CAS 90098-04-7

Rebamipide

Descrizione:

Rebamipide è un composto sintetico utilizzato principalmente nel trattamento di lesioni e ulcere della mucosa gastrica. È classificato come un agente gastroprotettivo ed è noto per la sua capacità di migliorare i meccanismi di difesa della mucosa. La struttura chimica di Rebamipide include un moiety di 2-amminobenzotiazolo, che contribuisce alle sue proprietà farmacologiche. Mostra effetti anti-infiammatori e promuove la sintesi delle prostaglandine, che sono cruciali per mantenere l'integrità della mucosa gastrica. Inoltre, Rebamipide ha proprietà antiossidanti, aiutando a neutralizzare i radicali liberi che possono danneggiare i tessuti gastrici. Il composto è tipicamente somministrato per via orale ed è ben assorbito nel tratto gastrointestinale. I suoi effetti terapeutici sono attribuiti alla sua capacità di stimolare la produzione di muco e bicarbonato, proteggendo così il rivestimento gastrico da sostanze nocive e promuovendo la guarigione. In generale, Rebamipide è riconosciuto per il suo ruolo nel migliorare la difesa della mucosa gastrica ed è utilizzato in vari disturbi gastrointestinali.

Formula: C₁₉H₁₅ClN₂O₄

InChI: InChI=1/C19H15ClN2O4/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26)/t16-/m1/s1

InChI key: InChIKey=ALLWOAVDORUJLA-UHFFFAOYSA-N

SMILES: C(C(NC(=O)C1=CC=C(Cl)C=C1)C(O)=O)C=2C=3C(NC(=O)C2)=CC=CC3

Sinonimi:

• (+-)-1,2-Dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoic acid
• +-)-2-(4-Chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid
• 2-(4-Chloro-benzoylamino)-3-(2-hydroxy-quinolin-4-yl)-propionic acid
• 2-(4-Chloro-benzoylamino)-3-(2-oxo-1,2-dihydro-quinolin-4-yl)-propionic acid
• 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid
• 2-[(4-Chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (R)-
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-, (S)-
• 4-Quinolinepropanoic acid, α-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-
• Mucosta
• N-(4-chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)-D-alanine
• N-(4-chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)alanine
• Opc 12759
• Proamipide
• Rebator
• α-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid
• Rebamipide
• (+-)-1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoica
• 4-Quinolinepropanoic acid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-(9CI)
• REBAPIMIDE
• Rebamipid
• 2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-
• 2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoicaci
• (+-)-2-(4-chlorobenzoylamino)-3-(2(1h)-quinolinon-4-yl)propionicacid
• 2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-(+-)-4-quinolinepropanoic acid
• 2-(4-CHLOROBENZAMIDO)-3-(2-OXO-1,2-DIHYDROQUINOLIN-4-YL)PROPANOIC ACID
• RebamipideRebamipide
• 1,2-dihydro-alpha-((4-chlorobenzoyl)amino)-2-oxo-4-quinolinepropanoicaci(
• opc12759
• REBAMIPIDE,99.5%
• OPC-12759, Mucosta, α-[(4-Chlorobenzoyl)-amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic Acid

2-​(4-​Chloro-​benzoylamino)​-​3-​(2-​hydroxy-​quinolin-​4-​yl)​-​propionic acid

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 370.7864

Ref: IN-DA00IMK8

Rebamipide

CAS: 90098-04-7

Rebamipide (OPC12759) is a drug enhancing gastric defense by stimulating COX2, prostaglandins, and mucus, while reducing TNF alpha and free radicals.

Formula: C₁₉H₁₅ClN₂O₄

Purezza: 99.48% - 99.61%

Colore e forma: White Powder

Peso molecolare: 370.79

Ref: TM-T1562

Rebamipide

CAS: 90098-04-7

Rebamipide

Purezza: ≥98%

Peso molecolare: 370.79g/mol

Ref: 54-BUP18316

Rebamipide hydrate

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄·xH₂O

Purezza: ≥ 99.0% (dried basis)

Colore e forma: White crystalline powder

Peso molecolare: 370.79 (anhydrous)

Ref: 7W-GP6330

Rebamipide

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 370.79

Ref: 4Z-R-085005

2-(4-Chlorobenzamido)-3-(2-Oxo-1,2-Dihydroquinolin-4-Yl)Propanoic Acid

CAS: 90098-04-7

2-(4-Chlorobenzamido)-3-(2-Oxo-1,2-Dihydroquinolin-4-Yl)Propanoic Acid

Purezza: 98%

Peso molecolare: 370.79g/mol

Ref: 54-OR1009762

Rebamipide

CAS: 90098-04-7

Formula: C₁₉H₁₅ClN₂O₄

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 370.79

Ref: 3B-R0085

2-(4-CHLOROBENZOYLAMINO)-3-(1,2-DIHYDRO-2-OXO-4-QUINOLYL)PROPIONIC ACID

CAS: 90098-04-7

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 370.7900085449219

Ref: 10-F300998

Rebamipide

Prodotto controllato

CAS: 90098-04-7

Applications Shows antiulcer activity in rats.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Uchida, M., et al.: Chem. Pharm. Bull., 33, 3775 (1985), Yamasaki, K., et al.: Eur. J. Pharmacol., 142, 23 (1987),

Formula: C₁₉H₁₅ClN₂O₄

Colore e forma: Off-White

Peso molecolare: 370.79

Ref: TR-R139000

Rebamipide - Bio-X ™

CAS: 90098-04-7

Rebamipide is a gastroprotective agent that is used to treat various gastrointestinal disorders such as gastric ulcers and GERD. This drug’s mechanism of action is not fully understood however, it is thought to exert its effects by promoting the secretion of protective mucus in the stomach and intestine, which helps to create a barrier against stomach acid and other irritants. Additionally, it has antioxidant and anti-inflammatory properties that can help reduce tissue damage.

Formula: C₁₉H₁₅ClN₂O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 370.79 g/mol

Ref: 3D-BC164330

Rebamipide

CAS: 90098-04-7

COX-2 positive regulator; gastroprotective; anti-inflammatory; anti-ulcer agent

Formula: C₁₉H₁₅ClN₂O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 370.79 g/mol

Ref: 3D-FC15908