CAS 9011-18-1

Solfato di destrano sodico

Descrizione:

Solfato di destrano sodico è un polisaccaride solfato derivato dal destrosio, un glucano ramificato complesso. È caratterizzato da un alto peso molecolare ed è tipicamente utilizzato come anticoagulante e in varie applicazioni biomediche. La sostanza appare come una polvere bianca o bianco sporco ed è solubile in acqua, formando una soluzione viscosa. Solfato di destrano sodico presenta una carica negativa a causa dei gruppi solfato, il che contribuisce alla sua capacità di interagire con proteine e altre biomolecole, rendendolo utile nei sistemi di somministrazione di farmaci e come agente stabilizzante in varie formulazioni. Inoltre, è stato studiato per i suoi potenziali effetti terapeutici, comprese le proprietà antivirali e anti-infiammatorie. Il suo profilo di sicurezza è generalmente favorevole, ma può causare reazioni avverse in alcuni individui, in particolare ad alte concentrazioni. Come per qualsiasi sostanza chimica, devono essere seguite le linee guida appropriate per la manipolazione e l'uso per garantire sicurezza ed efficacia nelle sue applicazioni.

Formula: H₂O₄S·xNa·xUnspecified

Sinonimi:

• Asuro
• Colyonal
• Dexnon
• Dextralip 15
• Dextran Sulfate Sodium
• Dextran sodium sulfate
• Dextran sulfate sodium salt
• Dextran sulfuric acid ester sodium salt
• Dextran, hydrogen sulfate, sodium salt
• Dextransulfate sodium sulfur
• Dextrarine
• Dexulate
• MDS (polysaccharide)
• MDS-Kowa A

Dextran sulfate sodium, MW 100,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Colore e forma: Powder

Ref: 3D-YD59549

Dextran sulfate sodium, MW 50,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Colore e forma: Powder

Ref: 3D-YD59741

Dextran sulfate sodium salt - MW 500,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Formula: C₉H₁₁NO₂

Purezza: Min. 95%

Colore e forma: White Powder

Ref: 3D-YD32562

Dextran sulfate sodium - MW 8,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Colore e forma: White Powder

Peso molecolare: 8000.0

Ref: 3D-YD59550

Dextran sulfate sodium - MW 5,000-8,000

CAS: 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Formula: (C₆H₇Na₃O₁₄S₃)n

Purezza: Min. 95%

Colore e forma: Powder

Ref: 3D-YD31801

Dextran Sulphate Sodium Salt 30-50(DSS 35-50) ex. Leuconostoc Sp.Colitis Grade for molecular biology

CAS: 9011-18-1

Colore e forma: White to off-white, Powder, Clear, Colourless to pale yellow

Peso molecolare: made from Dextran 35 - 50 KDa

Ref: SR-76203

Dextran Sulphate Sodium Salt 500 (DSS 500) ex. Leuconostoc Sp. for molecular biology

CAS: 9011-18-1

Colore e forma: White to pale yellow, Powder, Clear

Peso molecolare: made from Dextran 500 KDa

Ref: SR-99629

Dextran sulfate sodium - MW 3000-6000

CAS: 9011-18-1

Dextran sulfate sodium is a complex carbohydrate that consists of a linear chain of many glucose molecules. It is often used as a gel to protect the bowel during radiation therapy and in the treatment of severe burns. Dextran sulfate sodium can be modified with methylation, click modification, fluorination, saccharide, or glycosylation. Dextran sulfate sodium also has many applications in biochemistry and medicine such as being used as an osmotic agent in cell culture media, after being glycosylated it can be used to treat inflammatory bowel disease. This product is custom synthesized by our company and is available in various sizes from MW 3000-6000.

Purezza: Min. 95%

Colore e forma: Powder

Ref: 3D-YD176024

Dextran sulfate sodium salt - MW 150,000

CAS: 9011-18-1

Induces ulceration; used to model inflammatory bowel disease

Purezza: Min. 95%

Colore e forma: Powder

Ref: 3D-OD157161