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CAS 90357-51-0
:N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-ossiranecarbossamide
Descrizione:
N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-ossiranecarbossamide, con il numero CAS 90357-51-0, è un composto chimico caratterizzato dalla sua struttura unica, che include un gruppo funzionale epossidico (ossirano) e un gruppo ciano attaccato a un anello fenilico. La presenza di un gruppo trifluorometilico migliora la sua stabilità chimica e lipofilia, rendendolo potenzialmente utile in varie applicazioni, tra cui prodotti farmaceutici e agrochimici. La funzionalità epossidica del composto suggerisce che potrebbe partecipare a reazioni di apertura dell'anello, che possono portare alla formazione di diversi derivati. Inoltre, il gruppo ciano può contribuire alla reattività e polarità del composto, influenzando la sua solubilità e interazione con sistemi biologici. In generale, le caratteristiche distintive di questo composto lo rendono un argomento di interesse nella chimica sintetica e nella scienza dei materiali, sebbene applicazioni specifiche dipenderebbero da ulteriori ricerche sulle sue proprietà e comportamento in diversi ambienti.
Formula:C12H9F3N2O2
InChI:InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)
InChI key:InChIKey=UQUQTWDUTIAAAY-UHFFFAOYSA-N
SMILES:C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)(=O)C2(C)CO2
Sinonimi:- 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)]
- 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide
- 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide
- 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide
- 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide
- Carboxamide
- N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide
- N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide
- N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide
- N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide
- N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
- Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
- Phenyl]-2-methyl-2-oxirane
- Vedi altri sinonimi
Ordinare per
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10 prodotti.
Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
CAS:Formula:C12H9F3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:270.2073Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity)
CAS:Formula:C12H9F3N2O2Colore e forma:White To Off-White SolidPeso molecolare:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamidePurezza:98%Peso molecolare:270.21g/mol1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide
CAS:Prodotto controllatoFormula:C12H9F3N2O2Colore e forma:NeatPeso molecolare:270.21N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:Formula:C12H9F3N2O2Purezza:>95.0%(GC)Colore e forma:White to Almost white powder to crystalPeso molecolare:270.21Ref: ST-EA-CP-B12017
10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaN-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
CAS:Prodotto controllatoImpurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity
Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);Formula:C12H9F3N2O2Colore e forma:NeatPeso molecolare:270.21N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide
CAS:Formula:C12H9F3N2O2Purezza:98%Colore e forma:SolidPeso molecolare:270.211N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
CAS:N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.Formula:C12H9F3N2O2Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:270.21 g/mol
![Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IG48.jpg&w=3840&q=75)
![1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0894.11.jpg&w=3840&q=75)
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![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FC987585.jpg&w=3840&q=75)
![N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb%2FIC58274.jpg&w=3840&q=75)
