CAS 879562-26-2

(5-Metil-2-osso-1,3-diossol-4-il)metile 4-(1-metiletenil)-2-propil-1-[[2'-(2H-tetrazol-5-il)[1,1'-bifenil]-4-il]metile]-1H-imidazolo-5-carbossilato

Descrizione:

La sostanza chimica con il nome "(5-Metil-2-osso-1,3-diossol-4-il)metile 4-(1-metiletenil)-2-propil-1-[[2'-(2H-tetrazol-5-il)[1,1'-bifenil]-4-il]metile]-1H-imidazolo-5-carbossilato" e numero CAS 879562-26-2 è un composto organico complesso caratterizzato dai suoi diversi gruppi funzionali e caratteristiche strutturali. Contiene un anello di dioxolano, che contribuisce alla sua potenziale reattività e stabilità, così come un moiety di imidazolo che può conferire attività biologica. La presenza di un gruppo tetrazolo suggerisce potenziali applicazioni in chimica medicinale, in particolare nello sviluppo di farmaci. La struttura del composto indica che potrebbe presentare proprietà lipofile a causa della presenza di gruppi alchile e vinile, che possono influenzare la sua solubilità e permeabilità nei sistemi biologici. Inoltre, la struttura bifenilica può migliorare le sue interazioni con obiettivi biologici. In generale, la combinazione unica di gruppi funzionali ed elementi strutturali di questo composto lo posiziona come un candidato per ulteriori indagini in varie applicazioni chimiche e biologiche.

Formula: C₂₉H₂₈N₆O₅

InChI: InChI=1S/C29H28N6O5/c1-5-8-24-30-25(17(2)3)26(28(36)38-16-23-18(4)39-29(37)40-23)35(24)15-19-11-13-20(14-12-19)21-9-6-7-10-22(21)27-31-33-34-32-27/h6-7,9-14H,2,5,8,15-16H2,1,3-4H3,(H,31,32,33,34)

InChI key: InChIKey=PSFJJUXSEHXDFN-UHFFFAOYSA-N

SMILES: C(N1C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(C)=C)N=C1CCC)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5

Sinonimi:

• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2′-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-carboxylate
• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-methylethenyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate
• 1H-Imidazole-5-carboxylic acid, 4-(1-methylethenyl)-2-propyl-1-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 1H-Imidazole-5-carboxylic acid, 4-(1-methylethenyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• Olmesartan medoxomil impurity I

4-(1-Methylethenyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-Imidazole-5-carboxylic acid(5-methyl-2-oxo-1,3-dioxol-4-yl)methylester

CAS: 879562-26-2

Formula: C₂₉H₂₈N₆O₅

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 540.5698

Ref: IN-DA00GWNE

Olmesartan Medoxomil EP Impurity C

CAS: 879562-26-2

Formula: C₂₉H₂₈N₆O₅

Colore e forma: White To Off-White Solid

Peso molecolare: 540.58

Ref: 4Z-O-0814

(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-carboxylate

CAS: 879562-26-2

(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-carboxylate

Purezza: 99%

Peso molecolare: 540.58g/mol

Ref: 54-OR1066772

Olmesartan medoxomil impurity C

CAS: 879562-26-2

Impurity C of Olmesartan medoxomil is a selective AT1 inhibitor with an IC50 of 66.2 μM.

Formula: C₂₉H₂₈N₆O₅

Colore e forma: Solid

Peso molecolare: 540.57

Ref: TM-T36006

(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-Methylethenyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylate

CAS: 879562-26-2

Colore e forma: Neat

Ref: 86-MM1317.03

Dehydro Olmesartan Medoxomil

Prodotto controllato

CAS: 879562-26-2

Impurity Olmesartan EP Impurity C/ Olmesartan Impurity RNH 6373
Applications Dehydro Olmesartan Medoxomil (Olmesartan EP Impurity C) is an intermediate used in the process for purifying Olmesartan Medoxomil.
References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996),

Formula: C₂₉H₂₈N₆O₅

Colore e forma: Neat

Peso molecolare: 540.57

Ref: TR-D229965

Olmesartan EP Impurity C

CAS: 879562-26-2

Formula: C₂₉H₂₈N₆O₅

Peso molecolare: 540.57

Ref: ST-EA-CP-O7003

Olmesartan EP Impurity C

CAS: 879562-26-2

Olmesartan medoxomil is a prodrug that is metabolized to the active form, olmesartan, in the liver. The esters of olmesartan medoxomil are metabolized by hydrolysis and by esterases. The most common side effects of olmesartan medoxomil are headache, dizziness, fatigue, nausea and diarrhea. Olmesartan medoxomil is used for the treatment of high blood pressure in adults. This drug also has anti-inflammatory properties due to its inhibition of prostaglandin synthesis.

Formula: C₂₉H₂₈N₆O₅

Purezza: Min. 95%

Colore e forma: White Off-White Powder

Peso molecolare: 540.57 g/mol

Ref: 3D-IO175875