CAS 866914-87-6

ARL-17477 dihydrochloride hydrate

CAS: 866914-87-6

Formula: C₂₀H₂₀ClN₃S·2HCl·xH₂O

Peso molecolare: 442.83 (anhydrous)

Ref: 7W-GL6359

ARL 17477 Dihydrochloride

Prodotto controllato

CAS: 866914-87-6

ARL 17477 is a potent and selective pharmacological inhibitor of guanylate cyclase (GC) that was developed for use in animal research. It inhibits the production of pro-inflammatory cytokines and has been shown to decrease the incidence of spontaneous tumors in animals. ARL 17477 inhibits GC by binding reversibly to the enzyme's active site, preventing the conversion of GTP to cGMP, which is required for cell proliferation. ARL 17477 also inhibits magnesium-dependent polymerase chain reaction (PCR), leading to decreased levels of DNA synthesis, cell proliferation, and tissue staining.

Formula: C₂₀H₂₀ClN₃S•(HCl)₂

Purezza: Min. 95%

Peso molecolare: 369.91 g/mol

Ref: 3D-RJB91487