CAS 90332-64-2

10-Desacetil-7-xilosiltaxolo B

Descrizione:

10-Desacetil-7-xilosiltaxolo B, identificato dal suo numero CAS 90332-64-2, è un composto chimico che appartiene alla classe dei taxani, noti per le loro complesse strutture policicliche e significativa attività biologica. Questa sostanza è caratterizzata dal suo unico schema molecolare, che include un nucleo di taxano modificato dalla presenza di un gruppo xilosilico e dall'assenza di un gruppo acetile nella posizione 10. Il composto presenta notevoli proprietà farmacologiche, in particolare nel contesto del trattamento del cancro, poiché i taxani sono spesso utilizzati per la loro capacità di inibire la divisione cellulare stabilizzando i microtubuli. Inoltre, la presenza del gruppo xilosilico può influenzare la sua solubilità e biodisponibilità, influenzando potenzialmente la sua efficacia terapeutica. Come molti prodotti naturali derivati da fonti vegetali, il composto può anche presentare una gamma di attività biologiche oltre ai suoi effetti antitumorali, rendendolo un argomento di interesse per ulteriori ricerche in chimica medicinale e farmacologia.

Formula: C₄₈H₅₉NO₁₇

InChI: InChI=1S/C48H59NO17/c1-8-23(2)41(57)49-33(26-15-11-9-12-16-26)36(54)43(59)63-29-20-48(60)40(65-42(58)27-17-13-10-14-18-27)38-46(7,39(56)35(53)32(24(29)3)45(48,5)6)30(19-31-47(38,22-62-31)66-25(4)50)64-44-37(55)34(52)28(51)21-61-44/h8-18,28-31,33-38,40,44,51-55,60H,19-22H2,1-7H3,(H,49,57)/b23-8+/t28-,29+,30+,31-,33+,34+,35-,36-,37-,38+,40+,44+,46-,47+,48-/m1/s1

InChI key: InChIKey=YAOWLIDDDUBAEI-ZVZSAYPQSA-N

SMILES: O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)CO4)C[C@]1(OC2)[H])C(=O)[C@H](O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(/C(=C/C)/C)=O)C7=CC=CC=C7)O)=O)C5C)[H]

Sinonimi:

• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
• 10-Deacetylcephalomannine 7-xyloside
• Benzenepropanoic acid, α-hydroxy-β-[(2-methyl-1-oxo-2-butenyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9a[αR*,βS*(E)],11α,12α,12aα,12bα]]-
• Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester
• Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-butenyl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• 7-Xylosyl-10-deacetylcephalomannine
• 10-Deacetyl-7-xylosyltaxol B
• Benzenepropanoic acid, α-hydroxy-β-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2...
• 7-Xylosyl-10-deacetyltaxol B
• DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)

DEACETYL-7-XYLOSYLCEPHALOMANNINE, 10-(RG)

CAS: 90332-64-2

Formula: C₄₈H₅₉NO₁₇

Purezza: 98%

Peso molecolare: 921.9786

Ref: IN-DA00H097

7-Xylosyl-10-deacetyltaxol B

CAS: 90332-64-2

7-Xylosyl-10-deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) is a paclitaxel derivative with antitumour activity that is used in the synthesis of paclitaxel

Formula: C₄₈H₅₉NO₁₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 921.98

Ref: TM-TN1335

7-Xylosyl-10-deacetyltaxol B

CAS: 90332-64-2

Formula: C₄₈H₅₉NO₁₇

Purezza: 95%~99%

Peso molecolare: 921.99

Ref: BP-SBP03711

7-Xylosyl-10-deacetyltaxol B

CAS: 90332-64-2

7-Xylosyl-10-deacetyltaxol B is a natural product derivative, which is a taxoid compound commonly isolated from yew tree species such as Taxus brevifolia. This derivative is structurally adapted from the well-known chemotherapeutic agent paclitaxel. The source, primarily the bark and needles of yew plants, provides a rich repository of taxanes, which are crucial for their cytotoxic properties against cancer cells.

Formula: C₄₈H₅₉NO₁₇

Purezza: Min. 95%

Peso molecolare: 922 g/mol

Ref: 3D-QDA33264