CAS 862772-11-0

Cyclo(-Arg-Gly-Asp-D-Phe-Cys)

CAS: 862772-11-0

c(RGDfC), a RGD tumor-targeting peptide, which binds to αvβ3 receptors. c(RGDfC) can be easily conjugated to drugs as combretastatin or surfaces.

Formula: C₂₄H₃₄N₈O₇S

Purezza: 95.6%

Colore e forma: White

Peso molecolare: 578.65

Ref: 01-4069272

2-[(2R,5R,8R,11S)-5-Benzyl-11-(3-carbamimidamidopropyl)-3,6,9,12,15-pentaoxo-8-(sulfanylmethyl)-1,4,7,10,13-pentaazacyclopentadecan-2-yl]acetic acid

CAS: 862772-11-0

Formula: C₂₄H₃₄N₈O₇S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 578.6412

Ref: IN-DA00GV4S

2-((2S,5R,8R,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-(mercaptomethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid

CAS: 862772-11-0

2-((2S,5R,8R,11S)-5-Benzyl-11-(3-guanidinopropyl)-8-(mercaptomethyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid

Purezza: 98%

Peso molecolare: 578.65g/mol

Ref: 54-OR1073933

Cyclo(Arg-Gly-Asp-D-Phe-Cys)

CAS: 862772-11-0

Cyclo(Arg-Gly-Asp-D-Phe-Cys) is a cyclic peptide that can form stable complexes with platinum. It has been shown to have anticancer activity against cervical cancer cells in tissue culture. Cyclo(Arg-Gly-Asp-D-Phe-Cys) binds to the integrin receptor on the surface of cancer cells, which leads to changes in redox potential, leading to cell death by apoptosis or necrosis. Cyclo(Arg-Gly-Asp-D-Phe-Cys) also has pharmacological properties that make it a good candidate for treatment of cancer.

Formula: C₂₄H₃₄N₈O₇S

Purezza: Min. 95%

Peso molecolare: 578.65 g/mol

Ref: 3D-PCI-3686-PI

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt

CAS: 862772-11-0

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt is a peptide that has been modified to be an active targeting agent. It is an amphipathic molecule that can be used to deliver therapeutic agents specifically to cancer cells. Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt is conjugated to a drug and is taken up by cells through the process of endocytosis. Once inside the cell, the drug is released and binds with the cell membrane, which leads to cell death. The uptake of this peptide has been shown to be pH dependent; it is taken up more readily in acidic environments than in neutral or alkaline environments. This peptide has also been shown to have cytotoxic effects on both MFC7 cells and rat liver cells.

Formula: C₂₄H₃₄N₈O₇S

Purezza: Min. 95%

Peso molecolare: 578.64 g/mol

Ref: 3D-FC110008