:Off-White To Light-Pink Crystalline SolidPeso molecolare:194.15Temozolomide
CAS:TemozolomideFormula:C6H6N6O2Purezza:98%Colore e forma: white solidPeso molecolare:194.15g/molTemozolomide
CAS:Formula:C6H6N6O2Purezza:≥ 98.0%Colore e forma:White to light-brown or pink powderPeso molecolare:194.153-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
CAS:Formula:C6H6N6O2Purezza:95%Colore e forma:SolidPeso molecolare:194.154Temozolomide
CAS:<p>Temozolomide is a cancer drug that belongs to the class of alkylating agents. It has been shown to have anticancer activity against human tumor cells in vitro. Temozolomide induces cell death by activating the apoptotic pathway. This drug also inhibits the cell cycle and blocks the G2-M phase, resulting in accumulation of cells at this point in the cell cycle. Temozolomide has been studied for its effects for cancer treatment in certain research approaches.</p>Formula:C6H6N6O2Purezza:Min. 98 Area-%Colore e forma:Off-White PowderPeso molecolare:194.15 g/molTemozolomide - Bio-X ™
CAS:<p>Temozolomide is an imidazotetrazine alkylating agent. It has anti-tumor activity against a broad spectrum of tumors, such as leukemias, lymphomas and solid tumors. Temozolomide induces G2/M arrest, preventing cells from entering mitosis and, therefore, apoptosis. As a drug resistance-modifying agent it is used for studying drug resistance mechanisms in glioblastoma cell lines.</p>Formula:C6H6N6O2Purezza:Min. 98 Area-%Colore e forma:White To Pale Pink SolidPeso molecolare:194.15 g/mol
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