CAS 864821-90-9

5-[[[(2S)-2-Amino-3-[4-(aminocarbonil)-2,6-dimetilfenil]-1-ossopropil][(1S)-1-(5-fenil-1H-imidazol-2-il)etil]amino]metil]-2-metossibenzoico acido

Descrizione:

La sostanza chimica con il nome "5-[[[(2S)-2-Amino-3-[4-(aminocarbonil)-2,6-dimetilfenil]-1-ossopropil][(1S)-1-(5-fenil-1H-imidazol-2-il)etil]amino]metil]-2-metossibenzoico acido" e numero CAS "864821-90-9" è un composto organico complesso caratterizzato dalla sua struttura intricata, che include più gruppi funzionali come amino, carbonile e metossile. Questo composto probabilmente mostrerà proprietà tipiche degli amminoacidi e dei derivati correlati, inclusa la potenziale solubilità in solventi polari grazie alla presenza di funzionalità amminiche e acidi carbossilici. La sua struttura suggerisce che potrebbe avere attività biologica, possibilmente come agente farmaceutico, data la presenza di gruppi imidazolo e fenile, spesso associati a proprietà simili a quelle dei farmaci. Il peso molecolare, la stabilità e la reattività del composto dipenderebbero dal suo specifico arrangiamento di atomi e gruppi funzionali, influenzando le sue interazioni nei sistemi biologici e le sue potenziali applicazioni in chimica medicinale. Ulteriori studi sarebbero necessari per chiarire le sue caratteristiche precise e gli effetti biologici.

Formula: C₃₂H₃₅N₅O₅

InChI: InChI=1S/C32H35N5O5/c1-18-12-23(29(34)38)13-19(2)24(18)15-26(33)31(39)37(17-21-10-11-28(42-4)25(14-21)32(40)41)20(3)30-35-16-27(36-30)22-8-6-5-7-9-22/h5-14,16,20,26H,15,17,33H2,1-4H3,(H2,34,38)(H,35,36)(H,40,41)/t20-,26-/m0/s1

InChI key: InChIKey=QFNHIDANIVGXPE-FNZWTVRRSA-N

SMILES: N([C@@H](C)C=1NC(=CN1)C2=CC=CC=C2)(CC3=CC(C(O)=O)=C(OC)C=C3)C([C@H](CC4=C(C)C=C(C(N)=O)C=C4C)N)=O

Sinonimi:

• Eluxadoline
• 5-[[[(2S)-2-Amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(5-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxybenzoic acid
• Benzoic acid, 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxy-
• JNJ 27018966
• Benzoic acid, 5-[[[(2S)-2-amino-3-[4-(aminocarbonyl)-2,6-dimethylphenyl]-1-oxopropyl][(1S)-1-(5-phenyl-1H-imidazol-2-yl)ethyl]amino]methyl]-2-methoxy-

Eluxadoline

CAS: 864821-90-9

Formula: C₃₂H₃₅N₅O₅

Peso molecolare: 569.66

Ref: 4Z-E-087001

Eluxadoline-13C-d3

CAS: 864821-90-9

Formula: C₃₂H₃₂N₅O₅D₃

Peso molecolare: 573.67

Ref: 4Z-E-087003

Eluxadoline

Prodotto controllato

CAS: 864821-90-9

Formula: C₃₂H₃₅N₅O₅

Colore e forma: Off-White

Peso molecolare: 569.65

Ref: TR-E508195

Eluxadoline-glucuronide

Prodotto controllato

CAS: 864821-90-9

Eluxadoline-glucuronide is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide modification. It has a CAS No., which is 637259-71-2. Eluxadoline-glucuronide is an oligosaccharide with glycosylation and sugar composition. The carbohydrate complex is composed of saccharides and polysaccharides. This product can be used in the production of pharmaceuticals, agrochemicals, or other chemical substances.

Purezza: Min. 95%

Ref: 3D-ME146113

Eluxadoline-13C,d3 Dihydrochloride

Prodotto controllato

CAS: 864821-90-9, 864825-13-8

Applications Eluxadoline-13C,d3 Dihydrochloride is labelled Eluxadoline Dihydrochloride (E508200) which is a mixed μ opioid receptor agonist / δ opioid receptor antagonist used in the treatment and modulation of gastrointestinal function. Used in patients with diarrhea-predominant IBS.
References Wade, P. et al.: Brit. J. Pharm., 167, 1111 (2012); Breslin, H. et al.: Bioorg. Med. Chem. Lett., 22, 4869 (2012)

Formula: C₃₁CH₃₄D₃Cl₂N₅O₅

Colore e forma: Neat

Peso molecolare: 573.662

Ref: TR-E508203

Eluxadoline deuterated

Prodotto controllato

CAS: 864821-90-9

Eluxadoline is a drug that has been developed to treat the symptoms of irritable bowel syndrome with constipation. This medicine is a selective agonist at opioid receptors, which are found in the bowel and the central nervous system. Eluxadoline has demonstrated efficacy in patients with inflammatory bowel diseases, including ulcerative colitis, Crohn's disease, and pouchitis. The drug is not metabolized by cytochrome P450 enzymes and does not inhibit or induce these enzymes. It also does not bind to serum proteins such as albumin or α1-acid glycoprotein. Side effects can include nausea, dizziness, headache, and diarrhea.

Formula: C₃₂H₃₅N₅O₅

Purezza: Min. 95%

Peso molecolare: 569.65 g/mol

Ref: 3D-FE146108