CAS 88889-14-9

Fosinopril sodico

Descrizione:

Fosinopril sodico è un inibitore dell'enzima di conversione dell'angiotensina (ACE) utilizzato principalmente nel trattamento dell'ipertensione e dell'insufficienza cardiaca. È un pro-farmaco che viene convertito nel corpo nella sua forma attiva, fosinoprilato, che inibisce l'enzima ACE, portando a una diminuzione della produzione di angiotensina II, un potente vasocostrittore. Questo porta a vasodilatazione, riduzione della pressione sanguigna e diminuzione del carico di lavoro del cuore. Fosinopril sodico è caratterizzato dalla sua struttura unica, che include un gruppo acido fosfinico, contribuendo al suo meccanismo d'azione. Viene tipicamente somministrato per via orale e ha una emivita relativamente lunga, consentendo una somministrazione una volta al giorno. Gli effetti collaterali comuni possono includere vertigini, tosse e livelli elevati di potassio. Come altri inibitori dell'ACE, è controindicato in gravidanza e deve essere usato con cautela nei pazienti con insufficienza renale. In generale, Fosinopril sodico è un farmaco efficace per la gestione delle condizioni cardiovascolari, con un profilo di sicurezza ben stabilito quando usato correttamente.

Formula: C₃₀H₄₆NNaO₇P

InChI: InChI=1/C30H46NO7P.Na/c1-4-28(33)37-30(22(2)3)38-39(36,18-12-11-15-23-13-7-5-8-14-23)21-27(32)31-20-25(19-26(31)29(34)35)24-16-9-6-10-17-24;/h5,7-8,13-14,22,24-26,30H,4,6,9-12,15-21H2,1-3H3,(H,34,35);/q;+1/p-1/t25-,26+,30+,39-;/m1./s1

InChI key: InChIKey=NIDZYXQFQSHBTG-WATAJHSMSA-N

SMILES: C(CP(O[C@H](OC(CC)=O)[C@@H](C)C)(CCCCC1=CC=CC=C1)=O)(=O)N2C[C@@H](C[C@H]2C(O)=O)[C@H]3CCCCC3.[Na]

Sinonimi:

• (4S)-4-Cyclohexyl-1-{[(RS)-2-methyl-1-(propionyloxy)propoxy]-(4-phenylbutyl)phosphinylacetyl}-L-proline sodium salt
• (4S)-4-cyclohexyl-1-{[(R)-[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl]acetyl}-L-proline
• (4S)-4-cyclohexyl-1-{[{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}-L-proline
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
• <span class="text-smallcaps">L</span>-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
• Acecor
• Eosinopril
• Fosenopril sodium
• Monopril
• Secorvas
• Sq 28555
• Staril
• sodium (2S,4S)-4-cyclohexyl-1-({[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylate
• sodium (2S,4S)-4-cyclohexyl-1-{[(R)-{[(1S)-2-methyl-1-(propanoyloxy)propyl]oxy}(4-phenylbutyl)phosphoryl]acetyl}pyrrolidine-2-carboxylate
• L-Proline, 4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt (1:1), (4S)-
• L-Proline, 4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-
• Fosinopril sodium
• L-Proline, 4-cyclohexyl-1-[[[2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, [1[S*(R*)],2α,4β]-
• ELIDIUR
• (4S)-4-CYCLOHEXYL-1-[[(R)-[(1S)-2-METHYL-1-(1-OXOPROPOXY)PROPOXY](4-PHENYLBUTYL)PHOSPHINYL]ACETYL]-L-PROLINE
• 4β-Cyclohexyl-1-[[[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline sodium salt
• FOSINOPRIL-D5 SODIUM SALT
• FOSINOPRIL SODIUM SALT
• FOSINORM
• Forsinopril sodium salt
• FOSINOPRIL NA
• Dynacil, Elidiur, Fosinorm, Monopril, Staril, Tensozide, (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline
• TENSOZIDE
• FOSINPRIL SODIUM

FOSINOPRIL SODIUM CRS

CAS: 88889-14-9

FOSINOPRIL SODIUM CRS

Formula: C₃₀H₄₆NO₇P

Colore e forma: Powder

Peso molecolare: 563.6625

Ref: 41-Y0001227

Fosinopril sodium

CAS: 88889-14-9

Fosinopril sodium

Formula: C₃₀H₄₅NNaO₇P

Purezza: 99.5%

Colore e forma: Off-White

Peso molecolare: 585.28313

Ref: 47-1091

Fosinopril Sodium

CAS: 88889-14-9

Cardiovascular drugs, not elsewhere specified or includ

Formula: C₃₀H₄₅NO₇PNa

Colore e forma: Powder

Peso molecolare: 585.28313

Ref: 45-1283404

L-Proline,4-cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-, sodium salt, (4S)-

CAS: 88889-14-9

Formula: C₃₀H₄₅NNaO₇P

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 585.6443

Ref: IN-DA00IFIB

Fosinopril sodium

CAS: 88889-14-9

Fosinopril sodium: ACE inhibitor prodrug for hypertension, becomes active metabolite fosinoprilat.

Formula: C₃₀H₄₅NO₇P·Na

Purezza: 99.37% - 99.40%

Colore e forma: White To Off-White Crystalline Solid

Peso molecolare: 585.65

Ref: TM-T1489

Fosinopril Sodium Salt

CAS: 88889-14-9

Formula: C₃₀H₄₅NO₇P·Na

Colore e forma: White To Off-White Solid

Peso molecolare: 585.66

Ref: 4Z-F-121

Fosinopril Sodium

CAS: 88889-14-9

Fosinopril Sodium

Purezza: 98%

Peso molecolare: 586.64g/mol

Ref: 54-OR1029490

Fosinopril sodium

CAS: 88889-14-9

Fosinopril sodium

Purezza: ≥98%

Peso molecolare: 585.65g/mol

Ref: 54-BUP11288

Fosinopril sodium salt

CAS: 88889-14-9

Formula: C₃₀H₄₅NO₇P·Na

Peso molecolare: 585.64

Ref: 7W-GP0614

Fosinopril-d5 Sodium Salt

CAS: 88889-14-9

Formula: C₃₀H₄₀D₅NO₇P·Na

Colore e forma: White To Off-White Solid

Peso molecolare: 567.70 22.99

Ref: 4Z-F-1218

Fosinopril Sodium

CAS: 88889-14-9

Formula: C₃₀H₄₅NNaO₇P

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 585.65

Ref: 3B-F1242

Fosinopril Sodium

CAS: 88889-14-9

Colore e forma: Neat

Ref: 86-MM0645.00

Fosinopril Sodium Salt

CAS: 88889-14-9

Applications A phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988), Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988),

Formula: C₃₀H₄₅NO₇P·Na

Colore e forma: Neat

Peso molecolare: 585.64

Ref: TR-F727800

Fosinopril sodium

CAS: 88889-14-9

Angiotensin converting enzyme inhibitor

Formula: C₃₀H₄₅NNaO₇P

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 585.64 g/mol

Ref: 3D-FF23598

Fosinopril sodium salt - Bio-X ™

CAS: 88889-14-9

Fosinopril belongs to the angiotensin-converting enzyme (ACE) inhibitor class of drugs, which prevents the conversion of angiotensin I to angiotensin II. This leads to decreases in blood pressure and slows down the progression of kidney disease, hypertension and heart failure.

Formula: C₃₀H₄₆NO₇P•Na

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 586.65 g/mol

Ref: 3D-BF164489