CAS 9073-60-3

β-Lattamasi

Descrizione:

β-Lattamasi è un enzima che svolge un ruolo cruciale nella resistenza agli antibiotici, in particolare contro gli antibiotici β-lattamici come le penicilline e le cefalosporine. È prodotta da vari batteri, comprese specie Gram-positive e Gram-negative. La funzione principale di β-Lattamasi è idrolizzare l'anello β-lattamico di questi antibiotici, rendendoli inefficaci e consentendo ai batteri di sopravvivere in presenza di questi farmaci. L'enzima presenta una gamma di caratteristiche, inclusa la sua capacità di variare in specificità e attività a seconda del ceppo batterico e del tipo di antibiotico β-lattamico. I β-Lattamasi possono essere classificati in diversi gruppi in base alla loro struttura molecolare e meccanismo d'azione, inclusi β-Lattamasi di serina e metallo-β-Lattamasi. La presenza di geni β-Lattamasi nelle popolazioni batteriche è una preoccupazione significativa negli ambienti clinici, poiché contribuisce al crescente problema della resistenza agli antibiotici, rendendo le infezioni più difficili da trattare. Comprendere i meccanismi e le caratteristiche dei β-Lattamasi è essenziale per sviluppare nuove strategie per combattere le infezioni resistenti agli antibiotici.

Formula: Unspecified

Sinonimi:

• 3: PN: WO2019216248 SEQID: 10 claimed DNA
• Carbapenamase
• Carbapenem hydrolase
• Carbapenem-hydrolyzing β-lactamase
• Carbapenemase
• Carbapenemase 1
• Cefinase
• Cefotaximase
• Ceftazidimase
• Ceftazimidase
• Cefuroximase
• Cephalosporinase
• Cephamycinase
• Cloxacilanase
• Difco Penase
• Difco Penase Concentrate
• E.C. 3.5.2.6
• E.C. 3.5.2.8
• Imipenem-hydrolyzing β-lactamase
• Imipenemase
• Lactamasa, Β-
• Lactamase
• Metallo-β-lactamase
• Metallo-β-lactamases
• Neutrapen
• Oxacillinase
• Oxyiminocephalosporinase
• Penase
• Penicilloyl serine transferase
• Proteins, gene blaZ
• β-Lactamase
• β-Lactamase II
• EC 3.5.2.6
• b-Lactamase, Bacillus cereus 569/H9
• CENTA B-LACTAMASE SUBSTRATE

LacBuster™-L concentrate

CAS: 9073-60-3

Beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL019.7

LacBuster™-L 100 (beta-lactamase)

CAS: 9073-60-3

Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.beta lactamase I activity - min. 25.0 IU/mLbeta lactamase II activity - min. 10.0 IU/mL

Ref: 3D-EBL014.3

LacBuster™ (b-lactamase) settle plates

CAS: 9073-60-3

A general purpose growth medium supplemented with LacBuster™ to effectively neutralize beta-lactam antibiotics. This product is suitable for the cultivation of a wide variety of microorganisms for environmental monitoring within the pharmaceutical industry and for high performance monitoring of your isolators and clean rooms during beta lactam manufacture

Ref: 3D-EBL061

LacBuster™-L 1000 (β-lactamase)

CAS: 9073-60-3

Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL011.3

OXA-11 (β-Lactamase)

CAS: 9073-60-3

OXA-11 (β-Lactamase) is an enzyme of the β-lactamase class, which is primarily derived from Gram-negative bacteria. This enzyme is characterized by its ability to hydrolyze β-lactam antibiotics, rendering them ineffective by breaking the β-lactam ring, a crucial component of these antibiotics. OXA-11 is a notable member of the oxacillinase group within class D β-lactamases, known for its resistance to penicillins and cephalosporins.

Ref: 3D-EB10013

LacBuster™-L bulk (β-lactamase)

CAS: 9073-60-3

Ready to use beta-lactamase solution targeting beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. According to US Pharmacopeia (USP <71>) and EP, LacBusterTM-L is suitable for sterility testing methods such as membrane filtration and direct inoculation.

Ref: 3D-EBL010.7

LacBuster™-S bulk (β-Lactamase)

CAS: 9073-60-3

This product shows beta-lactamase activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Ref: 3D-EBL020.5

LacBuster™-S bulk for plates (β-lactamase)

CAS: 9073-60-3

This product shows beta-lactamase activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Ref: 3D-EBL039.5

SPM-1 (β-Lactamase)

CAS: 9073-60-3

SPM-1 (β-Lactamase) is an enzyme, which is a type of metallo-beta-lactamase enzyme, derived from bacterial origins, specifically from pathogens associated with nosocomial infections. This enzyme acts by hydrolyzing the amide bond in the beta-lactam ring of antibiotics, rendering β-lactam antibiotics ineffective. SPM-1 participates in antibiotic resistance by facilitating the degradation of a wide range of β-lactam antibiotics, including penicillins and cephalosporins, thereby nullifying their therapeutic effects.

Ref: 3D-EBL091.5

β-Lactamase Kit 01

CAS: 9073-60-3

Beta-lactamase enzymes demonstrate activity against clinically relevant beta-lactam antibiotics such as penicillins, carbapenems and cephalosporins. This product may be of particular interest for laboratory teams who require the sterility testing of biological specimens or for environmental monitoring applications.

Ref: 3D-EBL_KIT01