CAS 86060-81-3

S-[(Acetilammino)metil]-N-[(9H-fluoren-9-ilmetossi)carbonil]-L-cisteina

Descrizione:

S-[(Acetilammino)metil]-N-[(9H-fluoren-9-ilmetossi)carbonil]-L-cisteina, con il numero CAS 86060-81-3, è un derivato sintetico di amminoacidi che presenta uno scheletro di cisteina modificato con un gruppo acetilamminico e un gruppo protettivo di fluorenilmetossicarbonile (Fmoc). Questo composto è caratterizzato dalla sua capacità di partecipare alla sintesi di peptidi, in particolare nella formazione di legami peptidici grazie alla presenza dei gruppi funzionali amminico e carbossilico propri degli amminoacidi. Il gruppo Fmoc funge da moiety protettivo, consentendo una deprotezione selettiva durante la sintesi di peptidi, che è cruciale nella sintesi di peptidi in fase solida. La modifica acetilamminica migliora la solubilità e la stabilità del composto, rendendolo adatto per varie applicazioni biochimiche. Inoltre, la presenza dell'atomo di zolfo nel residuo di cisteina consente potenziali reazioni redox e la formazione di legami disolfuro, che sono importanti nella struttura e funzione delle proteine. In generale, questo composto è prezioso nel campo della chimica medicinale e della ricerca sui peptidi.

Formula: C₂₁H₂₂N₂O₅S

InChI: InChI=1S/C21H22N2O5S/c1-13(24)22-12-29-11-19(20(25)26)23-21(27)28-10-18-16-8-4-2-6-14(16)15-7-3-5-9-17(15)18/h2-9,18-19H,10-12H2,1H3,(H,22,24)(H,23,27)(H,25,26)/t19-/m0/s1

InChI key: InChIKey=CSMYOORPUGPKAP-IBGZPJMESA-N

SMILES: C(OC(N[C@@H](CSCNC(C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2R)-3-(Acetamidomethylsulfanyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• (2R)-3-[(Acetamidomethyl)sulfanyl]-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
• <span class="text-smallcaps">L</span>-Cysteine, S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-Cys(Acm)-OH
• Fmoc-L-Cys(Acm)-OH
• Fmoc-L-Cysteine(Acm)
• Fmoc-S-(acetamidomethyl)-L-cysteine
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(acetamidomethyl)-<span class="text-smallcaps">L</span>-cysteine
• N-fmoc-S-acetamidomethyl L-cysteine
• S-[(Acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-cysteine
• S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-cysteine
• S-[(acetylamino)methyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cysteine
• N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(acetamidomethyl)-L-cysteine

N-Fmoc-S-acetamidomethyl-L-cysteine, 95%

CAS: 86060-81-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₁H₂₂N₂O₅S

Purezza: 95%

Peso molecolare: 414.48

Ref: 02-H59306

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Following Fmoc-SPPS, Acm can be converted on resin into the S-carbomethoxysulfenyl (Scm) group. Scm is cleaved by reduction with DTT, treatment with thiols yields unsymmetrical disulfides.

Formula: C₂₁H₂₂N₂O₅S

Purezza: 99.5%

Colore e forma: White

Peso molecolare: 414.48

Ref: 01-4006622

Fmoc-L-Cys(Acm)-OH

CAS: 86060-81-3

Formula: C₂₁H₂₂N₂O₅S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 414.4748

Ref: IN-DA0036F0

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Formula: C₂₁H₂₂N₂O₅S

Peso molecolare: 414.47

Ref: 7W-GM1615

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Fmoc-Cys(Acm)-OH

Purezza: 98%

Peso molecolare: 414.47g/mol

Ref: 54-OR1013335

Fmoc-Cys(Acm)-OH, 10mM (in DMSO)

CAS: 86060-81-3

Fmoc-Cys(Acm)-OH, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 414.47g/mol

Ref: 54-BUP19108

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Fmoc-Cys(Acm)-OH (Fmoc-S-acetamidomethyl-L-cysteine) is a cysteine derivative.

Formula: C₂₁H₂₂N₂O₅S

Purezza: 99.89%

Colore e forma: Solid

Peso molecolare: 414.47

Ref: TM-T64327

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

Formula: C₂₁H₂₂N₂O₅S

Purezza: >95.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 414.48

Ref: 3B-A3534

Cysteine Impurity 12 (Fmoc-Cys(Acm)-OH)

CAS: 86060-81-3

Formula: C₂₁H₂₂N₂O₅S

Peso molecolare: 414.48

Ref: 4Z-C-77125

Fmoc-Cys(Acm)-OH

CAS: 86060-81-3

M03396 - Fmoc-Cys(Acm)-OH

Formula: C₂₁H₂₂N₂O₅S

Purezza: 97%

Colore e forma: Beige powder

Peso molecolare: 414.48

Ref: 10-M03396

Fmoc-S-acetamidomethyl-L-cysteine

CAS: 86060-81-3

Fmoc-S-acetamidomethyl-L-cysteine is a peptide analog that has been shown to inhibit the growth of HIV in human prostate cells. It binds to the du-145 cell receptor and inhibits the proteolytic activity of HIV, which may be due to its ability to form an amide bond or disulfide bond with the Cys residue (Cys-X). Fmoc-S-acetamidomethyl-L-cysteine also inhibits the growth of prostate cancer cells by binding to human serum albumin. This drug has minimal toxicity in fetal bovine serum and is not toxic to most bacteria, as it does not bind with glycopeptides, antimicrobial peptides, or proteins. Fmoc-S-acetamidomethyl-L-cysteine has been shown to have biological properties against Trichophyton mentagrophytes and Staphylococcus a

Formula: C₂₁H₂₂N₂O₅S

Purezza: (Chiral Hplc) Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 414.48 g/mol

Ref: 3D-FF47336

FMOC-S-Acetamido Methyl-L-Cysteine (Fmoc-Cys(Acm)-OH) extrapure, 98%

CAS: 86060-81-3

Formula: C₂₁H₂₂N₂O₅S

Purezza: min. 98.0%

Colore e forma: White to Slight yellow to Beige, Powder, Clear

Peso molecolare: 414.48

Ref: SR-97306