CAS 86386-73-4

Fluconazolo

Descrizione:

Fluconazolo è un farmaco antifungino utilizzato principalmente per trattare le infezioni fungine, in particolare quelle causate da specie di Candida e Cryptococcus neoformans. Appartiene alla classe degli antifungini triazolici e agisce inibendo la sintesi dell'ergosterolo, un componente essenziale delle membrane cellulari fungine, compromettendo così la loro integrità e funzione. Fluconazolo è caratterizzato dalla sua alta biodisponibilità orale, che consente un trattamento sistemico efficace, ed è spesso somministrato sia per via orale che endovenosa. La sostanza è generalmente ben tollerata, con effetti collaterali comuni che includono disturbi gastrointestinali e mal di testa. Ha una emivita relativamente lunga, che consente una somministrazione una volta al giorno per molte indicazioni. Fluconazolo è anche notevole per la sua capacità di penetrare in vari tessuti del corpo, incluso il sistema nervoso centrale, rendendolo efficace nel trattamento della meningite. Tuttavia, può interagire con altri farmaci a causa dei suoi effetti sugli enzimi epatici, richiedendo un attento monitoraggio nei pazienti in terapia multipla. In generale, Fluconazolo è un agente critico nella gestione delle infezioni fungine sistemiche e superficiali.

Formula: C₁₃H₁₂F₂N₆O

InChI: InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

InChI key: InChIKey=RFHAOTPXVQNOHP-UHFFFAOYSA-N

SMILES: C(CN1C=NC=N1)(CN2C=NC=N2)(O)C3=C(F)C=C(F)C=C3

Sinonimi:

• 1-(2,4-Difluorophenyl)-1,1-bis[(1H-1,2,4-triazol-1-yl)methyl]methanol
• 1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-
• 2-(2,4-Difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol
• 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
• Alkanazole
• Biozolene
• Diflucan
• Difluconazole
• Elazor
• Floroxan
• Flucan
• Fluconal
• Flucostat
• Flumycon
• Flunazol
• Flusol
• Flutec
• Fluzon
• Fungican
• Fungicon
• Triconal
• Triflucan
• Uk 49858
• Zocon
• Zoltec
• a.-(2,4-Difluorophenyl)-a-(1H-1,2,4,-triazol-1-ylmethyl)-1H-1,2 ,4-triazole-1-ethanol
• α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol

Fluconazole

CAS: 86386-73-4

Formula: C₁₃H₁₂F₂N₆O

Purezza: >98.0%(GC)(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 306.28

Ref: 3B-F0677

Fluconazole, 99%

CAS: 86386-73-4

Fluconazole, 86386-73-4, is a synthetic triazole, demethylase, and a cytochrome P-450 inhibitor with antifungal activity against some Candida infections. Learn more.

Formula: C₁₃H₁₂F₂N₆O

Purezza: 99%

Colore e forma: White to pale cream, Powder

Peso molecolare: 306.28

Ref: 02-J62015

Fluconazole 2.0 mg/ml in Methanol

CAS: 86386-73-4

Colore e forma: Single Solution

Ref: 61-AMP0235.00-07

Fluconazole

CAS: 86386-73-4

Fluconazole

Formula: C₁₃H₁₂F₂N₆O

Purezza: 99.4%

Colore e forma: White. To. Off-White

Peso molecolare: 306.10407

Ref: 47-1174

FLUCONAZOLE CRS

CAS: 86386-73-4

FLUCONAZOLE CRS

Formula: C₁₃H₁₂F₂N₆O

Colore e forma: Crystalline Powder. White. Powder.

Peso molecolare: 306.2708

Ref: 41-Y0000557

FLUCONAZOLE FOR PEAK IDENTIFICATION CRS

CAS: 86386-73-4

FLUCONAZOLE FOR PEAK IDENTIFICATION CRS

Formula: C₁₃H₁₂F₂N₆O

Peso molecolare: 306.2708

Ref: 41-Y0000558

Fluconazole impurity standard

CAS: 514222-44-7, 86386-73-4, 871550-15-1, 89429-59-4

Fluconazole impurity standard

Colore e forma: White

Ref: 47-1175

Fluconazole

CAS: 86386-73-4

Anti-infective agents, nesoi

Formula: C₁₃H₁₂F₂N₆O

Colore e forma: White Off-White Powder

Peso molecolare: 306.10407

Ref: 45-1271700

1H-1,2,4-Triazole-1-ethanol, α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-

CAS: 86386-73-4

Formula: C₁₃H₁₂F₂N₆O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 306.2708

Ref: IN-DA000KX6

Fluconazole

CAS: 86386-73-4

Fluconazole (UK-49858) is a triazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS.

Formula: C₁₃H₁₂F₂N₆O

Purezza: 98.57% - 99.17%

Colore e forma: White Or Off White Crystalline Powder

Peso molecolare: 306.27

Ref: TM-T1388

Fluconazole

CAS: 86386-73-4

Fluconazole

Purezza: ≥95%

Peso molecolare: 306.27g/mol

Ref: 54-BUP15117

Fluconazole

CAS: 86386-73-4

Formula: C₁₃H₁₂F₂N₆O

Purezza: (non-aqueous titration) ≥ 98.5% (dried basis)

Colore e forma: White to almost white powder or crystals

Peso molecolare: 306.27

Ref: 7W-GA4147

Fluconazole (anhydrous)

CAS: 86386-73-4

Fluconazole (anhydrous)

Formula: C₁₃H₁₂F₂N₆O

Purezza: 98%

Colore e forma: white solid

Peso molecolare: 306.27078g/mol

Ref: 54-BI3858

Fluconazole

CAS: 86386-73-4

Formula: C₁₃H₁₂F₂N₆O

Colore e forma: White To Off-White Solid

Peso molecolare: 306.28

Ref: 4Z-F-142

Fluconazole-d4 (bismethylene-d4) (

CAS: 1124197-58-5, 86386-73-4

Purezza: 98 atom % D

Colore e forma: White To Off-White Solid

Peso molecolare: 310.30

Ref: 3U-D6143

Fluconazole

CAS: 86386-73-4

Colore e forma: Neat

Ref: 86-MM0235.00

Fluconazole 100 µg/mL in Acetonitrile

CAS: 86386-73-4

Formula: C₁₃H₁₂F₂N₆O

Colore e forma: Single Solution

Peso molecolare: 306.27

Ref: 04-A13697500AL-100

Fluconazole

Prodotto controllato

CAS: 86386-73-4

Formula: C₁₃H₁₂F₂N₆O

Colore e forma: Neat

Peso molecolare: 306.27

Ref: 04-C13697500

Fluconazole

CAS: 86386-73-4

Applications Fluconazole is used as an antifungal.
References Richard, K. et al.: Antimicrob. Ag. Chemother., 27, 832 (1985),

Formula: C₁₃H₁₂F₂N₆O

Colore e forma: Neat

Peso molecolare: 306.27

Ref: TR-F421000

Fluconazole - Bio-X ™

CAS: 86386-73-4

Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).

Formula: C₁₃H₁₂F₂N₆O

Purezza: (%) Min. 95%

Colore e forma: Powder

Peso molecolare: 306.27 g/mol

Ref: 3D-BF164466