CAS 87239-81-4

Cefpodoxima proxetile

Descrizione:

Cefpodoxima proxetile è un antibiotico cefalosporinico ad ampio spettro utilizzato principalmente per trattare infezioni batteriche. È un pro-farmaco, il che significa che viene convertito nella sua forma attiva, cefpodoxime, dopo la somministrazione. Questo composto presenta un alto grado di stabilità contro varie beta-lattamasi, che sono enzimi prodotti da alcuni batteri per resistere all'azione degli antibiotici. Cefpodoxima proxetile è efficace contro una gamma di batteri Gram-positivi e Gram-negativi, rendendolo adatto per trattare infezioni delle vie respiratorie, infezioni del tratto urinario e infezioni cutanee. La sostanza viene tipicamente somministrata per via orale ed è ben assorbita nel tratto gastrointestinale, con la sua biodisponibilità migliorata dalla presenza di cibo. Il suo meccanismo d'azione implica l'inibizione della sintesi della parete cellulare batterica, portando alla lisi cellulare e alla morte. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, reazioni allergiche e, in rari casi, superinfezione a causa dell'interruzione della flora normale. Come con tutti gli antibiotici, è fondamentale usare Cefpodoxima proxetile in modo giudizioso per minimizzare lo sviluppo di resistenza agli antibiotici.

Formula: C₁₅H₁₇N₅O₆S₂

InChI: InChI=1/C21H27N5O9S2/c1-9(2)33-21(30)35-10(3)34-19(29)15-11(6-31-4)7-36-18-14(17(28)26(15)18)24-16(27)13(25-32-5)12-8-37-20(22)23-12/h8-10,14,18H,6-7H2,1-5H3,(H2,22,23)(H,24,27)/b25-13-/t10?,14-,18-/m1/s1

InChI key: InChIKey=LTINZAODLRIQIX-FBXRGJNPSA-N

SMILES: C(OC(OC(OC(C)C)=O)C)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1COC)[H]

Sinonimi:

• (Rs)-1(Isopropoxycarbonyloxy)Ethyl (+)-(6R,7R)-7-[2-(2-Amino-4-Thiazolyl)-2-[(Z)Methoxyimino]Acetamido]-3-Methoxymethyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylate
• 1-{[(1-methylethoxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 1-{[(1-methylethoxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 1-{[(1-methylethoxy)carbonyl]oxy}ethyl 7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-
• Antibiotic CS 807
• Banan
• CS 807 (pharmaceutical)
• Cefodox
• Cefoflam
• Cefoprox
• Cefpodoxime
• Cephpodoxime proxetil
• Cepodem
• Cs 807
• Orelox
• Otreon
• Ru 51807
• Simplicef
• U 76252
• Vantin
• CEFPODOXIME PROXETIL
• 1-(((1-methylethoxy)car
• (+)-(6R,7R)-7-[2-(2-AMINO-4-THIAZOLYL)-2-[(Z)METHOXYIMINO]ACETAMIDO]-3-METHOXYMETHYL-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLATE
• CefpodoximeProxet
• Cefpodoxime Proxetil JPFa
• CS-807, U-76252, Banan, Cefodox, Orelox, Otreon, Vantin
• JP,USP
• R-3763
• (6r-(6-alpha,7-beta(z)))-bonyl)oxy)ethyleste
• Cefopodoximeproxetil

Glutaraldehyde, 25% aq. soln.

CAS: 87239-81-4

A broad spectrum antibiotic

Formula: C₂₁H₂₇N₅O₉S₂

Purezza: 96%

Colore e forma: Powder

Peso molecolare: 557.59

Ref: 02-J66061

CEFPODOXIME PROXETIL CRS

CAS: 87239-81-4

CEFPODOXIME PROXETIL CRS

Ref: 41-Y0001305

CEFPODOXIME PROXETIL FOR PEAK IDENTIFICATION CRS

CAS: 87239-81-4

CEFPODOXIME PROXETIL FOR PEAK IDENTIFICATION CRS

Formula: C₂₁H₂₇N₅O₉S₂

Peso molecolare: 557.5972

Ref: 41-Y0001306

CEFPODOXIME PROXETIL FOR IMPURITY H IDENTIFICATION CRS

CAS: 87239-81-4

CEFPODOXIME PROXETIL FOR IMPURITY H IDENTIFICATION CRS

Formula: C₂₁H₂₇N₅O₉S₂

Peso molecolare: 557.5972

Ref: 41-Y0001318

Cefpodoxime Proxetil

CAS: 87239-81-4

Antibiotics nesoi

Formula: C₂₁H₂₇N₅O₉S₂

Colore e forma: White Light Brown Powder

Peso molecolare: 557.59 g/mol

Ref: 45-1098027

Cefpodoxime proxetil

CAS: 87239-81-4

Formula: C₂₁H₂₇N₅O₉S₂

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 557.5972

Ref: IN-DA004JC1

Cefpodoxime proxetil

CAS: 87239-81-4

Cefpodoxime proxetil

Purezza: ≥98%

Peso molecolare: 557.6g/mol

Ref: 54-BUP13928

Cefpodoxime Proxetil (Mixture of Diastereomers)

CAS: 87239-81-4

Formula: C₂₁H₂₇N₅O₉S₂

Colore e forma: Pale Yellow Solid

Peso molecolare: 557.59

Ref: 4Z-C-859

Cefpodoxime proxetil

CAS: 87239-81-4

Formula: C₂₁H₂₇N₅O₉S₂

Purezza: ≥ 70.0% (Cefpodoxime acid)

Colore e forma: White to pale yellow powder

Peso molecolare: 557.60

Ref: 7W-GA2186

Cefpodoxime proxetil

CAS: 87239-81-4

Oral 3rd-gen cephalosporin antibiotic; treats ear, throat, sinus infections; active vs. Gram+ & Gram- bacteria; Cefpodoxime proxetil is a prodrug.

Formula: C₂₁H₂₇N₅O₉S₂

Purezza: 99.07% - 99.81%

Colore e forma: A White Or Almost White Crystalline Powder

Peso molecolare: 557.6

Ref: TM-T4998

Cefpodoxime Proxetil RS

CAS: 87239-81-4

Colore e forma: White To Light Brown-White Solid Powder

Ref: 2K-7000610021

Cefpodoxime Proxetil-d7 (~85%)

Prodotto controllato

CAS: 87239-81-4

Applications Cefpodoxime Proxetil-d7 is the labelled form of Cefpodoxime Proxetil (C243860), an antibacterial. Cefpodoxime Proxetil is a broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime (C243850).
References Fujimoto, K., et al.: J. Antibiot., 40, 370 (1987), Utsui, Y., et al.: Antimicrob. Agents Chemother., 31, 1085 (1987),

Formula: C₂₁H₂₀D₇N₅O₉S₂

Purezza: ~85%

Colore e forma: Neat

Peso molecolare: 564.64

Ref: TR-C243862

Cefpodoxime Proxetil

CAS: 87239-81-4

Applications An antibacterial. A broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime.
References Fujimoto, K., et al.: J. Antibiot., 40, 370 (1987), Utsui, Y., et al.: Antimicrob. Agents Chemother., 31, 1085 (1987),

Formula: C₂₁H₂₇N₅O₉S₂

Colore e forma: White To Light Yellow

Peso molecolare: 557.60

Ref: TR-C243860

Cefpodoxime proxetil

CAS: 87239-81-4

Cefpodoxime proxetil is a prodrug of cefpodoxime with action on bacterial cell wall synthesis and is used for treating bacterial infections such as pneumonia, bronchitis, and gonorrhea.

Formula: C₂₁H₂₇N₅O₉S₂

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 557.6 g/mol

Ref: 3D-FC19867