CAS 90776-58-2

(R)-2-[(3S,4S)-3-[(R)-1-(tert-butil-dimetilsililossi)etil]-2-oxoazetidin-4-il]acido propionico

Descrizione:

La sostanza chimica nota come (R)-2-[(3S,4S)-3-[(R)-1-(tert-butil-dimetilsililossi)etil]-2-oxoazetidin-4-il]acido propionico, con il numero CAS 90776-58-2, è un composto chirale che presenta una struttura complessa che include un anello di azetidina e un gruppo acido propionico. La sua stereochimica è significativa, poiché contiene più centri chirali, che possono influenzare la sua attività biologica e le interazioni. La presenza del gruppo tert-butyldimethylsilyloxy suggerisce che questo composto possa essere utilizzato in chimica organica sintetica, in particolare in strategie di gruppi protettivi o come intermedio nella sintesi di molecole più complesse. L'anello di azetidina contribuisce alla rigidità del composto e può influenzare le sue proprietà farmacocinetiche. Inoltre, il componente acido propionico indica potenziali applicazioni in chimica medicinale, possibilmente come agente farmaceutico. In generale, le caratteristiche strutturali uniche e la stereochimica del composto lo rendono di interesse in vari campi, incluso lo sviluppo di farmaci e la sintesi organica.

Formula: C₁₄H₂₇NO₄Si

InChI: InChI=1S/C14H27NO4Si/c1-8(13(17)18)11-10(12(16)15-11)9(2)19-20(6,7)14(3,4)5/h8-11H,1-7H3,(H,15,16)(H,17,18)/t8-,9-,10-,11-/m1/s1

InChI key: InChIKey=NNANGMFTFSNDLW-GWOFURMSSA-N

SMILES: [C@@H](C(O)=O)(C)[C@@]1([C@@]([C@H](O[Si](C(C)(C)C)(C)C)C)(C(=O)N1)[H])[H]

Sinonimi:

• (2R)-2-{(2S,3S)-3-[(1R)-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]-4-oxoazetidin-2-yl}propanoic acid
• (3S 4S)-3-[(R)-1-(T-Butyldimethylsilyloxy)Ethyl]-4-[(R)-1-Carboxyethyl]-2-Azetidinone
• (3S,4S)-3-[(1R)-1-[(tert-Butyldimethylsilyl)oxy]ethyl]-4-((1R)-1-carboxyethyl)azetidin-2-one
• (3S,4S)-3-[(R)-(Butyldimethylsilyloxy)Ethyl]-4-[(R)-Carboxyethyl]-2-Azetidinone
• (3S,4S)-3-[(R)-1-(Tert-Butyldimethylsiloxy)Ethyl]-4-[(R)-1-Carboxyethyl]-2-Azetidinone
• (3S,4S)-3-[(R)-1-(Tert-Butyldimethylsilyloxy)Ethyl]-4-[(R)-1-Carboxyethyl]-2-Azetidinone
• (3S,4S)-4-[(R)-1-carboxy-ethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
• (3S,4S)-4-[(R)-1-carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone
• (R)-2-((2S,3S)-3-((R)-1-(Tert-Butyldimethylsilyloxy)Ethyl)-4-Oxoazetidin-2-Yl)Propanoic Acid
• (R)-2-[(3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-2-oxoazetidin-4-yl]propionic acid
• (αR,2S,3S)-3-[(1R)-1-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methyl-4-oxo-2-azetidineacetic acid
• 1-Bma
• 2-Azetidineacetic acid, 3-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methyl-4-oxo-, (αR,2S,3S)-
• 2-Azetidineacetic acid, 3-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methyl-4-oxo-, [2S-[2α(S*),3β(S*)]]-
• 4-BMA(for Meropenem)
• 4-Bma
• 4Bma
• Side Chain For Imipenem
• [2R-[2α(R*),3β(R*)] ]-3-[1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-α-methl-4-oxo-2-azetidineacetic acid

(3S,4S)-4-[(R)-1-carboxyethyl]-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-2-azetidinone

CAS: 90776-58-2

Formula: C₁₄H₂₇NO₄Si

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 301.4540

Ref: IN-DA003BTJ

(R)-2-((2S,3S)-3-((R)-1-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Oxoazetidin-2-Yl)Propanoic Acid

CAS: 90776-58-2

(R)-2-((2S,3S)-3-((R)-1-((Tert-Butyldimethylsilyl)Oxy)Ethyl)-4-Oxoazetidin-2-Yl)Propanoic Acid

Purezza: 95%

Peso molecolare: 301.45g/mol

Ref: 54-OR1008440

(3S 4S)-3-[ (R)-1-(T-Butyldimethylsilyloxy)ethyl]-4[(R)-1-carboxyethyl]-2-azetidinone

CAS: 90776-58-2

S03379 - (3S 4S)-3-[ (R)-1-(T-Butyldimethylsilyloxy)ethyl]-4[(R)-1-carboxyethyl]-2-azetidinone

Formula: C₁₄H₂₇NO₄Si

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 301.458

Ref: 10-S03379

(3S,4S)-3-((R)-(tert-Butyldimethyl-silyloxy)ethyl)-4((R)-carboxyethyl)-2-azetidinone

CAS: 90776-58-2

(3S,4S)-3-((R)-(tert-Butyldimethyl-silyloxy)ethyl)-4((R)-carboxyethyl)-2-azetidinone (SBET) is a propionylated carbapenem antibiotic. It is an analog of ertapenem, a carbapenem antibiotic that has been developed for the treatment of multidrug resistant Gram-negative bacteria. SBET has been shown to have stereospecificity in vitro studies and to be metabolized by organic acids. The reaction yields are dependent on the solvents used. The functional groups on SBET are important for its activity as a carbapenem antibiotic.

Formula: C₁₄H₂₇NO₄Si

Purezza: Min. 95%

Peso molecolare: 301.45 g/mol

Ref: 3D-FB149807