CAS 889461-57-8

(1S,​2S)​-1,​2-​Cyclopropanedicarbox​ylic Acid 1,​2-​Diethyl Ester

Prodotto controllato

CAS: 889461-57-8

Applications (1S,​2S)​-1,​2-​Cyclopropanedicarbox​ylic Acid 1,​2-​Diethyl Ester is an intermediate in synthesizing (O846925), (2S,3S)-2,3-Oxiranedicarboxylic Acid Monoethyl Ester is used in the synthesis of aza-peptidyl inhibitors of lysosomal asparaginyl endopeptidase, legumain. Also used in the synthesis of irreversible epidermal growth factor receptor inhibitors and probes for cathespins.
References Lee, J. et al.: Bioorg. Med. Chem. Lett., 22, 1340 (2012); Carmi, C. et al.: J. Med. Chem., 53, 2038 (2010); Hillaert, U. et al.: Angew. Chem. Int. Ed., 48, 1629 (2009);

Formula: C₉H₁₄O₄

Colore e forma: Neat

Peso molecolare: 186.205

Ref: TR-C990413