
CAS 858-98-0
:Ref: 4Z-E-100011
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CAS:Prodotto controllatoApplications Protected Estrone
References Berube, G., et al.: Steroids, 71, 911 (2006), Allan, G., et al.: J. Med. Chem., 49, 1325 (2006), Woo, L., et al.: Mol. Cancer Ther., 7, 2435 (2008),Formula:C25H28O2Colore e forma:NeatPeso molecolare:360.493-O-Benzyl estrone
CAS:Prodotto controllato3-O-Benzyl estrone is a boron trifluoride etherate that has been investigated as a radiolabeled estrogen receptor alpha agonist. 3-O-Benzyl estrone has been shown to be an effective cancer therapy in the treatment of breast, colon, and skin cancers. It also has anti-inflammatory properties by inhibiting cytokine production. The chemical structure of 3-O-Benzyl estrone is an estradiol amide with a benzene ring in the ortho position. The heterocycle is substituted with three fluorines at the 3, 4, and 5 positions. This estrogenic agent is prepared via the reduction of borohydride with hydrogen gas. 3-O-Benzyl estrone binds to the estrogen receptor alpha and inhibits protein synthesis by binding to DNA at specific sites on the gene promoter region.
Formula:C25H28O2Purezza:Min. 95%Peso molecolare:360.49 g/molRef: ST-EA-CP-E30034
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