CAS 911-40-0

Acido 7-chetodesossicolico

Descrizione:

Acido 7-chetodesossicolico, noto anche come 7-keto-DCA, è un derivato degli acidi biliari caratterizzato dalla presenza di un gruppo chetonico nella posizione C7 del nucleo steroideo. È un solido bianco a bianco sporco che è solubile in solventi organici ma ha una solubilità limitata in acqua. Questo composto è un metabolita dell'acido desossicolico e gioca un ruolo in vari processi biologici, incluso il metabolismo dei lipidi e l'emulsificazione dei grassi. La sua struttura presenta uno scheletro steroideo, tipico degli acidi biliari, ed espone proprietà anfipatiche, consentendogli di interagire sia con ambienti idrofili che idrofobici. Acido 7-chetodesossicolico ha suscitato interesse nella ricerca per le sue potenziali applicazioni terapeutiche, in particolare nel contesto dei disturbi metabolici e dell'obesità. Inoltre, potrebbe influenzare le vie di segnalazione cellulare ed è stato studiato per i suoi effetti sul metabolismo del colesterolo. Come molti acidi biliari, la sua attività biologica è strettamente legata alla sua concentrazione e alla presenza di altri acidi biliari nel tratto gastrointestinale.

Formula: C₂₄H₃₈O₅

InChI: InChI=1/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,20,22,25,27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,20+,22+,23+,24-/m1/s1

InChI key: InChIKey=RHCPKKNRWFXMAT-RRWYKFPJSA-N

SMILES: O=C1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(O)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Sinonimi:

• (3a,5b,12a)-3,12-dihydroxy-7-oxo-Cholan-24-oic acid
• (3α,5β,12α)-3,12-Dihydroxy-7-oxocholan-24-oic acid
• 3A,12A-Dihydroxy-7-Oxo-5B-Cholan-24-Oic Acid
• 3α,12α-Dihydroxy-7-keto-5β-cholanic acid
• 3α,12α-Dihydroxy-7-ketocholanic acid
• 3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid
• 5β-Cholan-24-oic acid, 3α,12α-dihydroxy-7-oxo-
• 5β-Cholanic acid, 3α,12α-dihydroxy-7-oxo-
• 5β-Cholanic acid-3α,12α-diol-7-one
• 7-Ketodeoxycholic acid
• 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid
• 7-Oxo-3α,12α-dihydroxycholan-24-oic acid
• 7-Oxodeoxycholic acid
• 7-keto-3α,12α-Dihydroxy-5β-cholanic acid
• 7-keto-Deoxycholic acid
• Cholan-24-Oic Acid, 3,12-Dihydroxy-7-Oxo-, (3Alpha,5Beta,12Alpha)-
• Cholan-24-oic acid, 3,12-dihydroxy-7-oxo-, (3α,5β,12α)-
• 5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL-7-ONE
• 3,12-DIHYDROXY-7-OXOCHOLAN-24-OIC ACID
• 3α,12α-dihydroxy-7-keto-5β-cholan-24-oic acid
• 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid
• Deoxycholic Acid 7-Oxo Impurity
• 7-Ketodeoxycholic acida
• Ursodeoxycholic Acid Impurity 11
• 7-Keto-3alpha,12alpha-dihydroxycholanic acid
• 7-DEHYDROCHOLIC ACID

7-keto Deoxycholic Acid

CAS: 911-40-0

Formula: C₂₄H₃₈O₅

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 406.5555

Ref: IN-DA006QNT

Cholic Acid Impurity 12 (7-Ketodeoxy Cholic Acid)

CAS: 911-40-0

Formula: C₂₄H₃₈O₅

Peso molecolare: 406.56

Ref: 4Z-C-57119

7-Keto-3Α,12-Α-Dihydroxycholanic Acid

CAS: 911-40-0

7-Keto-3Α,12-Α-Dihydroxycholanic Acid

Purezza: 97%

Peso molecolare: 406.57g/mol

Ref: 54-OR1026113

7-keto-deoxycholic acid

CAS: 911-40-0

7-keto-deoxycholic acid is converted from Lactobacillus and Bifidobacterium with specific condition and from cholic acid in vitro.

Formula: C₂₄H₃₈O₅

Purezza: 99.63% - 99.63%

Colore e forma: Solid

Peso molecolare: 406.56

Ref: TM-TN7120

7-keto-deoxycholic acid

CAS: 911-40-0

7-keto-deoxycholic acid

Purezza: ≥98%

Peso molecolare: 406.56g/mol

Ref: 54-BUP15614

7-oxo-Deoxycholic acid

CAS: 911-40-0

Formula: C24H38O5

Purezza: >96%

Colore e forma: Solid

Peso molecolare: 406.56

Ref: 48-65-1117

7-Keto-3α,12-α-dihydroxycholanic Acid

Prodotto controllato

CAS: 911-40-0

Formula: C₂₄H₃₈O₅

Colore e forma: Off White Solid

Peso molecolare: 406.56

Ref: TR-K188480

7-Keto-3α,12-α-dihydroxycholanic acid

Prodotto controllato

CAS: 911-40-0

7-Keto-3α,12-α-dihydroxycholanic acid is a lipid molecule that belongs to the class of sodium salts. It has been shown to form stable complexes with biological samples and is useful for sample preparation before analysis. 7-Keto-3α,12-α-dihydroxycholanic acid has been used in studies of hepatic steatosis in rats, which demonstrated statistically significant changes in liver fat content. This molecule also may be involved in bowel disease because it is a precursor for bile acids and the synthesis of cholesterol. 7KDHC has been associated with redox potential and microbial metabolism. 7KDHC may also have anti-inflammatory effects that help reduce symptoms of inflammatory bowel disease (IBD).

Formula: C₂₄H₃₈O₅

Purezza: Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 406.56 g/mol

Ref: 3D-FK24796

7-Ketodeoxycholic acid

CAS: 911-40-0

Formula: C₂₄H₃₈O₅

Peso molecolare: 406.56

Ref: ST-EA-CP-U1016

7-Ketodeoxycholic Acid

CAS: 911-40-0

Formula: C₂₄H₃₈O₅

Peso molecolare: 406.56

Ref: ST-EA-CP-C93031