CAS 926259-99-6

N-(2-Aminophenyl)pyrazine-2-carboxamide

CAS: 926259-99-6

Formula: C₁₁H₁₀N₄O

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 214.2233

Ref: IN-DA00GU83

BG45

CAS: 926259-99-6

BG45

Purezza: ≥98%

Peso molecolare: 214.22g/mol

Ref: 54-BUP10450

BG45

CAS: 926259-99-6

BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.

Formula: C₁₁H₁₀N₄O

Purezza: 99.77%

Colore e forma: Solid

Peso molecolare: 214.22

Ref: TM-T2294

N-(2-Aminophenyl)pyrazine-2-carboxamide

CAS: 926259-99-6

Purezza: 99%

Peso molecolare: 214.2279968

Ref: 10-F863782

BG45

Prodotto controllato

CAS: 926259-99-6

Applications BG45 acts as an HDAC class I inhibitor with selectvity for HDAC3. HDACs represent novel targets for anti-tumer drugs treating various cancers including multiple myeloma cancer.
References Minami, J. et al.: Leukemia, 28, 680 (2014); Pinder, J. et al.: Pinder, J. et al.: Tetrahedron. Lett., 55, 4853 (2014);

Formula: C₁₁H₁₀N₄O

Colore e forma: Neat

Peso molecolare: 214.22

Ref: TR-B366500

BG45

CAS: 926259-99-6

BG45 is a mutant strain of the bacterium Lactobacillus plantarum that has been modified to express a protein that inhibits the growth of tumor cells. The BG45 bacterium is capable of inducing an inhibitory effect on cancer cell growth in vitro and in vivo. This inhibitory effect is due to the immunomodulatory effects of the bacterium, which are mediated by suppressing genes that are involved in immune response and lipid metabolism. Furthermore, BG45 has significant cytotoxicity when cultured with human cancer cells and suppressed tumor growth in murine xenografts. This bacterium also has lysine residues that can be used as an indicator for identifying nutrient-poor environments such as microenvironments, suggesting that it may have potential use as a probiotic for patients with gastrointestinal disorders. In vitro assays have shown that BG45 produces fatty acids, which may be responsible for its activity against tumors.

Formula: C₁₁H₁₀N₄O

Purezza: Min. 95%

Peso molecolare: 214.22 g/mol

Ref: 3D-BMB25999