CAS 87096-84-2

neuromedina B

Descrizione:

neuromedina B è un neuropeptide che svolge un ruolo significativo in vari processi fisiologici, inclusa la regolazione della contrazione del muscolo liscio e la modulazione delle funzioni neuroendocrine. È composto da una sequenza di amminoacidi ed è classificato come un membro della famiglia delle neuromedine, che sono coinvolte nella neurotrasmissione e nella segnalazione all'interno del sistema nervoso centrale. neuromedina B agisce principalmente attraverso recettori specifici, influenzando processi come la regolazione dell'appetito, la risposta allo stress e le funzioni riproduttive. Si sa che il peptide è coinvolto nella fisiopatologia di alcune condizioni, tra cui obesità e disturbi d'ansia. La sua struttura include tipicamente un'amidazione C-terminale, che è cruciale per la sua attività biologica. neuromedina B è sintetizzato in vari tessuti, inclusi il cervello e il tratto gastrointestinale, e i suoi effetti sono mediati attraverso interazioni con recettori accoppiati a proteine G. La ricerca continua a esplorare le sue potenziali applicazioni terapeutiche, in particolare nel contesto di disturbi metabolici e neuropsichiatrici.

Formula: C₅₂H₇₃N₁₅O₁₂S

InChI: InChI=1/C52H73N15O12S/c1-27(2)17-36(64-51(78)40(21-41(54)69)61-42(70)22-53)48(75)66-38(19-31-23-57-34-14-10-9-13-33(31)34)47(74)60-28(3)46(73)67-44(29(4)68)52(79)58-25-43(71)62-39(20-32-24-56-26-59-32)50(77)65-37(18-30-11-7-6-8-12-30)49(76)63-35(45(55)72)15-16-80-5/h6-14,23-24,26-29,35-40,44,57,68H,15-22,25,53H2,1-5H3,(H2,54,69)(H2,55,72)(H,56,59)(H,58,79)(H,60,74)(H,61,70)(H,62,71)(H,63,76)(H,64,78)(H,65,77)(H,66,75)(H,67,73)/t28-,29+,35-,36-,37?,38-,39-,40-,44-/m0/s1

Sinonimi:

• H-Gly-Asn-Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2
• (2S)-2-[(2-aminoacetyl)amino]-N-[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S,2R)-1-[[2-[[(1S)-2-[[1-benzyl-2-[[(1S)-1-carbamoyl-3-methylsulfanyl-propyl]amino]-2-oxo-ethyl]amino]-1-(3H-imidazol-4-ylmethyl)-2-oxo-ethyl]amino]-2-oxo-ethyl]carbamoyl]-2-hydroxy-propyl]amino]-1-methyl-2-oxo-ethyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]butanediamide

Neuromedin B

CAS: 87096-84-2

For cellular and molecular biology applications

Formula: C₅₂H₇₃N₁₅O₁₂S

Colore e forma: Lyophilized powder

Peso molecolare: 1132.3

Ref: 02-J66286

Neuromedin B

CAS: 87096-84-2

NMB, a bombesin-linke peptide, binds to the bombesin receptors BRS1-4. NMB is expressed in the pituitary, brain, pancreas, adrenal and gastrointestinal tract. Its expression in adipose tissue appears to be regulated by changes in energy balance. NMB could inhibit food intake and modulates stress-related behavior.

Formula: C₅₂H₇₃N₁₅O₁₂S

Purezza: 97.4%

Colore e forma: White Powder

Peso molecolare: 1132.31

Ref: 01-4020211

Neuromedin B

CAS: 87096-84-2

Neuromedin B

Purezza: ≥98%

Peso molecolare: 1132.29g/mol

Ref: 54-BUP01758

Neuromedin B

CAS: 87096-84-2

Neuromedin B, a mammalian peptide related to bombesin, is found in the CNS and GI tract, originally purified from pig spinal cords.

Formula: C₅₂H₇₃N₁₅O₁₂S

Purezza: 99.39%

Colore e forma: Solid

Peso molecolare: 1132.29

Ref: TM-TP1442

Neuromedin B (porcine)

CAS: 87096-84-2

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₅₂H₇₃N₁₅O₁₂S

Peso molecolare: 1,132.3 g/mol

Ref: 3D-PP50044

Neuromedin C (Human, Porcine, Canine)

CAS: 87096-84-2

Neuromedin C (NMC) is a peptide that belongs to the family of neuromedin and is a potent activator of ion channels. It has been shown to be a ligand for opioid receptors, which may be due to its ability to inhibit the release of neurotransmitters such as acetylcholine and noradrenaline. Neuromedin C has also been shown to inhibit the binding of morphine-6 beta-glucuronide in rat brain synaptosomes. In addition, NMC has been reported as an inhibitor of cell proliferation and induce apoptosis in various cancer cells including colon and prostate cancers.

Formula: C₅₀H₇₃N₁₇O₁₁S

Purezza: Min. 95%

Peso molecolare: 1,120.3 g/mol

Ref: 3D-PNM-4153-V

Neuromedin B (Human, Porcine, Rat)

CAS: 87096-84-2

Neuromedin B is a neuropeptide that has been shown to activate the TRPC ion channels in mammalian cells. It also has been shown to bind to receptors and have a potent effect on cell biology, as well as being used as a research tool for studying protein interactions. Neuromedin B is found in humans, pigs, and rats, where it is expressed primarily in the brain and gastrointestinal tract. This peptide has been shown to be an inhibitor of some types of ion channels.

Formula: C₅₂H₇₃N₁₅O₁₂S

Purezza: Min. 95%

Peso molecolare: 1,132.3 g/mol

Ref: 3D-PNM-4152-V

Neuromedin B trifluoroacetate salt

CAS: 87096-84-2

Neuromedin B is a peptide hormone that is produced by the hypothalamus and regulates many physiological processes such as energy metabolism, appetite, and sleep. Neuromedin B is a member of the family of guanine nucleotide-binding proteins (G proteins) that bind to G protein-coupled receptors on the surface of cells. It has been shown to stimulate calcium release from intracellular stores in response to an increase in cytosolic Ca2+. Neuromedin B has been shown to have anti-inflammatory effects on infectious diseases such as meningitis, sepsis, and tuberculosis, which may be due to its ability to inhibit neutrophil migration. Neuromedin B also stimulates hippocampal formation activity in rats during the rotarod test, which may be due to its effects on dopamine release.

Formula: C₅₂H₇₃N₁₅O₁₂S

Purezza: Min. 95%

Peso molecolare: 1,132.3 g/mol

Ref: 3D-FN108954