CAS 90332-65-3

7-Xilosil-10-deacetiltaxolo C

Descrizione:

7-Xilosil-10-deacetiltaxolo C, con il numero CAS 90332-65-3, è un composto chimico che appartiene alla famiglia dei tassani, nota per il suo ruolo nel trattamento del cancro grazie alla sua capacità di inibire la divisione cellulare. Questo composto presenta un gruppo xilosilico, che è una porzione di zucchero, attaccato alla struttura del tassano, migliorando la sua solubilità e potenzialmente la sua attività biologica. La presenza della forma desacetilata indica che manca di un gruppo acetile, il che può influenzare la sua farmacocinetica e l'efficacia terapeutica. I tassani, inclusi i derivati come questo, mostrano tipicamente significative proprietà antitumorali stabilizzando i microtubuli e prevenendo la loro depolimerizzazione, interrompendo così il normale processo mitotico nelle cellule tumorali. Le caratteristiche specifiche, come solubilità, stabilità e attività biologica, dipenderebbero dalla sua struttura molecolare e dai gruppi funzionali presenti. Ulteriori studi sarebbero necessari per chiarire completamente il suo profilo farmacologico e le potenziali applicazioni in oncologia.

Formula: C₄₉H₆₃NO₁₇

InChI: InChI=1S/C49H63NO17/c1-7-8-11-20-33(53)50-35(27-16-12-9-13-17-27)38(56)44(60)64-30-22-49(61)42(66-43(59)28-18-14-10-15-19-28)40-47(6,41(58)37(55)34(25(30)2)46(49,4)5)31(21-32-48(40,24-63-32)67-26(3)51)65-45-39(57)36(54)29(52)23-62-45/h9-10,12-19,29-32,35-40,42,45,52,54-57,61H,7-8,11,20-24H2,1-6H3,(H,50,53)/t29-,30+,31+,32-,35+,36+,37-,38-,39-,40+,42+,45+,47-,48+,49-/m1/s1

InChI key: InChIKey=XGWGQEYABFGJID-UVDBIDMBSA-N

SMILES: O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)CO4)C[C@]1(OC2)[H])C(=O)[C@H](O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(CCCCC)=O)C7=CC=CC=C7)O)=O)C5C)[H]

Sinonimi:

• 10-Deacetyl-7-xylosyltaxol C
• 10-Deacetylpaclitaxel C 7-xyloside
• 10-Deacetyltaxol C 7-xyloside
• 7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.
• 7-(b-Xylosyl)-10-deacetyltaxol C
• 7-Xylosyl-10-deacetyltaxol C
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-<span class="text-smallcaps">D</span>-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-<span class="text-smallcaps">D</span>-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Benzenepropanoicacid, a-hydroxy-b-[(1-oxohexyl)amino]-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(b-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester, [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-
• Benzenepropanoic acid, α-hydroxy-β-[(1-oxohexyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(β-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

7-Xylosyl-10-deacetyltaxol C

CAS: 90332-65-3

7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc.

Formula: C₄₉H₆₃NO₁₇

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 938.033

Ref: TM-TN1336

7-Xylosyl-10-deacetyltaxol C

CAS: 90332-65-3

Formula: C₄₉H₆₃NO₁₇

Purezza: 95%~99%

Peso molecolare: 938.033

Ref: BP-SBP03706

Deacetyl-7-xylosyltaxol C

CAS: 90332-65-3

Deacetyl-7-xylosyltaxol C is a complex taxol derivative, which is a naturally occurring compound obtained from the bark of the Pacific yew tree, Taxus brevifolia, and other related species. This unique derivative is structurally modified by the removal of an acetyl group and the addition of a xylose moiety, which is characteristic of its taxonomy.

Formula: C₄₉H₆₃NO₁₇

Purezza: Min. 95%

Peso molecolare: 938 g/mol

Ref: 3D-QDA33265