CAS 90357-51-0

N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-ossiranecarbossamide

Descrizione:

N-[4-Ciano-3-(trifluorometil)fenil]-2-metil-2-ossiranecarbossamide, con il numero CAS 90357-51-0, è un composto chimico caratterizzato dalla sua struttura unica, che include un gruppo funzionale epossidico (ossirano) e un gruppo ciano attaccato a un anello fenilico. La presenza di un gruppo trifluorometilico migliora la sua stabilità chimica e lipofilia, rendendolo potenzialmente utile in varie applicazioni, tra cui prodotti farmaceutici e agrochimici. La funzionalità epossidica del composto suggerisce che potrebbe partecipare a reazioni di apertura dell'anello, che possono portare alla formazione di diversi derivati. Inoltre, il gruppo ciano può contribuire alla reattività e polarità del composto, influenzando la sua solubilità e interazione con sistemi biologici. In generale, le caratteristiche distintive di questo composto lo rendono un argomento di interesse nella chimica sintetica e nella scienza dei materiali, sebbene applicazioni specifiche dipenderebbero da ulteriori ricerche sulle sue proprietà e comportamento in diversi ambienti.

Formula: C₁₂H₉F₃N₂O₂

InChI: InChI=1S/C12H9F3N2O2/c1-11(6-19-11)10(18)17-8-3-2-7(5-16)9(4-8)12(13,14)15/h2-4H,6H2,1H3,(H,17,18)

InChI key: InChIKey=UQUQTWDUTIAAAY-UHFFFAOYSA-N

SMILES: C(NC1=CC(C(F)(F)F)=C(C#N)C=C1)(=O)C2(C)CO2

Sinonimi:

• 1,2-Epoxy-2-Methyl-N-[4-Cyano-3-(Trifluoromethyl)]
• 1,2-Epoxy-2-Methyl-N[4-Cyano-3(Trifluoromethyl)-Phenyl]Propanamide
• 2-Methyl-oxirane-2-carboxylic acid (4-cyano-3-trifluoromethylphenyl)-amide
• 2-Methyloxirane-2-carboxylic acid N-(4-cyano-3-trifluoromethylphenyl)amide
• 2-Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
• 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropioanilide
• Carboxamide
• N-[4-Cyano-3-(Triflouromethyl)Phenyl]-2-Methyl-2-Oxirane Carboxamide
• N-[4-Cyano-3-(Trifluoromethyl)Phenyl]Methacrylamide Epoxide
• N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
• N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-oxiranecarboxamide
• N-[4-Cyano-3-(trifluoromethyl)phenyl]-methacrylamide exoxide
• N-[4-Cyano-3-Trifluoromethy Phenyl]-2-Oxirane Carboxamide
• N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-oxiranecarboxamide
• N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide
• Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-
• Phenyl]-2-methyl-2-oxirane

Oxiranecarboxamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-methyl-

CAS: 90357-51-0

Formula: C₁₂H₉F₃N₂O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 270.2073

Ref: IN-DA00IG48

Bicalutamide Impurity 3 (Bicalutamide Epoxide Impurity)

CAS: 90357-51-0

Formula: C₁₂H₉F₃N₂O₂

Colore e forma: White To Off-White Solid

Peso molecolare: 270.21

Ref: 4Z-B-0218

N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide

CAS: 90357-51-0

N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide

Purezza: 98%

Peso molecolare: 270.21g/mol

Ref: 54-PC99703

1,2-Epoxy-2-methyl-N-[4-cyano-3-(trifluoromethyl)-phenyl]propionamide

Prodotto controllato

CAS: 90357-51-0

Formula: C₁₂H₉F₃N₂O₂

Colore e forma: Neat

Peso molecolare: 270.21

Ref: 86-MM0894.11

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide

CAS: 90357-51-0

Formula: C₁₂H₉F₃N₂O₂

Purezza: >95.0%(GC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 270.21

Ref: 3B-C3607

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide

Prodotto controllato

CAS: 90357-51-0

Impurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity
Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);

Formula: C₁₂H₉F₃N₂O₂

Colore e forma: Neat

Peso molecolare: 270.21

Ref: TR-C987585

Bicalutamide Impurity 3

CAS: 90357-51-0

Formula: C₁₂H₉F₃N₂O₂

Peso molecolare: 270.21

Ref: ST-EA-CP-B12017

N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide

CAS: 90357-51-0

Formula: C₁₂H₉F₃N₂O₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 270.211

Ref: 10-F212526

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide

CAS: 90357-51-0

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.

Formula: C₁₂H₉F₃N₂O₂

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 270.21 g/mol

Ref: 3D-IC58274