CAS 856866-72-3

tedizolide

Descrizione:

tedizolide è un antibiotico oxazolidinone che viene utilizzato principalmente per il trattamento di infezioni batteriche acute della pelle e delle strutture cutanee. Presenta un meccanismo d'azione simile a quello della linezolid, inibendo la sintesi proteica batterica legandosi alla subunità ribosomiale 50S. tedizolide è efficace contro una gamma di batteri Gram-positivi, inclusi Staphylococcus aureus resistente alla meticillina (MRSA). Una delle sue caratteristiche notevoli è la sua potenza migliorata e il profilo farmacocinetico, che consente una somministrazione una volta al giorno. tedizolide è anche caratterizzato da un profilo di sicurezza favorevole, con una minore incidenza di alcuni effetti collaterali rispetto agli antibiotici più vecchi della sua classe. Viene somministrato per via orale o endovenosa ed è generalmente ben tollerato. La struttura chimica di tedizolide include un anello di oxazolidinone sostituito, contribuendo alla sua attività antibatterica. Come con qualsiasi antibiotico, l'emergere di resistenza è una preoccupazione, richiedendo un uso attento e l'adesione alle linee guida prescritte.

Formula: C₁₇H₁₅FN₆O₃

InChI: InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1

InChI key: InChIKey=XFALPSLJIHVRKE-GFCCVEGCSA-N

SMILES: O=C1N(C[C@H](CO)O1)C2=CC(F)=C(C=C2)C=3C=CC(=NC3)C4=NN(C)N=N4

Sinonimi:

• (5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
• (5R)-3-[3-Fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one
• (R)-3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
• 2-Oxazolidinone, 3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-, (5R)-
• 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
• Da 7157
• Sivextro
• Tedizolid Intermediate-8
• Torezolid
• Tr 700
• (5R)-3-{3-fluoro-4-[6-(2-Methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-5-(hydroxyMethyl)-1,3-oxazolidin-2-one Phosphate
• Tedizolid (TR-701)
• 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone Torezolid (TR-701
• (R)-3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolid
• Specially acetazolaMide
• Tedizolid Impurity7
• Torezolid (TR-701
• Tedizolid free base
• -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one
• 3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
• Tedizolid
• 3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidi
• (5R)-3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-Oxazolidin
• (R)-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one

Torezolid

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 370.3378

Ref: IN-DA00G3Q0

Tedizolid

CAS: 856866-72-3

Tedizolid

Purezza: ≥95%

Peso molecolare: 370.34g/mol

Ref: 54-BUP09375

(R)-3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-Yl)Pyridin-3-Yl)Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One

CAS: 856866-72-3

(R)-3-(3-Fluoro-4-(6-(2-Methyl-2H-Tetrazol-5-Yl)Pyridin-3-Yl)Phenyl)-5-(Hydroxymethyl)Oxazolidin-2-One

Purezza: 98%

Peso molecolare: 370.34g/mol

Ref: 54-PC109186

Torezolid

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Purezza: (HPLC) ≥ 98.0%

Colore e forma: White to off-white or beige powder

Peso molecolare: 370.34

Ref: 7W-GA5035

Tedizolid-13C-d3

CAS: 856866-72-3

Formula: C₁₆₁₃CH₁₂D₃FN₆O₃

Colore e forma: White To Off-White Solid

Peso molecolare: 374.36

Ref: 4Z-T-163056

Tedizolid

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Colore e forma: Off-White Solid

Peso molecolare: 370.34

Ref: 4Z-T-163001

Tedizolid

CAS: 856866-72-3

Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of

Formula: C₁₇H₁₅FN₆O₃

Purezza: 96.97% - 99.89%

Colore e forma: Solid

Peso molecolare: 370.34

Ref: TM-T1747

Tedizolid

CAS: 856866-72-3

Applications Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.
References Schaadt, R. et al.: Antimicrob. Agents Chemother., 53, 3236 (2009); Lemaire, S. et al.: J. Antimicrob. Chemother., 64, 1035 (2009)

Formula: C₁₇H₁₅FN₆O₃

Colore e forma: Neat

Peso molecolare: 370.34

Ref: TR-T013750

Torezolid

CAS: 856866-72-3

Torezolid (Tedizolid) is an oxazolidinone antibiotic with action on bacterial protein synthesis by binding to the 50S ribosomal subunit and is used for treating acute bacterial skin and skin structure infections.

Formula: C₁₇H₁₅FN₆O₃

Purezza: Min. 95.0 Area-%

Colore e forma: Powder

Peso molecolare: 370.34 g/mol

Ref: 3D-FT35374

TEDIZOLID

CAS: 856866-72-3

Formula: C₁₇H₁₅FN₆O₃

Purezza: 98%

Peso molecolare: 370.344

Ref: 10-F466765

Tedizolid-(d1,d2,d3) Deuterium Mixture

Prodotto controllato

CAS: 856866-72-3

Applications Tedizolid-d3, is the labelled form of Tedizolid, known as TR-700, is an oral and i.v administered intracellular antibacterial drug.
References Schaadt, R. et al.: Antimicrob. Agents Chemother., 53, 3236 (2009); Lemaire, S. et al.: J. Antimicrob. Chemother., 64, 1035 (2009)

Formula: C₁₇₂H₃H₁₂FN₆O₃

Colore e forma: Neat

Peso molecolare: 373.36

Ref: TR-T013752